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Chloramphenicol
go.drugbank.com/drugs/DB00446ApprovedInvestigationalVet approvedWithdrawnAn antibiotic first isolated from cultures of _Streptomyces venezuelae_ in 1947 but now produced synthetically. … (From Martindale, The Extra Pharmacopoeia, 29th ed, p106) The FDA has withdrawn all oral drug products containing chloramphenicol, due to the high risk of fatal aplastic anemia associated with this
Mixtures: CORTIFENOL H POMADA OFTALMICA 4 G, ยาฉีดมาโนซีติน 250 มก.Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP2C19 InhibitorsEstramustine
go.drugbank.com/drugs/DB01196ApprovedWithdrawnA nitrogen mustard linked to estradiol, usually as phosphate; used to treat prostatic neoplasms; also has radiation protective properties.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: ESTRACYT 140 MG KAPSUL, 100 ADET, ESTRACYT CAPSULE 140 mgLinezolid
go.drugbank.com/drugs/DB00601ApprovedInvestigationalLinezolid is a synthetic antibiotic which is used for the treatment of infections caused by aerobic Gram-positive bacteria. … [A233425] A second member of this class, [tedizolid], was approved by the FDA in 2014 and is considered generally more effective and tolerable than its predecessor.
Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substratesProducts: LINEZOLID AL 600 MG FTA, ZIZOLID 100 MG / 5 ML ORAL SÜSPANSİYON HAZIRLAMAK İÇİN KURU TOZ, 150 MLDipyridamole
go.drugbank.com/drugs/DB00975ApprovedInvestigationalA phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin.
Mixtures: Aspirin and Extended - Release Dipyridamole Capsules, 25 mg / 200 mg, Aspirin and Extended - Release Dipyridamole Capsules, 25 mg / 200 mgInternational brands: Cleridium 150Glyburide
go.drugbank.com/drugs/DB01016ApprovedInvestigationalGlyburide is a second generation sulfonylurea used to treat patients with diabetes mellitus type II. … [L8117] A formulation with metformin was granted FDA approval on on 31 July 2000.[L8120]
Mixtures: DUO-ANGLUCID, DUPLAX 250 MG/1.25 MG FILM KAPLI TABLET, 120 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 InhibitorsIopromide
go.drugbank.com/drugs/DB09156ApprovedIt functions as a contrast agent by opacifying blood vessels in the flow path of the contrast agent, permitting radiographic visualization of the internal structures until significant hemodilution occurs … Iopromide is a low osmolar, non-ionic X-ray contrast agent for intravascular administration.
Categories: Compounds used in a research, industrial, or household settingProducts: RAVİSTU 300 MG I/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 100 ML, İOPOLİMİD 370 MG I/ML ENJEKSİYONLUK ÇÖZELTİ, 100 MLBendamustine
go.drugbank.com/drugs/DB06769ApprovedInvestigationalThrough this function as an alkylating agent, bendamustine causes intra- and inter-strand crosslinks between DNA bases resulting in cell death. … Bendamustine is a bifunctional mechlorethamine derivative capable of forming electrophilic alkyl groups that covalently bond to other molecules.
Categories: Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index, P-glycoprotein substrates with a Narrow Therapeutic IndexProducts: BENDAMUSTINA DR. REDDY'S, GENSTINA® POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLEPemetrexed
go.drugbank.com/drugs/DB00642ApprovedInvestigationalPemetrexed is a chemotherapy drug that is manufactured and marketed by Eli Lilly and Company under the brand name Alimta.
Categories: Cytochrome P-450 Substrates, OAT3/SLC22A8 Substrates with a Narrow Therapeutic IndexProducts: PEMETREXED 500 MG POLVO LIOFILIZADO PARA SOLUCIÓN DE INFUSIÓN., PEMETREXED DR. REDDY'SNuvaxovid
go.drugbank.com/drugs/DB15810ApprovedInvestigationalNuvaxovid (NVX-CoV2373) contains a recombinant mutant S protein that is codon-optimized for baculovirus-mediated expression in Sf9 cells derived from _Spodoptera frugiperda_ together with a Matrix-M adjuvant … [L42450,L42965] An updated formulation covering the Omicron XBB.1.5 subvariant was approved in October 2023 in the EU[L48897] and in December 2023 in Canada.
Synonyms: SARS-CoV-2 rS, SARS-CoV-2 rS Nanoparticle VaccineBenzydamine
go.drugbank.com/drugs/DB09084ApprovedInvestigationalBenzydamine (also known as Tantum Verde or Difflam), available as the hydrochloride salt, is a locally-acting nonsteroidal anti-inflammatory drug (NSAID) with local anaesthetic and analgesic properties … aspirin-like NSAIDs but facilitate benzydamine's mechanism of action as an effective locally-acting NSAID with local anaesthetic and analgesic properties.
Mixtures: TANTUM VERDE DUO 22,5 MG+18 MG/15 ML GARGARA, TANTUM VERDE DUO FORTE 45 MG+18 MG/15 ML GARGARAProducts: Nu-benzydamine Oral Rinse, BENZIRIN® ROSA DUCHA LISTA PARA SU USO