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Diodone
go.drugbank.com/drugs/DB13568ExperimentalCategories: Diagnostic Uses of Chemicals, Compounds used in a research, industrial, or household settingThyroglobulin
go.drugbank.com/drugs/DB01584ApprovedWithdrawnThe active form of thyroxine, triiodothyronine, is produced both within the thyroid gland and periphery by 5'-deiodinase. … Patients with Hashimoto's thyroiditis or Graves' disease, frequently develop antibodies against thyroglobulin. Thyroglobulin is used to treat hypothyroidism.
Hyaluronidase
go.drugbank.com/drugs/DB14740ApprovedInvestigational[L13338] The action of hyaluronidase was first described in 1936, and named in 1939. … [A199047] Hyaluronidase was first used in prescription products in the United States on 5 May 2004.[L13338]
Sotalol
go.drugbank.com/drugs/DB00489ApprovedInvestigationalin atrial fibrillation or flutter. … [A178579] It was the first of the class III anti arrhythmic drugs.[A178579] Sotalol was first approved as an oral tablet on 30 October 1992.
Products: SOTALEX 160 MG, PMS-sotalol - 80 mgSerdexmethylphenidate
go.drugbank.com/drugs/DB16629Approved[A230698, A230703] The underlying cause of ADHD is unclear but likely involves dysfunction in dopaminergic and noradrenergic neurotransmission, as evidenced by the clear beneficial effect of CNS stimulants … [L32298, L32323] Serdexmethylphenidate was granted FDA approval on March 2, 2021, and is currently marketed as a combination capsule with [dexmethylphenidate] under the trademark AZSTARYS™ by KemPharm
Ioflupane I-123
go.drugbank.com/drugs/DB08824ApprovedInvestigationalIoflupane (I-123) is a radiopharmaceutical used to image dopamine neurons and diagnose Parkinsonian syndromes.
Categories: Diagnostic Uses of ChemicalsTemocillin
go.drugbank.com/drugs/DB12343ApprovedInvestigationalWithdrawnTemocillin has been investigated in Infection, Liver Dysfunction, and Urinary Tract Infection.
Categories: combinations of penicillinsEquine Botulinum Neurotoxin F Immune FAB2
go.drugbank.com/drugs/DB13901ApprovedEquine Botulinum Neurotoxin F Immune FAB2 is composed of a mixture of immune globulin fragments purified from plasma of horses that were previously immunized with botulinum toxin serotype F. … It is intravenously administered for the treatment of symptomatic botulism following documented or suspected exposure to botulinum neurotoxin serotypes F in adults and pediatric patients.
Valbenazine
go.drugbank.com/drugs/DB11915ApprovedInvestigational[A261125] On August 2023, valbenazine was again approved by the FDA for the treatment of chorea associated with Huntington's disease respectively. … The reduction in chorea severity was observed as early as 2 weeks after starting treatment with an initial dose of 40 mg.[L47910]
Products: REMLEAS HARD CAPSULES 40 MGOxycodegol
go.drugbank.com/drugs/DB14146InvestigationalNektar Therapeutics has filed an application for FDA approval of Loxicodegol for use in the treatment of chronic lower back pain [L3263] … The lack of abuse potential is believed to be due to the drug's slow rate of entry into brain, a unique characteristic compared to others in the opioid class [A33997, A34016].
Categories: Heterocyclic Compounds with 4 or More Rings