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Hydroxyethyl cellulose
go.drugbank.com/drugs/DB11602ApprovedIt is used as a key ingredient in many household cleaning products, lubricants and cosmetics due to its non-ionic and water-soluble nature. … Hydroxyethyl cellulose is a polysaccharide derivative with gel thickening, emulsifying, bubble-forming, water-retaining and stabilizing properties.
Salts: Hydroxyethyl cellulose (140 MPa.s at 5%), Hydroxyethyl cellulose (280 MPa.s at 5%)Categories: Compounds used in a research, industrial, or household settingSelinexor
go.drugbank.com/drugs/DB11942ApprovedInvestigational[L7123] Selinexor was also granted accelerated approval for the treatment of adult patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL) that have gone through at least 2 lines of … Selinexor is a first-in-class selective inhibitor of nuclear transport (SINE) compound.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: Nexpovio 20 mg Film Kaplı Tablet, 8 TABLET, Nexpovio 20 mg Film Kaplı Tablet, 20 TABLETIndapamide
go.drugbank.com/drugs/DB00808ApprovedInvestigational[A204155] Characterized by an office blood pressure of ≥140/90, hypertension is pervasive and impacts an estimated 25% of adults globally. … [A204155] Treatment for hypertension should include a number of lifestyle changes (ie. reduced sodium intake) along with pharmacotherapy - it should be noted that treatment with several antihypertensive
Mixtures: Triplixam 10 mg/2,5 mg/5 mg Filmtabletten, Triplixam 5 mg/1,25 mg/10 mg FilmtablettenCategories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 SubstratesVildagliptin
go.drugbank.com/drugs/DB04876ApprovedInvestigationalIt is used to manage type II diabetes mellitus, where GLP-1 secretion and insulinotropic effects are impaired. … [A232488] By inhibiting DPP-4, vildagliptin prevents the degradation of glucagon-like peptide 1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), which are incretin hormones that promote
Mixtures: VILMET 50 MG/1000 MG FILM KAPLI TABLET ,1TABLET, 20 ADET, GALVUS MET 50/850 MG FILM KAPLI TABLET, 120 ADETCategories: Glucagon-Like Peptide 1, Heterocyclic Compounds, 1-RingColistin
go.drugbank.com/drugs/DB00803ApprovedInvestigationalIt is composed of Polymyxins E1 and E2 (or Colistins A, B, and C) which act as detergents on cell membranes. … Colistin is less toxic than Polymyxin B, but otherwise similar; the methanesulfonate is used orally.
Mixtures: Coly-Mycin S, Coly-Mycin SCategories: Drugs that are Mainly Renally Excreted with a Narrow Therapeutic IndexTD-0903
go.drugbank.com/drugs/DB16463InvestigationalTD-0903 was investigated in clinical trials for its potential to treat acute lung injury (ALI) associated with COVID-19, including NCT04350736, NCT05091723 (a pharmacokinetics study in healthy participants … with supplemental oxygenation), and NCT04402866 (focused on ALI and lung inflammation associated with COVID-19)
Categories: Heterocyclic Compounds, 2-Ring, Heterocyclic Compounds, 1-RingSynonyms: (3-(DIMETHYLAMINO)AZETIDIN-1-YL)((6S)-2-(6-(2-ETHYL-4-HYDROXYPHENYL)-1H-INDAZOL-3-YL)-5-(PROPAN-2-YL)-4,5,6,7-TETRAHYDRO-1H-IMIDAZO(4,5-C)PYRIDIN-6-YL)METHANONE, METHANONE, (3-(DIMETHYLAMINO)-1-AZETIDINYL)((6S)-2-(6-(2-ETHYL-4-HYDROXYPHENYL)-1H-INDAZOL-3-YL)-4,5,6,7-TETRAHYDRO-5-(1-METHYLETHYL)-3H-IMIDAZO(4,5-C)PYRIDIN-6-YL)-Londamocitinib
go.drugbank.com/drugs/DB19190InvestigationalLondamocitinib is under investigation in clinical trial NCT06020014 (Phase 2a Study to Assess the Efficacy and Safety of AZD4604 in Adult Patients With Moderate-to-severe Asthma Uncontrolled on Medium-high
Synonyms: (R)-N-(3-(5-Fluoro-2-((2-fluoro-3-(methylsulfonyl)phenyl)amino)pyrimidin-4-yl)-1H-indol-7-yl)-3-methoxy-2-(4-methylpiperazin-1-yl)propanamide, 1-piperazineacetamide, n-(3-(5-fluoro-2-((2-fluoro-3-(methylsulfonyl)phenyl)amino)-4-pyrimidinyl)-1h-indol-7-yl)-.alpha.-(methoxymethyl)-4-methyl-, (.alpha.r)-Fallypride F-18
go.drugbank.com/drugs/DB19254InvestigationalFallypride F-18 is under investigation in clinical trial NCT00846040 (Reduced Carbohydrate Versus Fat in Obese Subjects).
Synonyms: Benzamide, 5-(3-(fluoro-18f)propyl)-2,3-dimethoxy-n-(((2s)-1-(2-propen-1-yl)-2-pyrrolidinyl)methyl)-, F-18 fallyprideUstekinumab
go.drugbank.com/drugs/DB05679ApprovedInvestigationalUstekinumab is a human immunoglobulin (Ig) G1 kappa monoclonal antibody directed against interleukin(IL)-12 and IL-23, which are cytokines that are involved in immune and inflammatory responses. … [A187349] It was generated via recombinant human IL-12 immunization of human Ig (hu-Ig) transgenic mice.
Categories: Interleukin-12 Antagonist, Interleukin-23 AntagonistProducts: STELARA® 90 MG/ML, Stelara Solution for Injection in Pre-Filled Syringe 90 mg/1 mLFerrous fumarate
go.drugbank.com/drugs/DB14491ApprovedInvestigationalUsed in treatment of iron deficiency anemia.
Mixtures: Vitamin C 202,8 mg/0,8 mg/100 mg - Hartkapseln, FERROZINC KAPSUL, 20 ADETSynonyms: Iron(2+) fumarate