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Topiramate
go.drugbank.com/drugs/DB00273ApprovedInvestigational[L10550] Characteristics that distinguish topiramate from other antiepileptic drugs are a monosaccharide chemical structure containing a sulfamate, and 40% of its mass accounted for by oxygen. … Topiramate is a anti-epileptic drug used to manage seizures and prevent migraines.[A175249] It was initially approved by the FDA in 1996.
Mixtures: Phentermine and topiramate, Phentermine and topiramateCategories: Alimentary Tract and Metabolism, phentermine and topiramateEsomeprazole
go.drugbank.com/drugs/DB00736ApprovedInvestigationalEsomeprazole is the s-isomer of [DB00338], which is a racemate of the S- and R-enantiomer. … [A177571] Rapid discontinuation of PPIs such as esomeprazole may cause a rebound effect and a short term increase in hypersecretion.
Mixtures: OCAM PROTECT 15 MG, OCAM PROTECT ® 15 MG TABLETAS DE LIBERACION RETARDADACategories: Heterocyclic Compounds, 1-Ring, Alimentary Tract and MetabolismCiclopirox
go.drugbank.com/drugs/DB01188ApprovedInvestigationalCiclopirox olamine (used in preparations called Batrafen, Loprox, Mycoster, Penlac and Stieprox) is a synthetic antifungal agent for topical dermatologic treatment of superficial mycoses.
Mixtures: Ciclopirox 3% / Itraconazole 5% / Urea 20%, Ciclopirox 8% / Fluconazole 1% / Terbinafine HCl 1%Categories: Heterocyclic Compounds, 1-Ring, Vaginal Creams, Foams, and JelliesSirolimus
go.drugbank.com/drugs/DB00877ApprovedInvestigational[A1320] Sirolimus was first approved by the FDA in 1999 for the prophylaxis of organ rejection in patients aged 13 years and older receiving renal transplants. … [L39267] Sirolimus was also investigated in other cancers such as skin cancer, Kaposi’s Sarcoma, cutaneous T-cell lymphomas, and tuberous sclerosis.
Categories: Sirolimus and Prodrugs, Antineoplastic and Immunomodulating AgentsProducts: RAPAMUNE 1 MG FILM DRAJE, 30 ADET, RAPAMUNE TABLET 1 mgOrnithine
go.drugbank.com/drugs/DB00129ApprovedInvestigationalNutraceuticalL-Ornithine allows for the disposal of excess nitrogen and acts as a precursor of citrulline and arginine.
Mixtures: AMINOPLASMAL-5% E INFUSION, NUMETA PED G 19 % E INFÜZYON IÇIN EMÜLSIYON, 1000 MLCategories: Bile and Liver Therapy, Alimentary Tract and MetabolismAlfacalcidol
go.drugbank.com/drugs/DB01436ApprovedInvestigationalNutraceuticalAlfacalcidol, or 1-alpha-hydroxycholecalciferol or 1-alpha-hydroxyvitamin D3, is a non-endogenous analogue of [vitamin D]. … vitamin D resistant rickets and osteomalacia.
Categories: Vitamin D and Analogues, Alimentary Tract and MetabolismSynonyms: (5Z,7E)-9,10-seco-5,7,10(19)-cholestatrien-1α,3β-diol, 1-hydroxycholecalciferolTocilizumab
go.drugbank.com/drugs/DB06273ApprovedInvestigationalTocilizumab is a recombinant humanized monoclonal antibody IL-6 receptor inhibitor used to treat inflammatory and autoimmune conditions. … [A193281] Tocilizumab was granted FDA approval on 8 January 2010 to treat a number of inflammatory and autoimmune disorders, such as different types of arthritis and cytokine release syndrome.
Categories: Experimental Unapproved Treatments for COVID-19, Amino Acids, Peptides, and ProteinsProducts: ACTEMRA 200 MG/10 ML IV INFUZYONLUK COZELTI KONSANTRESI İÇEREN FLAKON, 1 ADET, ACTEMRA 200 MG/10 ML IV INFUZYONLUK COZELTI KONSANTRESI İÇEREN FLAKON, 4 ADETMetformin
go.drugbank.com/drugs/DB00331ApprovedInvestigationalIt is commonly described as an "insulin sensitizer", leading to a decrease in insulin resistance and a clinically significant reduction of plasma fasting insulin levels. … Metformin is a biguanide antihyperglycemic agent and first-line pharmacotherapy used in the management of type II diabetes.
Mixtures: DAPAKEM-M 10/1000, XIGDUO XR (TABLETS 10 MG/1000 MG)Categories: MATE 1 Substrates, MATE 2 SubstratesTamoxifen
go.drugbank.com/drugs/DB00675ApprovedInvestigational[A1026] Tamoxifen was granted FDA approval on 30 December 1977.[L7799] … Tamoxifen is a non-steroidal antiestrogen used to treat estrogen receptor positive breast cancers as well as prevent the incidence of breast cancer in high risk populations.
Categories: Antineoplastic and Immunomodulating Agents, Hormone Antagonists and Related AgentsSynonyms: 1-p-beta-Dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene, 1-para-beta-Dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-eneDorzolamide
go.drugbank.com/drugs/DB00869ApprovedInvestigationalDorzolamide is a non-bacteriostatic sulfonamide derivative [A1304] and topical carbonic anhydrase (CA) inhibitor that treats elevated intraocular pressure (IOP) associated with open-angle glaucoma and … [L11377] It works by blocking an enzyme in the ciliary process that regulates ion balance and fluid pressure in the eyes.
Mixtures: Dorzolamid + Timolol 1A Pharma 20 mg/ml + 5 mg/ml - Augentropfen, Lösung, Cosopt 20 mg/ml + 5 mg/ml AugentropfenCategories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 Substrates