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Lofexidine
go.drugbank.com/drugs/DB04948ApprovedInvestigationalLofexidine is a non-opioid centrally acting alpha2-adrenergic receptor agonist that was first approved for the treatment of opioid withdrawal in the United Kingdom in 1992.
Synonyms: 2-(alpha-(2,6-Dichlorophenoxy)ethyl)2-imidazolineCategories: Adrenergic alpha-2 Receptor Agonists, Central alpha-2 Adrenergic Agonist(5Z)-5-[(5-ethylfuran-2-yl)methylidene]-2-[[(S)-(4-fluorophenyl)-(2H-tetrazol-5-yl)methyl]amino]-1,3-thiazol-4-one
go.drugbank.com/drugs/DB08710ExperimentalSynonyms: (5Z)-5-[(5-ethylfuran-2-yl)methylidene]-2-[[(S)-(4-fluorophenyl)-(2H-tetrazol-5-yl)methyl]amino]-1,3-thiazol-4-oneAmylocaine
go.drugbank.com/drugs/DB09088ApprovedWithdrawnDespite the introduction of using cocaine injections for regional anesthesia in 1884, non-addictive substitutes were sought after immediately . Finally, in 1903 the world's first synthetic and non-addictive local anesthetic, amylocaine, ...
Synonyms: 1-(Dimethylamino)-2-methyl-2-butanol benzoate1-[Glycerolylphosphonyl]-2-[8-(2-Hexyl-Cyclopropyl)-Octanal-1-Yl]-3-[Hexadecanal-1-Yl]-Glycerol
go.drugbank.com/drugs/DB03979ExperimentalSynonyms: 1-[Glycerolylphosphonyl]-2-[8-(2-Hexyl-Cyclopropyl)-Octanal-1-Yl]-3-[Hexadecanal-1-Yl]-Glycerol2',3'-O-{4-[Hydroxy(oxido)-λ5-azanylidene]-2,6-dinitro-2,5-cyclohexadiene-1,1-diyl}adenosine 5'-(tetrahydrogen triphosphate)
go.drugbank.com/drugs/DB02524ExperimentalSynonyms: 2',3'-O-{4-[Hydroxy(oxido)-λ5-azanylidene]-2,6-dinitro-2,5-cyclohexadiene-1,1-diyl}adenosine 5'-(tetrahydrogen triphosphate)FK352B
go.drugbank.com/drugs/DB06484ExperimentalFK352B is a adenosine A1 antagonist that is developed for the treatment of dialysis-induced hypotension.
Synonyms: 2-((2R)-1-((2E)-3-(2-PHENYLPYRAZOLO(1,5-A)PYRIDIN-3-YL)PROP-2-ENOYL)PIPERIDIN-2-YL)ACETIC ACID, 2-PIPERIDINEACETIC ACID, 1-((2E)-1-OXO-3-(2-PHENYLPYRAZOLO(1,5-A)PYRIDIN-3-YL)-2-PROPEN-1-YL)-, (2R)-Categories: Heterocyclic Compounds, 1-RingRecilisib
go.drugbank.com/drugs/DB18310ExperimentalSynonyms: 4-((1e)-2-(((4-chlorophenyl)methyl)sulfonyl)ethenyl)benzoic acid, Benzoic acid, 4-((1e)-2-(((4-chlorophenyl)methyl)sulfonyl)ethenyl)-Evenamide
go.drugbank.com/drugs/DB18775InvestigationalSynonyms: 2-((2-(3-butoxyphenyl)ethyl)amino)-n,n-dimethylacetamide, Acetamide, 2-((2-(3-butoxyphenyl)ethyl)amino)-n,n-dimethyl-VMD-928
go.drugbank.com/drugs/DB18052InvestigationalSynonyms: 4-((4-AMINO-3-(4-CYCLOHEXYLPIPERAZIN-1-YL)-9,10-DIOXO-9,10-DIHYDROANTHRACEN-1-YL)AMINO)BENZOIC ACID, 4-{[4-Amino-3-(4-cyclohexylpiperazin-1-yl)-9,10-dioxo-9,10-dihydroanthracen-1-yl]amino}benzoic acidKOS-2187
go.drugbank.com/drugs/DB05946ExperimentalKOS-2187, a novel erythromycin-based motilin agonist, or motilide, as a clinical candidate for the treatment of gastrointestinal motility disorders such as gastroparesis and gastroesophageal reflux disease
Synonyms: (3R,4S,5S,6R,7R,9R,10S,11S,12R,13S,14R)-7,10,12,13-tetrahydroxy-4-(5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl)oxy-6-[3-hydroxy-6-methyl-4-[methyl(propan-2-yl)amino]oxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl, -14-phenyl-oxacyclotetradecan-2-one