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Dipyrithione
go.drugbank.com/drugs/DB11327Approved[A32829] Interestingly, dipyrithione has been studied and shown to have cytotoxic and potent broad-spectrum antitumor activity, which suggests a potential basis for an anticancer drug development. … [L2615] Dandruff is a common scalp disease affecting >40% of the world's adult population, and may be caused by fungi such as _Malassezia globosa_ and _M. restricta_.[A32162]
Categories: Heterocyclic Compounds, 1-RingPimethixene
go.drugbank.com/drugs/DB13292ApprovedIt is an anticholinergic used in the treatment of bronchitis.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 3-RingEtilefrine
go.drugbank.com/drugs/DB08985ApprovedWithdrawnEtilefrine is an adrenergic agonist that appears to interact with beta-1 and some alpha-adrenergic receptors. It has been used as a vasoconstrictor agent.
Categories: Adrenergic beta-1 Receptor Agonists, Compounds used in a research, industrial, or household settingProducts: EFFORTIL® AMPOLLAS, EFFORTIL LOESUNG Z TROPFENCanrenoic acid
go.drugbank.com/drugs/DB09015ApprovedInvestigationalWithdrawnCanrenoic acid (as the salt potassium canrenoate) is an aldosterone antagonist. Like spironolactone, it is a prodrug, which is metabolized to canrenone in the body.
Dexmedetomidine
go.drugbank.com/drugs/DB00633ApprovedInvestigationalVet approvedAn agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of dexmedetomidine.
Synonyms: (+)-4-((S)-α,2,3-trimethylbenzyl)imidazole, (+)-4-((S)-alpha,2,3-Trimethylbenzyl)imidazoleCategories: Cytochrome P-450 Substrates, Adrenergic alpha-2 Receptor AgonistsPhenserine
go.drugbank.com/drugs/DB04892InvestigationalIf this is substantiated in an ongoing clinical trial then phenserine may open the door to an entirely new type of treatment for AD. … Unlike currently marketed AChE inhibitors, it has a dual mechanism of action that also includes anti-amyloid activity, which may confer disease-modifying effects in patients with AD.
Categories: Heterocyclic Compounds, 2-RingLubiprostone
go.drugbank.com/drugs/DB01046ApprovedInvestigationalA prostaglandin E1 derivative, lubiprostone is a bicyclic fatty acid that activates ClC-2 chloride channels located on the apical side of the gastrointestinal epithelial cells. … Lubiprostone is a medication used in the management of idiopathic chronic constipation.
Categories: Prostaglandins EProducts: MOVIPROST ® 8 MCG, อามิทีซา 8 ไมโครกรัมAfimetoran
go.drugbank.com/drugs/DB16580InvestigationalAfimetoran is an immunomodulator and an antagonist of toll-like receptors 7 and 8.
Insulin aspart
go.drugbank.com/drugs/DB01306ApprovedInvestigationalblood sugar levels can climb to dangerously high levels and can result in symptoms such as fatigue, headache, blurred vision, and increased thirst. … Insulin is an important treatment in the management of Type 1 Diabetes (T1D) which is caused by an autoimmune reaction that destroys the beta cells of the pancreas, resulting in the body not being able
Mixtures: Ryzodeg® FlexTouch® 100 U/ml Solution for Injection, RYZODEG PENFİLL 100 U/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KARTUŞ, 5 ADETCategories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 Enzyme InducersInsulin detemir
go.drugbank.com/drugs/DB01307ApprovedInvestigational[A2358, A2359, A2360, A44] Without an adequate supply of insulin to promote absorption of glucose from the bloodstream, blood sugar levels can climb to dangerously high levels and can result in symptoms … [A2358, A2359, A2360, A44] Insulin is an important treatment in the management of Type 1 Diabetes (T1D) which is caused by an autoimmune reaction that destroys the beta cells of the pancreas, resulting
Categories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 Enzyme InducersProducts: Levemir® FlexPen® 100 U/ml Solution for Injection in Pre-filled Pen, 100 U/ML