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Calfactant
go.drugbank.com/drugs/DB06415ApprovedInvestigationalIt adsorbs to the air:fluid interface in the lungs and works to reduce surface tension, in a manner similar to endogenous pulmonary surfactant. … Calfactant is approved for use in the United States of America. It is used to prevent or treat respiratory distress syndrome in premature infants with lung surfactant deficiency.
Synonyms: SF-RI 1Products: INFASURF 35 MG/ML INTRATRAKEAL SÜSPANSIYON,3 ML, INFASURF 35 MG/ML INTRATRAKEAL SÜSPANSIYON ,6 MLMonobenzone
go.drugbank.com/drugs/DB00600ApprovedWithdrawnMonobenzone is the monobenzyl ether of hydroquinone used medically for depigmentation. … It exerts a depigmenting effect on skin of mammals by increasing the excretion of melanin from the melanocytes. It may also cause destruction of melanocytes and permanent depigmentation.
Synonyms: 4-(Benzyloxy)phenol, 4-BenzyloxyphenolCalcium gluconate
go.drugbank.com/drugs/DB11126ApprovedInvestigationalVet approvedEach 10 mL of the injection provides 93 mg elemental calcium (Ca++) equivalent to 1 g of calcium gluconate. … Calcium gluconate is used as mineral supplement and medication when there is insufficient calcium in the diet.
Mixtures: ELETTROLITICA DI REINTEGRAZIONE CON GLUCOSIO E SODIO GLUCONATO FKI, ELETTROLITICA DI REINTEGRAZIONE CON GLUCOSIO E SODIO GLUCONATO FKISynonyms: D-gluconic acid, calcium salt (2:1)Erdafitinib
go.drugbank.com/drugs/DB12147ApprovedInvestigational[L5956, L5959] At the same time, the FDA also approved the therascreen FGFR RGQ RT-PCR Kit (Qiagen) for utilization as a companion diagnostic with erdafitinib for selecting patients for the indicated therapy … tool kit to treat such a prevalent medical condition.
Categories: Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic Index, P-glycoprotein substrates with a Narrow Therapeutic IndexProducts: BALVERSA 3 MG FİLM KAPLI TABLET, 56 ADET, BALVERSA 3 MG FİLM KAPLI TABLET, 84 ADETN-acetyltyrosine
go.drugbank.com/drugs/DB11102ApprovedInvestigationalN-acetyltyrosine is administered as parenteral nutrition or intravenous infusion due to its enhanced solubility compared to tyrosine [A32652]. … N-acetyltyrosine, also referred to as N-acetyl-L-tyrosine, is used in place of as a tyrosine precursor. [DB00135] is a non-essential amino acid with a polar side group.
Mixtures: AMINOPLASMAL-5% E INFUSION, AMINOPLASMAL-10% E INFUSIONSynonyms: (+)-(2s)-2-(acetylamino)-3-(4-hydroxyphenyl)propanoic acid, (2s)-2-acetylamino-3-(4-hydroxyphenyl)propanoic acidCinnamaldehyde
go.drugbank.com/drugs/DB14184ApprovedIt occurs naturally in the bark of cinnamon trees and other species of the genus Cinnamomum such as camphor and cassia. Sensitivity to cinnamaldehyde may be identified with a clinical patch test. … Cinnamaldehyde is a naturally occurring flavonoid that gives the spice cinnamon its flavour and odour.
Categories: Compounds used in a research, industrial, or household settingSynonyms: (E)-3-Phenyl-2-propenal, (E)-3-PhenylpropenalPralatrexate
go.drugbank.com/drugs/DB06813ApprovedInvestigational[A246703] As such, pralatrexate is thought to have a better therapeutic window compared to other antifolate analogs due to the novel target of RFC. … Pralatrexate is an antifolate for the treatment of relapsed or refractory peripheral T-cell lymphoma [L37674].
Categories: Heterocyclic Compounds, 2-RingSynonyms: (2S)-2-({4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoyl}amino)pentanedioic acid, (2S)-2-((4-((1RS)-1-((2,4-Diaminopteridin-6-yl)methyl)but-3-ynyl)benzoyl)amino)pentanedioic acidBexagliflozin
go.drugbank.com/drugs/DB12236ApprovedInvestigational[A256413] SGLT2 is responsible for 60% to 90% of renal glucose re-uptake, and unlike other isoforms such as SGLT1, SGLT2 is mainly expressed in the kidney. … [A256423,L44758] In January 2023, bexagliflozin was approved by the FDA for the treatment of adults with type 2 diabetes.
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesSynonyms: D-glucitol, 1,5-anhydro-1-C-(4-chloro-3-((4-(2-(cyclopropyloxy)ethoxy)phenyl)methyl)phenyl)-, (1s)-, (2S,3R,4R,5S,6R)-2-(4-chloro-3-((4-(2-(cyclopropyloxy)ethoxy)phenyl)methyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triolDenileukin diftitox
go.drugbank.com/drugs/DB00004ApprovedInvestigationalapproved to treat a human disease in the US. … [L51254] It is designed to deliver diphtheria toxin into IL-2 receptor-expressing cancer cells to cause cell death.
Synonyms: N-L-METHIONYL-387-L-HISTIDINE-388-L-ALANINE-1-388-TOXIN (CORYNEBACTERIUM DIPHTHERIAE STRAIN C7) (388->2') PROTEIN WITH 2-133-INTERLEUKIN 2 (HUMAN CLONE PTIL2-21A), N-MET-187-HIS-388-ALA-1-388-TOXIN (CORYNEBACTERIUM DIPHTHERIAE C7) WITH 1-133-INTERLEUKIN 2Sertraline
go.drugbank.com/drugs/DB01104ApprovedInvestigationalSertraline is a popular antidepressant medication commonly known as a selective serotonin reuptake inhibitor (SSRI), and is similar to drugs such as [Citalopram] and [Fluoxetine]. … Several weeks of therapy with sertraline may be required before beneficial effects are noticed.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, P-glycoprotein inhibitorsSynonyms: (1S,4S)-sertraline, (1S-cis)-1,2,3,4-tetrahydro-4-(3,4-dichlorophenyl)-N-methyl-1-naphthalenamine