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Displaying results 2771 - 2780 of 10000 in total
  1. Drug

    Bromotheophylline

    go.drugbank.com/drugs/DB14018
    Approved

    [L1082] It is also approved by Health Canada to be used alone or in combination with [DB00316] in OTC products.[L1113] … From this mixture, bromotheophylline acts as a weak diuretic that has been used along with some analgesics to relieve the symptoms of premenstrual syndrome.

    Mixtures: PAMACET 500 MG/25 MG/15 MG FİLM KAPLI TABLET, 40 ADET, PAMACET 500 MG/25 MG/15 MG FİLM KAPLI TABLET, 24 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates
  2. Drug

    Estradiol acetate

    go.drugbank.com/drugs/DB13952
    ApprovedVet approved

    The primary source of estrogen in normally cycling adult women is the ovarian follicle, which secretes 70 to 500 mcg of estradiol daily, depending on the phase of the menstrual cycle. … [DB00783] is commonly produced with an ester side-chain as endogenous estradiol has very low oral bioavailability on its own (2-10%).

    Categories: Cytochrome P-450 CYP1A1 Substrates, Cytochrome P-450 Substrates
  3. Drug

    Voclosporin

    go.drugbank.com/drugs/DB11693
    ApprovedInvestigational

    Within 10 years of being diagnosed with SLE, 5-20% of those suffering from LN develop end-stage kidney disease, a fatal condition. … Early intervention with voclosporin coupled with a kidney response is believed to prevent irreversible damage to the kidney and lead to better long-term clinical outcomes for patients with LN.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inhibitors
  4. Drug

    Dinutuximab

    go.drugbank.com/drugs/DB09077
    ApprovedInvestigational

    By binding to GD2, dinutiximab induces antibody-dependent cell-mediated cytotoxicity and complement-dependent cytotoxicity of tumor cells thereby leading to apoptosis and inhibiting proliferation of the … Current strategies for treatment include immunotherapy with drugs such as dinutuximab to target surviving neuroblastoma cells and to prevent relapse.

  5. Drug

    Florfenicol

    go.drugbank.com/drugs/DB11413
    ExperimentalVet approved

    Florfenicol is a fluorinated synthetic analog of thiamphenicol.

    Products: Florcol Oral Solution 250mg/ml
  6. Indication

    Dementia of the Alzheimer's Type

    go.drugbank.com/conditions/DBCOND0034650
    Drugs: Donepezil
    Synonyms: Dementia due to Alzheimer disease, Dementia due to Alzheimers disease
  7. Indication

    Influenza B Virus Infection

    go.drugbank.com/conditions/DBCOND0042928
    Drugs: Influenza A virus A/Tasmania/503/2020 (H3N2) antigen (MDCK cell derived, propiolactone inactivated) · Influenza B virus B/Brisbane/46/2015 antigen (propiolactone inactivated) · Influenza B virus B/Brisbane/60/2008 recombinant hemagglutinin antigen · Influenza B virus B/Phuket/3073/2013 BVR-1B antigen (propiolactone inactivated)
    Synonyms: Influenza due to unidentified influenza virus with other respiratory manifestations
  8. Drug

    Dostarlimab

    go.drugbank.com/drugs/DB15627
    ApprovedInvestigational

    [L33340] This indication was granted full FDA approval on February 10, 2023.[L45161] Dostarlimab-gxly was granted second accelerated approval for the treatment of solid tumours in the same month. … [L33320] PD-1 receptors are found on T-cells and, when activated, serve to inhibit immune responses - some cancers leverage this system by overexpressing PD-1 ligands, thereby effectively inhibiting the

  9. Drug

    Coco diethanolamide

    go.drugbank.com/drugs/DB18828
    Investigational

    Synonyms: Alkamide 101-cg
  10. Drug

    Naldemedine

    go.drugbank.com/drugs/DB11691
    ApprovedInvestigational

    It is a modified form of [DB00704] to which a side chain has been added to increase molecular weight and polar surface area resulting in restricted transport across the blood brain barrier.