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Displaying results 2781 - 2790 of 10000 in total
  1. Drug

    Farudodstat

    go.drugbank.com/drugs/DB16049
    Investigational

    Farudodstat (ASLAN003) is under investigation in clinical trial NCT03451084 (A Dose Optimisation Study of ASLAN003 in Acute Myeloid Leukemia).

    Synonyms: 2-((3,5-difluoro-3'-methoxy-1,1'-biphenyl-4-yl)amino)nicotinic acid, 2-(3,5-difluoro-3'-methoxybiphenyl-4-ylamino)nicotinic acidCategories: Heterocyclic Compounds, 1-Ring
  2. Drug

    Spermidine

    go.drugbank.com/drugs/DB03566
    Investigational

    Spermidine is a polyamine formed from putrescine. It is found in almost all tissues in association with nucleic acids. … It is found as a cation at all pH values, and is thought to help stabilize some membranes and nucleic acid structures. It is a precursor of spermine.

    Synonyms: N-(3-Aminopropyl)-1,4-butane-diamine, N-(3-aminopropyl)butane-1,4-diamine
  3. Drug

    Narazaciclib

    go.drugbank.com/drugs/DB19038
    Investigational

    Narazaciclib is under investigation in clinical trial NCT06351644 (On 123300 (Narazaciclib) and Dexamethasone in Patients With Relapsed And/or Refractory Multiple Myeloma).

    Synonyms: Pyrido(2,3-d)pyrimidine-6-carbonitrile, 8-cyclopentyl-7,8-dihydro-2-((4-(4-methyl-1-piperazinyl)phenyl)amino)-7-oxo-
  4. Drug

    JS-K

    go.drugbank.com/drugs/DB17257
    Experimental

    Synonyms: 1-piperazinecarboxylic acid, 4-(2-(2,4-dinitrophenoxy)-1-oxidodiazenyl)-, ethyl ester, O2-(2,4-dinitrophenyl) 1-((4-ethoxycarbonyl)piperazin-1-yl)diazen-1-ium-1,2-diolate
  5. Drug

    Domatinostat

    go.drugbank.com/drugs/DB17521
    Investigational

    Synonyms: (e)-n-(2-aminophenyl)-3-(1-((4-(1-methyl-1h-pyrazol-4-yl)phenyl)sulfonyl)-1h-pyrrol-3-yl)acrylamide, 2-propenamide, n-(2-aminophenyl)-3-(1-((4-(1-methyl-1h-pyrazol-4-yl)phenyl)sulfonyl)-1h-pyrrol-3-yl)-, (2e)-
  6. Drug

    Desmeninol

    go.drugbank.com/drugs/DB15832
    Investigational

    Synonyms: 2-Hydroxy-4-(methylthio) butanoic acid, 2-Hydroxy-4-(methylthio)butanoic acid
  7. Drug

    Dazucorilant

    go.drugbank.com/drugs/DB18025
    Investigational

    Synonyms: Methanone, ((4ar)-1-(4-fluorophenyl)-1,4,5,6,7,8-hexahydro-6-((4-(trifluoromethyl)phenyl)sulfonyl)-4ah-pyrazolo(3,4-g)isoquinolin-4a-yl)-2-pyridinyl-Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  8. Drug

    Narsoplimab

    go.drugbank.com/drugs/DB16418
    ApprovedInvestigational

    [A241030, A241040] Mannan-associated lectin-binding serine protease-2 (MASP-2) is a major effector in the complement lectin pathway. … [A241030] Evidence increasingly points to a role for the complement system in TMA.

    Synonyms: IMMUNOGLOBULIN G4-LAMBDA, ANTI-(HOMO SAPIENS MANNAN-BINDING LECTIN SERINE PROTEASE 2 (MANNOSE-BINDING PROTEIN-ASSOCIATED SERINE PROTEASE 2, EC=3.4.21.104) HUMAN MONOCLONAL ANTIBODY .GAMMA.4 HEAVY CHAIN, IMMUNOGLOBULIN G4 (226-PROLINE), ANTI-(HUMAN MANNAN-BINDING LECTIN-ASSOCIATED SERINE PROTEASE 2) (HUMAN MONOCLONAL OMS721 .GAMMA.4-CHAIN), DISULFIDE WITH HUMAN MONOCLONAL OMS721 .LAMBDA.-CHAIN, DIMER
  9. Drug

    (2R)-2-[(1R)-1-[[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-2-oxoethyl]-5-methylidene-2H-1,3-thiazine-4-carboxylic acid

    go.drugbank.com/drugs/DB08375
    Experimental

    Synonyms: (2R)-2-[(1R)-1-[[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-2-oxoethyl]-5-methylidene-2H-1,3-thiazine-4-carboxylic acid
  10. Drug

    AVID-200

    go.drugbank.com/drugs/DB18454
    Investigational

    AVID-200 is an Anti-transforming growth factor beta (TGF-β) trap fusion protein.

    Synonyms: Tgf-.beta. ligand trap comprised of tgf-.beta. receptor ectodomains fused to a human fc domain (avid-200), Tgf-beta 1/3 inhibitor avid200