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Indomethacin
go.drugbank.com/drugs/DB00328ApprovedInvestigationalAlthough deemed effective in reducing ocular inflammation in clinical studies, topical NSAIDs were also associated with a potential reduction in corneal sensitivity accompanied by an increased risk of … Indometacin was first discovered in 1963 and it was first approved for use in the U.S. by the Food and Drug Administration in 1965, [A486] along with other acetic acid derivatives such as [diclofenac]
Mixtures: INDAFLEX-IBCategories: indometacin and antiinfectives, Acetic Acid Derivatives and Related SubstancesPrednisone
go.drugbank.com/drugs/DB00635ApprovedInvestigationalVet approved[A187463] It is biologically inert and converted to [prednisolone] in the liver.[L10502] Prednisone was granted FDA approval on 21 February 1955.[L10496]
Categories: Alimentary Tract and Metabolism, Prednisolone and ProdrugsProducts: PREDNISON 10MG GALEN, PREDNISONA MK 50 MG TABLETASLamotrigine
go.drugbank.com/drugs/DB00555ApprovedInvestigationalLamotrigine is an antiepileptic drug belonging in the phenyltriazine class. It is used in the treatment of both epilepsy and as a mood stabilizer in bipolar disorder. … While it is indicated for epilepsy and bipolar disorders, there is evidence that lamotrigine could have some clinical efficacy in certain neuropathic pain states.[A849,A850]
Categories: Calcium-Regulating Hormones and AgentsProducts: LAMITOR 25MG TABLET, LAMOTRIGIN ACIS 25MGOxaliplatin
go.drugbank.com/drugs/DB00526ApprovedInvestigational[A796,A797] This is an effective combination treatment both as a first-line treatment and in patients refractory to an initial fluorouracil and leucovorin combination. … [A797] Oxaliplatin was approved by the FDA on January 9, 2004 and is currently marketed by Sanofi-Aventis under the trademark Eloxatin®.[L47316]
Categories: Antineoplastic and Immunomodulating AgentsSynonyms: (SP-4-2-(1R-TRANS))-(1,2-CYCLOHEXANEDIAMINE-N,N')(ETHANEDIOATO(2-)-O,O')PLATINUMProcainamide
go.drugbank.com/drugs/DB01035ApprovedA derivative of procaine with less CNS action.
Categories: Benzamides and benzamide derivatives, Antiarrhythmics, Class ISynonyms: p-Amino-N-(2-diethylaminoethyl)benzamideHydrocortisone succinate
go.drugbank.com/drugs/DB14545ApprovedInvestigationalCategories: Hydrocortisone and derivatives, Hormones, Hormone Substitutes, and Hormone AntagonistsProducts: A-hydrocort Inj 250mg/2ml, A-hydrocort Inj 500mg/4mlMoroctocog alfa
go.drugbank.com/drugs/DB13999ApprovedMoroctocog alfa is approved by Health Canada and by the European Medicines Agency for the control and prevention of hemorrhagic episodes and for routine and surgical prophylaxis in patients with hemophilia … Moroctocog alfa is identical in sequence to endogenously produced Factor VIII, but does not contain the B-domain, which has no known biological function.
Categories: Amino Acids, Peptides, and ProteinsProducts: Xyntha 250 IU Powder and Solvent for Solution for Injection, Xyntha 1000 IU Powder and Solvent for Solution for InjectionZirconium (89Zr) crefmirlimab berdoxam
go.drugbank.com/drugs/DB19157InvestigationalSynonyms: Iab22m2c (antibody fragment against the human cd8-antigen on cd8-positive t-cells, conjugated to the chelator desferrioxamine (df) and labeled with the radioisotope zirconium Zr-89)Human immunoglobulin G
go.drugbank.com/drugs/DB00028ApprovedInvestigationalIVIg is used in the treatment of immunodeficiencies, as well as autoimmune and inflammatory disorders. … IgG subclasses are fully represented in the following proportions: 70.3% IgG1, 24.7% IgG2, 3.1% IgG3, and 1.9% IgG4.
Mixtures: Iveegam Immuno 5000mg (iv)Categories: Amino Acids, Peptides, and ProteinsDobutamine
go.drugbank.com/drugs/DB00841ApprovedInvestigationalIt is proposed as a cardiotonic after myocardial infarction or open heart surgery.
Mixtures: Dobutamine Hydrochloride in DextroseCategories: Adrenergic and Dopaminergic Agents, Compounds used in a research, industrial, or household setting