Search
Potassium cation
go.drugbank.com/drugs/DB01345ApprovedPotassium is the major cation (positive ion) inside animal cells, while sodium is the major cation outside animal cells. … The concentration differences of these charged particles causes a difference in electric potential between the inside and outside of cells, known as the membrane potential.
Synonyms: potassium(1+), potassium(1+) ionMixtures: Telom-X-geneCefmenoxime
go.drugbank.com/drugs/DB00267ApprovedIt is reported to exhibit high activity against a wide variety of gram-positive and gram-negative bacteria. … Cefmenoxime is a novel broad-spectrum and third-generation cephalosporin antibiotic that is typically used in the treatment of female gynecologic and obstetric infections.
Synonyms: (6R,7R)-7-[[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, (6R,7R)-7-((Z)-2-(2-Amino-4-thiazolyl)-2-methoxyiminoacetamido)-3-((1-methyl-1H-5-tetraazolylthio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-2-carbonsaeureCategories: Heterocyclic Compounds, 2-RingCrotalus scutulatus antivenin
go.drugbank.com/drugs/DB13891ApprovedIt is intravenously administered to limit systemic toxicity [FDA label], [L2857], [L2858]. … Crotalus scutulatus antivenin is derived and purified immunoglobulin fragments obtained from other domestic animals such as sheep previously immunized with Crotalus scutulatus (also known as the _Mojave
Didanosine
go.drugbank.com/drugs/DB00900ApprovedInvestigationalA dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by a hydrogen. … Didanosine is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA by binding to reverse transcriptase; ddI is then metabolized to dideoxyadenosine triphosphate, its putative
Categories: Heterocyclic Compounds, 2-RingSynonyms: 9-((2R,5S)-5-(hydroxymethyl)-tetrahydrofuran-2-yl)-1H-purin-6(9H)-one, 9-((2S,5R)-5-Hydroxymethyl-tetrahydro-furan-2-yl)-9H-purin-6-olFluorodopa (18F)
go.drugbank.com/drugs/DB13848ApprovedInvestigational[L12849] Fluorodopa F 18 PET is used adjunctly with other diagnostic investigations and serves primarily to visualize dopaminergic nerve terminals in the striatum.[L12849] … Fluorodopa F 18 is a fluorinated analog of [levodopa] used as a diagnostic agent for positron emission tomography (PET) in the evaluation of Parkinsonian syndromes.
Synonyms: L-6-(18F)Fluoro-DOPA, 6-Fluoro-(18F)-L-3,4-DihydroxyphenylalanineEnoxacin
go.drugbank.com/drugs/DB00467ApprovedA broad-spectrum 6-fluoronaphthyridinone antibacterial agent (fluoroquinolones) structurally related to nalidixic acid.
Synonyms: 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-1,8-naphthyridine-3-carboxylic acid, 1-Ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acidCategories: 4-Quinolones, Heterocyclic Compounds, 2-RingMecasermin
go.drugbank.com/drugs/DB01277ApprovedInvestigationalThe rhIGF-1 protein is synthesized in bacteria (E. coli) that have been modified by the addition of the gene for human IGF-1. … The amino acid sequence of the product is identical to that of endogenous human IGF-1.
Synonyms: VEXXON-IGF-1, Human somatomedin CCategories: Recombinant Human Insulin-like Growth Factor-1Fosphenytoin
go.drugbank.com/drugs/DB01320ApprovedInvestigationalFosphenytoin is a water-soluble phenytoin prodrug used only in hospitals for the treatment of epileptic seizures. It works by slowing down impulses in the brain that cause seizures. … Its main mechanism is to block frequency-dependent, use-dependent and voltage-dependent neuronal sodium channels, and therefore limit repetitive firing of action potentials.
Synonyms: (3-Phosphoryloxymethyl)phenytoinCategories: Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2C8 Substrates with a Narrow Therapeutic IndexIsavuconazole
go.drugbank.com/drugs/DB11633ApprovedInvestigationalThe prodrug formulation of isavuconazole is FDA- and EMA-approved and is marketed under the trade name Cresemba for the treatment of invasive aspergillosis and mucormycosis as oral or intravenous administration … It is proposed that the intravenous and oral dosing can be used interchangeably [L1482], without the need for a repeat loading dose when transitioning from an IV to an oral formulation [A32026].
Categories: P-glycoprotein inhibitors, Cytochrome P-450 CYP2B6 Inducers