DB13848ApprovedInvestigationalSmall molecule
Fluorodopa F 18 is a fluorinated analog of levodopa used as a diagnostic agent for positron emission tomography (PET) in the evaluation of Parkinsonian syndromes. Fluorodopa F 18 PET is... Fluorodopa F 18 PET is used adjunctly with other diagnostic investigations and serves primarily to visualize dopaminergic nerve terminals in the striatum.
- Mechanism
- Curator reviewed
Pharmacologically active on Aromatic-L-amino-acid decarboxylase
- Primary indication
- Fluorodopa F 18 is indicated for use with positron emission tomography (PET) to visualize dopaminergic nerve terminals in the striatum for the evaluation of adult patients with suspected Parkinsonian syndromes (PS).Curator reviewed · 1 structured indication
- Formula / weight
- C9H10FNO4 · 214.183 g/mol (avg)
- First approval
- United States, 2019
- Also known as
- 18F-DOPA · 6-Fluoro-(18F)-L-3,4-Dihydroxyphenylalanine · Fluorodopa F 18 · Fluorodopa F-18 · L-3,4-Dihydroxy-6-[18F]Fluorophenylalanine
Resolves to
Clinical / RWD
Structure
InChIKey
PAXWQORCRCBOCU-RPDRGXCHSA-NSMILESN[C@@H](CC1=CC(O)=C(O)C=C1[18F])C(O)=OTargets
Transporters
What you can answer from here — as of July 07, 2026
1Protein targetEach mapped to UniProt, with action and pharmacological actionListed above
1TransporterSubstrate / inhibitor direction, not just membershipListed above
Which drugs share a target with Fluorodopa (18F), and which of those have an active Phase 3 trial?
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