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Displaying results 2811 - 2820 of 10000 in total
  1. Drug

    DaxibotulinumtoxinA

    go.drugbank.com/drugs/DB17929
    ApprovedInvestigational

    [A261075, L47860] DaxibotulinumtoxinA was first approved by the FDA on September 8, 2022, for the temporary improvement of glabellar lines. … It is a botulinum toxin without accessory proteins purified from the bacterium _Clostridium botulinum_ type A,[L47840] the gram-positive anaerobic bacterium primarily present in soil.

    Categories: Botulinum Toxins, Type A
  2. Drug

    Linoleic acid

    go.drugbank.com/drugs/DB14104
    Approved

    Mixtures: SIMILAC ALIMENTUM 400 G TOZ, Evening Primrose Oil Cap 500mg W Vit ECategories: Fatty Acids, Omega-6
  3. Drug

    Pectin

    go.drugbank.com/drugs/DB11158
    ApprovedInvestigationalVet approved

    Pectin is a heteropolysaccharide commercially derived from the cell wall of higher plants.[A32327] It is composed of partially methylated polygalacturonic acid units linked in the positions 1-4. … Under the FDA regulation, pectin qualifies as a GRAS (generally recognized as safe) food substance. This status allows pectin to be used with no limitations.[L1960]

    Mixtures: STREPTOMAGMA TABLET, 20 ADET, MGC HealthCategories: Compounds used in a research, industrial, or household setting
  4. Drug

    Eldecalcitol

    go.drugbank.com/drugs/DB05295
    Investigational

    Eldecalcitol (ED-71), a vitamin D analog, is a more potent inhibitor of bone resorption than alfacalcidol in an estrogen-deficient rat model of osteoporosis.

    Synonyms: 1α,25-dihydroxy-2β-(3-hydroxypropoxy)cholecalciferolCategories: Vitamin D and Analogues
  5. Drug

    Xanthine

    go.drugbank.com/drugs/DB02134
    Investigational

    (Dorland, 28th ed) … A purine base found in most body tissues and fluids, certain plants, and some urinary calculi.

    Mixtures: NECROTON CONCENTRADO 30 MG, ATOXCYNAROL® INYECTABLECategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates
  6. Drug

    Istradefylline

    go.drugbank.com/drugs/DB11757
    ApprovedInvestigational

    [L8237] This drug was first approved in Japan on 25 March 2013.[A184067] Istradefylline was granted FDA approval on 27 August 2019.[L8213] … Istradefylline, or KW6002, was developed by Kyowa Hakko Kirin in Japan for the treatment of Parkinson's disease as an adjunct to standard therapy.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A1 Substrates
  7. Drug

    Maridebart Cafraglutide

    go.drugbank.com/drugs/DB19339
    Investigational

    , With or Without Type 2 Diabetes Mellitus). … Maridebart Cafraglutide is under investigation in clinical trial NCT05669599 (Dose-ranging Study to Evaluate the Efficacy, Safety, and Tolerability of AMG 133 in Adult Subjects With Overweight or Obesity

    Synonyms: gamma1 heavy chain Homo sapiens (1-450) [VH (Homo sapiens IGHV3-33*01 (92.9%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.13] (26-33.51-58.97-109)) (1-120) -Homo sapiens IGHG1*03v, G1m3>G1m17, nG1m1 CH1 K120, Immunoglobulin G1, anti-(glucose-dependent insulinotropic polypeptide receptor) [275-cysteine,295-cysteine,300-glycine,305-cysteine] (human γ1-chain), disulfide with human κ-chain, dimer, 275,275′-bis(
  8. Drug

    STX-100

    go.drugbank.com/drugs/DB16334
    Investigational

    STX-100 is under investigation in clinical trial NCT01371305 (STX-100 in Patients With Idiopathic Pulmonary Fibrosis (IPF)).

  9. Drug

    Tarlatamab

    go.drugbank.com/drugs/DB17256
    ApprovedInvestigational

    Tarlatamab is a first-in-class T-cell engager used to treat extensive-stage small cell lung cancer. … [L50748] It is a bispecific monoclonal antibody that targets CD3 expressed on the surface of T-cells and delta-like ligand 3 (DLL3), an inhibitory ligand that suppresses Notch signaling and is highly expressed

    Synonyms: Immunoglobulin scfv-scfv-scfc, anti-(homo sapiens dll3 (delta-like ligand 3)) and anti-(homo sapiens cd3e (cd3 epsilon, leu-4)), monoclonal antibody single chain (scfv)2-scfc, bispecific
  10. Drug

    Bromchlorenone

    go.drugbank.com/drugs/DB20459
    Experimental

    Bromchlorenone is a small molecule drug. The usage of the INN stem '-renone' in the name indicates that Bromchlorenone is a mineralocorticoid receptor (MR, MCR, aldosterone receptor) antagonist. … Bromchlorenone has a monoisotopic molecular weight of 246.9 Da.