Explore a selection of our essential drug information below, or:
Identification
- Brand Names
- Luden's Drops, Sucrets
- Generic Name
- Pectin
- DrugBank Accession Number
- DB11158
- Background
Pectin is a heteropolysaccharide commercially derived from the cell wall of higher plants.2 It is composed of partially methylated polygalacturonic acid units linked in the positions 1-4.7 The carboxylic group of the constituents of pectin can exist in the form of esters, free acids, ammonium, potassium or sodium salts or as acid amides. Under the FDA regulation, pectin qualifies as a GRAS (generally recognized as safe) food substance. This status allows pectin to be used with no limitations.6
- Type
- Biotech
- Groups
- Approved, Investigational, Vet approved
- Synonyms
- Pectin
- External IDs
- E-440
Pharmacology
- Indication
Pectin is used in food as a gelling agent and stabilizer. As a medical drug, it has obtained a great interest in its potential use as a source of dietary fiber, lipid, cholesterol, serum glucose and insulin level lowering effect, gastric emptying delay.2 Some recent studies have researched the possibility of using pectin for the formation of nanoparticles as a delivery vehicle of drugs.3
Reduce drug development failure ratesBuild, train, & validate machine-learning modelswith evidence-based and structured datasets.Build, train, & validate predictive machine-learning models with structured datasets.- Associated Conditions
Indication Type Indication Combined Product Details Approval Level Age Group Patient Characteristics Dose Form Used in combination to treat Bacterial diarrhoea Combination Product in combination with: Furazolidone (DB00614), Kaolin (DB01575) •••••••••••• •••••••••• Used in combination to treat Diarrhea caused by salmonella Combination Product in combination with: Kaolin (DB01575), Furazolidone (DB00614) •••••••••••• •••••••••• Used in combination to treat Diarrhea caused by shigella Combination Product in combination with: Furazolidone (DB00614), Kaolin (DB01575) •••••••••••• •••••••••• Used in combination to treat Diarrhea caused by staphylococcus Combination Product in combination with: Furazolidone (DB00614), Kaolin (DB01575) •••••••••••• •••••••••• Used in combination to treat Escherichia coli diarrhea Combination Product in combination with: Furazolidone (DB00614), Kaolin (DB01575) •••••••••••• •••••••••• - Contraindications & Blackbox Warnings
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Pectin increases viscosity and volume of stools which helps it to be used for constipation and diarrhea.5 It is reported as well to present lowering effects of different body components. This effect depends on the type of pectin which indicated that this effect is related to the composition of the correspondent pectin. Nonetheless, this data is still unclear and more studies need to be performed to conclude this effect of pectin.4
- Mechanism of action
Pectin is an adsorbent that binds to bacteria, toxins and other irritants in the intestinal mucosa. Pectin is able to decrease the pH in the intestinal lumen and provides a soothing effect on the irritated mucosa.5
- Absorption
Pectin is not absorbed and it is not distributed in the body.5
- Volume of distribution
Pharmacokinetic studies have not been performed as pectin is not absorbed.
- Protein binding
Pharmacokinetic studies have not been performed as pectin is not absorbed.
- Metabolism
Pectin is depolymerized and de-esterified to a very small extent. It passes to the small intestine as a macromolecule and the majority of the pectin is eliminated unchanged.8
- Route of elimination
Pectin is completely excreted in the feces, including a small amount of trigalacturonic acid that can be found in the colon.5
- Half-life
Pharmacokinetic studies have not been performed as pectin is not absorbed.
- Clearance
Pharmacokinetic studies have not been performed as pectin is not absorbed.
- Adverse Effects
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Pectin is a substance determined to be safe.
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- No interactions found.
Products
Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.- Over the Counter Products
Name Dosage Strength Route Labeller Marketing Start Marketing End Region Image Berry Breezer Throat Drop Lozenge 7 mg/1 Oral Topco Associates LLC 2013-03-22 Not applicable US 
Berry Breezer Throat Drops Lozenge 7 mg/1 Oral Dollar General Corporation 2016-03-22 Not applicable US Berry Breezer Throat Drops Lozenge 7 mg/1 Oral CVS Health 2015-05-18 Not applicable US Berry Breezer Throat Relief Drop Lozenge 7 mg/1 Oral Family Dollar 2018-01-25 Not applicable US Berry Soother Throat Drops Lozenge 7 mg/1 Oral Meijer Distribution Inc 2018-07-13 Not applicable US - Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image AKITA Pectin (50 mg) + Attapulgite (600 mg) Tablet Ifars Pharmaceutical Laboratories 2014-02-17 2024-12-10 Indonesia 
ANTAMEN Pectin (22 mg/5ml) + Kaolin (986 mg/5ml) Suspension Oral Candra Nusantara Jaya 2015-05-13 2025-05-13 Indonesia ARCAPEC Pectin (50 mg) + Attapulgite (600 mg) Tablet Meprofarm 2018-06-06 2025-08-23 Indonesia ARCAPEC Pectin (50 mg/5ml) + Attapulgite (600 mg/5ml) Suspension Meprofarm 2016-12-27 2026-12-30 Indonesia ATAGIP Pectin (50 mg) + Attapulgite (600 mg) Tablet First Medipharma 2018-10-19 2025-08-23 Indonesia - Unapproved/Other Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image Herbon Banana Man Goodypops Pectin (10 mg/1) + Echinacea purpurea (50 mg/1) Lozenge Oral Purity Life Division of SunOpta 2009-09-30 2010-12-31 US Herbon Berry Buddies Pectin (10 mg/1) + Echinacea purpurea (50 mg/1) Lozenge Oral Purity Life Division of SunOpta 2009-09-30 2010-12-31 US Herbon Rockhopper Orange Goodypop Pectin (10 mg/1) + Echinacea purpurea (6.82 mg/1) Lozenge Oral Purity Life Division of SunOpta 2009-09-30 2010-12-31 US Herbon Rockhopper Strawberry Goodypop Pectin (10 mg/1) + Echinacea purpurea (6.82 mg/1) Lozenge Oral Purity Life Division of SunOpta 2009-09-30 2010-12-31 US
Categories
- ATC Codes
- A07BC01 — Pectin
- Drug Categories
- Alimentary Tract and Metabolism
- Antidiarrheals, Intestinal Antiinflammatory/antiinfective Agents
- Biological Products
- Biopolymers
- Carbohydrates
- Complex Mixtures
- Compounds used in a research, industrial, or household setting
- Diet, Food, and Nutrition
- Food
- Food Additives
- Food Ingredients
- Intestinal Adsorbents
- Macromolecular Substances
- Physiological Phenomena
- Plant Extracts
- Plant Preparations
- Polymers
- Polysaccharides
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 89NA02M4RX
- CAS number
- 9000-69-5
References
- General References
- Thakur BR, Singh RK, Handa AK: Chemistry and uses of pectin--a review. Crit Rev Food Sci Nutr. 1997 Feb;37(1):47-73. [Article]
- Wikiera A, Irla M, Mika M: [Health-promoting properties of pectin]. Postepy Hig Med Dosw (Online). 2014 Jan 2;68:590-6. doi: 10.5604/17322693.1102342. [Article]
- Verma AK, Kumar A: Pharmacokinetics and biodistribution of negatively charged pectin nanoparticles encapsulating paclitaxel. Cancer Nanotechnol. 2013;4(4-5):99-102. doi: 10.1007/s12645-013-0041-8. Epub 2013 Jun 12. [Article]
- Brouns F, Theuwissen E, Adam A, Bell M, Berger A, Mensink RP: Cholesterol-lowering properties of different pectin types in mildly hyper-cholesterolemic men and women. Eur J Clin Nutr. 2012 May;66(5):591-9. doi: 10.1038/ejcn.2011.208. Epub 2011 Dec 21. [Article]
- Kluwer W. (2008). Clinical pharmacology made incredibly easy (3rd ed.). Lippincott, Williams & Wilkins.
- FDA regulations [Link]
- Dissolutiontech [Link]
- ScienceDirect [Link]
- External Links
- MSDS
- Download (47.3 KB)
Clinical Trials
- Clinical Trials
Clinical Trial & Rare Diseases Add-on Data Package
Explore 4,000+ rare diseases, orphan drugs & condition pairs, clinical trial why stopped data, & more. Preview package Phase Status Purpose Conditions Count Start Date Why Stopped 100+ additional columns Unlock 175K+ rows when you subscribe.View sample dataNot Available Completed Diagnostic Helicobacter Pylori Infection 1 somestatus stop reason just information to hide Not Available Not Yet Recruiting Treatment The Eradication Rate of Helicobacter Pylori 1 somestatus stop reason just information to hide Not Available Terminated Treatment Oral Lichen Planus 1 somestatus stop reason just information to hide 4 Completed Treatment Bismuth / Gastric Cancer / Helicobacter Pylori Infection 2 somestatus stop reason just information to hide 4 Completed Treatment Gastroesophageal Reflux 1 somestatus stop reason just information to hide
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Suspension Suspension Oral 1 g/5ml Suspension Oral 6000 mg/30ml Lozenge Oral 7 mg/1 Lozenge Oral 10.5 mg/1 Lozenge Oral 12 mg/1 Tablet Oral Capsule Oral Lozenge Oral Liquid Oral Suspension Oral Lozenge Oral 5.4 mg/1 Lozenge Oral 11.5 mg/7g Lozenge Oral 2.8 mg/1 Paste Oral; Topical Solution Oral Tablet Lozenge Oral 2 mg/1 Lozenge Oral 1.7 mg/1 Lozenge Oral 0.1 g/100g Lozenge Oral 3.8 mg/1 Lozenge Oral 5 mg/4.2g Lozenge Oral 10 mg/1 Suspension Oral 10.0000 g Lozenge Oral 11.5 mg/1 - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Liquid
- Experimental Properties
Property Value Source melting point (°C) 6.1ºC 'MSDS' boiling point (°C) 415.5ºC at 760 mmHg 'MSDS' water solubility Partially soluble in cold water 'MSDS'
Drug created at December 03, 2015 16:51 / Updated at July 13, 2021 09:51