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Methylcellulose
go.drugbank.com/drugs/DB11228ApprovedInvestigationalMethyl cellulose is a hydrophilic white powder in pure form and dissolves in cold (but not in hot) water, forming a clear viscous solution or gel. … The Degree of Substitution (DS) of a given form of methyl cellulose is defined as the average number of substituted hydroxyl groups per glucose with a theoretical maximum of 3, however more typical values
Tyrothricin
go.drugbank.com/drugs/DB13503ApprovedWithdrawnTyrothricin is an antibiotic peptide complex produced and extracted from the aerobic Gram-positive bacillus Brevibacillus parabrevis [L4019, L4021, A32851] which was previously categorized as Bacillus … Nevertheless, as tyrothricin is both cytolytic and hemolytic, it does demonstrate systemic toxicity [L4019, L4021, L4022], although certain formulations that are safe for human use like throat lozenges do
Olaparib
go.drugbank.com/drugs/DB09074ApprovedInvestigational[A246015] Olaparib is used to treat a number of BRCA-associated tumours, including ovarian cancer, breast cancer, pancreatic cancer, and prostate cancer. … [L41100, L40908, L43792] It was first approved by the FDA and EU in December 2014,[A246020] and by Health Canada in April 2016.[L42820]
Susoctocog alfa
go.drugbank.com/drugs/DB11606ApprovedInvestigationalIt is the first recombinant porcine FVIII treatment approved for AHA that allows physicians to manage the treatment's efficacy and safety by measuring factor VIII activity levels in addition to clinical … The recombinant porcine sequence allows less susceptibility to inactivation by circulating human factor VIII antibodies.
Hyaluronidase (human recombinant)
go.drugbank.com/drugs/DB06205ApprovedInvestigational[A199026] Hyaluronidase has been used in surgical settings for at least the past 60 years to improve the diffusion of local anesthetics. … [A4033] Hyaluronidase is an enzyme used to improve the absorption and dispersion of parenterally administered fluids, drugs, and contrast agents.
Daridorexant
go.drugbank.com/drugs/DB15031ApprovedInvestigational[A244225] It was approved by the FDA on January 10, 2022, under the name QUVIVIQ.[L39660] as the second orexin receptor antagonist approved to treat insomnia following [suvorexant]. … [A244225] Daridorexant works on orexin receptors OX1R and OX2R to block the binding of orexins, which are wake-promoting neuropeptides and endogenous ligands to these receptors.
Medium-chain triglycerides
go.drugbank.com/drugs/DB13959ApprovedInvestigationalIn the body, MCTs are broken down into glycerol and free fatty acids, which are directly absorbed into the blood stream and transported to the target organs to exert a range of biological and metabolic … Medium-chain triglycerides (MCTs) are triglycerides made up of a glycerol backbone and three fatty acids with an aliphatic tail of six to 12 carbon atoms.
Mixtures: SmofKabiven N-Plus zentral Emulsion zur Infusion, SmofKabiven N-Plus zentral elektrolytfrei Emulsion zur InfusionSomatrogon
go.drugbank.com/drugs/DB14960ApprovedInvestigationalIt is a chimeric product generated by fusing three copies of the C-terminal peptide (CTP), or 28 carboxy-terminal residues, from the beta chain of human chorionic gonadotropin (hCG) to the N-terminus and … growth hormone caused by growth hormone deficiency, marking Canada as the first country to approve this drug.
Synonyms: .)-(118-145)-PEPTIDE (1-28) WITH HUMAN SOMATOTROPIN (GROWTH HORMONE, GH) (29-219) AND TWO TANDEM COPIES OF HUMAN CHORIOGONADOTROPIN SUBUNIT .BETA. (CG-.BETA.)-(118-145)- PEPTIDE (220-247Cisapride
go.drugbank.com/drugs/DB00604ApprovedWithdrawnIn many countries (including Canada) cisapride has been either withdrawn or has had its indications limited due to reports about long QT syndrome due to cisapride, which predisposes to arrhythmias. … The FDA issued a warning letter regarding this risk to health care professionals and patients.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeTocopherol
go.drugbank.com/drugs/DB11251ApprovedInvestigationalThey present strong antioxidant activities, and it is determined as the major form of vitamin E.