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Displaying results 2841 - 2850 of 3888 in total
  1. Drug

    Reclazepam

    go.drugbank.com/drugs/DB21411
    Experimental

    The usage of the INN stem '-azepam' in the name indicates that Reclazepam is a diazepam derivative. Reclazepam has a monoisotopic molecular weight of 373.04 Da.

  2. Drug

    Metoxepin

    go.drugbank.com/drugs/DB21433
    Experimental

    The usage of the INN stem '-oxepin' in the name indicates that Metoxepin is a tricyclic compound. Metoxepin has a monoisotopic molecular weight of 322.17 Da.

  3. Drug

    Davelizomib

    go.drugbank.com/drugs/DB21660
    Experimental

    The usage of the INN stem '-zomib' in the name indicates that Davelizomib is a proteasome inhibitor. Davelizomib has a monoisotopic molecular weight of 481.18 Da.

  4. Target

    Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

    go.drugbank.com/bio_entities/BE0000176
    TargetEnzymeHumans

    Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone

    Synonyms: Flavoprotein subunit of complex II
  5. Target

    NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7

    go.drugbank.com/bio_entities/BE0000512
    TargetHumans

    Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. … Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone

    Synonyms: Complex I-B18
  6. Drug

    UCB7362

    go.drugbank.com/drugs/DB17096
    Experimental

    It has shown high potency in biochemical (IC<sub>50</sub> = 7 nM), _in vitro_ (_P. falciparum_ 3D7 lactate dehydrogenase growth inhibition assay IC<sub>50</sub> = 10 nM), and _in vivo_ (50 mg/kg dose

  7. Drug

    Calcifediol

    go.drugbank.com/drugs/DB00146
    ApprovedInvestigationalNutraceutical

    The major circulating metabolite of vitamin D3 (cholecalciferol). It is produced in the liver and is the best indicator of the body's vitamin D stores. It is effective in the treatment of rickets and osteomalacia, both in azotemic and no...

    Categories: Sex Hormones and Insulins
  8. Drug

    Acetohexamide

    go.drugbank.com/drugs/DB00414
    ApprovedWithdrawn

    A sulfonylurea hypoglycemic agent that is metabolized in the liver to 1-hydrohexamide. Acetohexamide has been discontinued in the US market.

    Categories: Genito Urinary System and Sex Hormones
  9. Drug

    Barnidipine

    go.drugbank.com/drugs/DB09227
    Investigational

    It does not produce reflex tachycardia [A7842]. … According to a dose-ranging, multicentre, placebo-controlled, double-blind study in patients with mild to moderate hypertension, the antihypertensive response from barnidipine treatment was maintained

  10. Drug

    Gestaclone

    go.drugbank.com/drugs/DB21090
    Experimental

    The usage of the INN stem '-clone' in the name indicates that Gestaclone is a hypnotic tranquillizer. Gestaclone has a monoisotopic molecular weight of 370.17 Da.