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Displaying results 2871 - 2880 of 10000 in total
  1. Drug

    Bacillus clausii

    go.drugbank.com/drugs/DB16537
    Investigational

    Products: Enterogermina 2 Billions/5 ml oral suspension
  2. Drug

    Amifampridine

    go.drugbank.com/drugs/DB11640
    Approved

    About 50-60% of the patients develop more rapidly progressive LEMS and small cell lung cancer, which influences the prognosis [A33863]. … It was demonstrated in clinical studies involving healthy volunteers that the pharmacokinetics and systemic exposure to amifampridine is affected by the genetic differences in N-acetyl-transferase (NAT

  3. Drug

    Oridonin

    go.drugbank.com/drugs/DB19086
    Investigational

    Oridonin is under investigation in clinical trial NCT05130892 (Effect of Inflammasome Inhibitor on Hscrp in Patients After PCI).

    Synonyms: Kaur-16-en-15-one, 7.alpha.,20-epoxy-1.alpha.,6.beta.,7,14-tetrahydroxy-, (14r)-, Kaur-16-en-15-one, 7,20-epoxy-1,6,7,14-tetrahydroxy-, (1.alpha.,6.beta.,7.alpha.,14r)-
  4. Drug

    Benzhydrocodone

    go.drugbank.com/drugs/DB15465
    Approved

    [L4894] It was developed in an effort to reduce parenteral bioavailability of the active metabolite as a deterrent to abuse. … It was first approved by the FDA in February 2018 in combination with [acetaminophen] under the trade name Apadaz, marketed by KVK Tech and developed by KemPharm.[L7859,L7862]

  5. Drug

    PG-530742

    go.drugbank.com/drugs/DB05495
    Investigational

    Studies are currently assessing the efficacy and safety of PG-530742 in the treatment of mild to moderate knee osteoarthritis. … By inhibiting these MMPs, it potentially limits cartilage degradation and disease progression.

  6. Drug

    Andrographolide

    go.drugbank.com/drugs/DB05767
    Investigational

    Andrographolide (HMPL-004) is a botanical product extracted from a herb that occurs naturally in China. The herb has an extensive history of use in TCM for the treatment of upper respiratory tract infections and other inflammatory and in...

    Synonyms: 3α,14,15,18-tetrahydroxy-5b,9bH,10a-labda-8(20),12-dien-16-oic acid γ-Lactone
  7. Drug

    L-3972-T

    go.drugbank.com/drugs/DB17441
    Experimental

    L-3972-T is one of the components of the human papilloma virus (HPV) type 16 E6/E7 synthetic long peptide (SLP) vaccine ISA101b.

    Synonyms: Human Papilloma Virus (HPV) Type 16 E6/E7 Synthetic Long Peptide (SLP) Vaccine Component L-3972-T, ISA101B component L-3972-T
  8. Drug

    Birch bark extract

    go.drugbank.com/drugs/DB16536
    ApprovedInvestigational

    [L42380] Two oleogel formulations of birch bark extract (Oleogel-S10, 10% of triterpene dry extract in sunflower oil) have been approved by the European Medicines Agency. … [L42390] Filsuvez was subsequently approved for the same indication by the US FDA in December 2023.

    Categories: Cytochrome P-450 CYP2C8 Inhibitors, Cytochrome P-450 Enzyme Inhibitors
  9. Drug

    Dextropropoxyphene

    go.drugbank.com/drugs/DB00647
    ApprovedIllicitWithdrawn

    Due to the risk of cardiac arrhythmias and overdose, possibly leading to death, dextropropoxyphene has been withdrawn from the market in Europe and the United States. … The levo-isomer appears to exhibit a very limited antitussive effect.

    Mixtures: Darvocet-N 100, Darvocet-N 50Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Cytochrome P-450 Substrates
  10. Drug

    Amprolium

    go.drugbank.com/drugs/DB11374
    ExperimentalVet approved

    Amprolium is a coccidiostat used in poultry.

    Synonyms: 1-((4-amino-2-Propyl-5-pyrimidinyl)methyl)-2-picolinium chlorideProducts: AMPRO 200mg/ml Oral Solution, AMPROLOX 20% Powder