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Canertinib
go.drugbank.com/drugs/DB05424InvestigationalCanertinib is a pan-erbB tyrosine kinase inhibitor which work against esophageal squamous cell carcinoma in vitro and in vivo. … Canertinib treatment significantly affects tumour metabolism, proliferation and hypoxia as determined by PET.
Categories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 1-RingHyoscyamine
go.drugbank.com/drugs/DB00424ApprovedInvestigational[A228713] Hyoscyamine is used for a wide variety of treatments and therapeutics due to its antimuscarinic properties. … Hyoscyamine is a tropane alkaloid and the levo-isomer of [atropine].[A228423] It is commonly extracted from plants in the _Solanaceae_ or nightshade family.
Mixtures: Uro-L, Urin D/SSynonyms: L-Hyoscyamine, L-Tropine tropateNaltrexone
go.drugbank.com/drugs/DB00704ApprovedInvestigationalVet approvedIt is a narcotic antagonist that is effective orally, longer lasting and more potent than naloxone, and has been proposed for the treatment of heroin addiction. … Derivative of noroxymorphone that is the N-cyclopropylmethyl congener of naloxone.
Mixtures: Troxyca ER, Troxyca ERCategories: Heterocyclic Compounds with 4 or More RingsCobicistat
go.drugbank.com/drugs/DB09065ApprovedInvestigationalAlthough it does not have any anti-HIV activity, cobicistat acts as a pharmacokinetic enhancer by inhibiting cytochrome P450 3A isoforms (CYP3A) and therefore increases the systemic exposure of coadministered … Increasing systemic exposure of anti-retrovirals (ARVs) without increasing dosage allows for better treatment outcomes and a decreased side effect profile.
Mixtures: Prezcobix Ped, PREZCOBIX® TABLETAS RECUBIERTASCategories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesRiltozinameran
go.drugbank.com/drugs/DB17095ApprovedInvestigationalBA.4, BA.5) which, although similar, may behave differently from one another.[L43917] Riltozinameran is an mRNA vaccine encoding the S glycoprotein of SARS-CoV-2 Omicron variant lineage BA.1. … The Omicron variant of SARS-CoV-2 is a variant of concern that was first reported in November 2021.
Mixtures: Comirnaty Original/omicron Ba.1Piperacillin
go.drugbank.com/drugs/DB00319ApprovedInvestigationalSemisynthetic, broad-spectrum, ampicillin derived ureidopenicillin antibiotic proposed for pseudomonas infections. It is also used in combination with other antibiotics.
Mixtures: KABICTAM® POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE, PIPERACILINA 4G + TAZOBACTAM 0.5G POLVO ESTERIL PARA RECONSTITUIR A SOLUCION INYECTABLECategories: Penicillin G, Heterocyclic Compounds, 2-RingMagnesium gluconate
go.drugbank.com/drugs/DB13749ApprovedWithdrawnMagnesium gluconate is a magnesium salt of gluconate. It demonstrates the highest oral bioavailability of magnesium salts [L2608] and is used as a mineral supplement. … Magnesium is ubiquitous in the human body, and is naturally present in many foods, added to other food products, available as a dietary supplement and used as an ingredient in some medicines (such as antacids
Mixtures: K-med, Formula 9 TabSynonyms: Magnesium D-gluconate (1:2) dihydrate, Magnesium D-gluconate (1:2) hydrateRimegepant
go.drugbank.com/drugs/DB12457ApprovedInvestigational[L38814] The current standard of migraine therapy involves abortive treatment with "triptans", such as [sumatriptan], but these medications are contraindicated in patients with pre-existing cerebrovascular
Categories: MATE 1 Inhibitors, P-glycoprotein substratesFormic acid
go.drugbank.com/drugs/DB01942ApprovedInvestigationalIt is commonly used as a preservative and antibacterial agent in livestock feed.
Mixtures: Pre-Tabs DHA Prenatal Multi-vitamin/Mineral Supplement with DHA/EPA, V-NatalCER-001
go.drugbank.com/drugs/DB18538InvestigationalCER-001 is a negatively charged lipoprotein particle comprising human recombinant apolipoprotein A-I and two phospholipids: sphingomyelin and dipalmitoylphosphatidylglycerol.
Categories: Apolipoproteins ASynonyms: Recombinant human apolipoprotein A-I/phospholipid complexes