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Displaying results 2881 - 2890 of 10000 in total
  1. Drug

    Sipavibart

    go.drugbank.com/drugs/DB21908
    ApprovedInvestigational

    Sipavibart is a recombinant human IgG1 monoclonal antibody that is long-acting. … [A274098] It works by binding to the SARS-CoV-2 spike protein receptor binding domain (RBD), neutralize the virus and preventing its entry into the host cell.

    Synonyms: Gamma1 heavy chain Homo sapiens (1-455) [VH (Homo sapiens IGHV3-9*01 (94.9%) -(IGHD) -IGHJ1*01 (90.9%) L123>T (120), CDR-IMGT [8.8.18] (26-33.51-58.97-114)) (1-125) -Homo sapiens IGHG1*03, G1m3, nG1m1, 1-chain), disulf
  2. Drug

    Pyrrolidine

    go.drugbank.com/drugs/DB16858
    Investigational

    Synonyms: 1-AzacyclopentaneCategories: Heterocyclic Compounds, 1-Ring
  3. Drug

    Citrulline

    go.drugbank.com/drugs/DB00155
    InvestigationalNutraceutical

    It is also produced from arginine as a by-product of the reaction catalyzed by NOS family. Its name is derived from citrullus, the Latin word for watermelon, from which it was first isolated. … Citrulline is an amino acid. It is made from ornithine and carbamoyl phosphate in one of the central reactions in the urea cycle.

    Synonyms: N(5)-(Aminocarbonyl)-L-ornithine, L-2-Amino-5-ureidovaleric acidProducts: STIMOL ORAL SOLUTION 1g/10ml
  4. Drug

    Namodenoson

    go.drugbank.com/drugs/DB12885
    Investigational

    Namodenoson has been used in trials studying the treatment of Chronic Hepatitis C and Hepatocellular Carcinoma.

    Categories: Heterocyclic Compounds, 2-Ring, Purinergic P1 Receptor AgonistsSynonyms: 2-Chloro-N(6)-(3-iodobenzyl)adenosine-5'-N-methyluronamide
  5. Drug

    Porphobilinogen

    go.drugbank.com/drugs/DB02272
    Experimental

    Porphobilinogen is a pyrrole involved in porphyrin metabolism. It is generated by the enzyme ALA dehydratase, and converted into hydroxymethyl bilane by the enzyme porphobilinogen deaminase.

    Synonyms: 5-(Aminomethyl)-4-(carboxymethyl)-1H-pyrrole-3-propionic acidCategories: Heterocyclic Compounds, 1-Ring
  6. Drug

    Tenalisib

    go.drugbank.com/drugs/DB15295
    Investigational

    Tenalisib is under investigation in clinical trial NCT03711604 (Compassionate Use Study of Tenalisib (RP6530)).

    Synonyms: 3-(3-FLUOROPHENYL)-2-((1S)-1-((7H-PURIN-6-YL)AMINO)PROPYL)-4H-1-BENZOPYRAN-4-ONE, 4H-1-BENZOPYRAN-4-ONE, 3-(3-FLUOROPHENYL)-2-((1S)-1-(9H-PURIN-6-YLAMINO)PROPYL)-Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  7. Drug

    Ruzinurad

    go.drugbank.com/drugs/DB19209
    Investigational

    Ruzinurad is under investigation in clinical trial NCT04956432 (A Multicentre, Randomized, Double-blind, Allopurinol Controlled Study to Evaluate the Efficacy and Safety of SHR4640 in Subjects With Gout

    Categories: Heterocyclic Compounds, 2-RingSynonyms: 1-((6-bromo-4-quinolinyl)thio)cyclobutanecarboxylic acid, Cyclobutanecarboxylic acid, 1-((6-bromo-4-quinolinyl)thio)-
  8. Drug

    BHV-5000

    go.drugbank.com/drugs/DB17817
    Experimental

    BHV-5000 is an orally bioavailable, low-trapping, potent N-methyl-D-aspartate (NMDA) receptor antagonist. The active metabolite of BHV-5000 is [lanicemine].[L46446]

    Synonyms: (S)-1-(L-valyl)-N_((S)-1-phenyl-2-(pyridin-2-yl)ethyl)pyrrolidine-2-carboxamide fumarate
  9. Drug

    Bersanlimab

    go.drugbank.com/drugs/DB17377
    Investigational

    Bersanlimab is an investigational monoclonal antibody directed against intercellular adhesion molecule 1 (ICAM-1).

    Synonyms: Anti-icam-1 monoclonal antibody bi-505, Immunoglobulin g1-lambda, anti-(homo sapiens icam1(intercellular adhesion molecule 1, icam-1, cd54)), human monoclonal antibody
  10. Drug

    Arginine glutamate

    go.drugbank.com/drugs/DB13207
    Investigational

    Synonyms: L-Arginine L-glutamate, 2-amino-5-(diaminomethylideneamino)pentanoic acidMixtures: NUTRIFLEX PLUS IN 1000ML TWIN FLEX, NUTRIFLEX PLUS IN 2000ML TWIN FLEX