Porphobilinogen

DB02272ExperimentalSmall molecule

Porphobilinogen is a pyrrole involved in porphyrin metabolism. It is generated by the enzyme ALA dehydratase, and converted into hydroxymethyl bilane by the enzyme porphobilinogen deaminase.

Mechanism: Pharmacologically active on Delta-aminolevulinic acid dehydratase
Curator reviewed
Formula / weight: C₁₀H₁₄N₂O₄ · 226.2292 g/mol (avg)

Resolves to

Compound

UNII74KHC72QXKCAS487-90-1ChEMBLCHEMBL1235151ChEBI17381PubChem1021KEGGC00931

Structure

InChIKeyQSHWIQZFGQKFMA-UHFFFAOYSA-NSMILESNCC1=C(CC(O)=O)C(CCC(O)=O)=CN1

Targets

P13716ALAD

What you can answer from here — as of September 19, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

2+ReferencesStructured and connected to the statements they support

Which drugs share a target with Porphobilinogen, and which of those have an active Phase 3 trial?

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