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Velusetrag
go.drugbank.com/drugs/DB12702InvestigationalIt is a highly selective serotonin receptor agonist effective in patients with chronic constipation. It is being developed by Theravance. … Velusetrag was discovered by Theravance through the application of its multivalent drug design in a research program dedicated to finding new treatments for GI motility disorders.
Osilodrostat
go.drugbank.com/drugs/DB11837ApprovedInvestigational[A191850] Osilodrostat was approved for use in the EU in January 2020 for the treatment of endogenous Cushing's syndrome (i.e. … Osilodrostat is manufactured by Novartis under the brand name Isturisa.
Categories: Sex Hormones and Insulins, Cytochrome P-450 SubstratesRhubarb
go.drugbank.com/drugs/DB10651ApprovedRhubarb allergenic extract is used in allergenic testing.
Mixtures: ORALDIN ÇÖZELTI ,10 ML-1 ŞIŞE, PIRALDYNE ORAL SOLUSYON 10 MLBB 21217
go.drugbank.com/drugs/DB17373InvestigationalBB 21217 is an anti-BCMA CAR T cell therapy that uses the same CAR molecule as [idecabtagene vicleucel] (bb2121), but adds the PI3K inhibitor bb007 during ex vivo culture to enrich the drug product (DP … ) for memory-like T cells.
Levomilnacipran
go.drugbank.com/drugs/DB08918ApprovedInvestigational[L47946] First approved by the FDA on July 25, 2013, levomilnacipran is used to treat major depressive disorder in adults. … Levomilnacipran is a selective serotonin and norepinephrine reuptake inhibitor (SNRI), although it is a more potent inhibitor of norepinephrine reuptake than serotonin reuptake.
Synonyms: CYCLOPROPANECARBOXAMIDE, 2-(AMINOMETHYL)-N,N-DIETHYL-1-PHENYL-, (1S,2R)-Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesDaleuton
go.drugbank.com/drugs/DB00154InvestigationalNutraceuticalA 20-carbon-chain fatty acid, unsaturated at positions 8, 11, and 14. It differs from arachidonic acid, 5,8,11,14-eicosatetraenoic acid, only at position 5.
Synonyms: 20:3, n-6,9,12 all-cis, (Z,Z,Z)-8,11,14-IcosatrienoateNomifensine
go.drugbank.com/drugs/DB04821ApprovedWithdrawnApproval of the NDA for Merital capsules was withdrawn on March 20, 1992 (see the Federal Register of March 20, 1992 (57 FR 9729)). Also withdrawn from the Canadian and UK markets. … FDA published a notice of its determination that Merital capsules were removed from the market for safety reasons (see the Federal Register of June 17, 1986 (51 FR 21981)).
Synonyms: D,L-nomifensine, 2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquinolin-8-ylamineCategories: Heterocyclic Compounds, 2-RingABP-700
go.drugbank.com/drugs/DB15411InvestigationalABP-700 is under investigation in clinical trial NCT02800590 (Study to Investigate the Safety and Efficacy of 3 Dosing Regimens of ABP-700 for Procedural Sedation in Adult Participants Undergoing Colonoscopy
Categories: GABA-A Receptor Agonists, Heterocyclic Compounds, 1-RingLS11
go.drugbank.com/drugs/DB05918InvestigationalLS11(talaporfin sodium) is an agent consisting of chlorin e6, derived from chlorophyll, and L-aspartic acid with photosensitizing activity. … After intratumoral activation by light emitting diodes, taporfin sodium forms an extended high energy conformational state that generates singlet oxygen, resulting in free radical-mediated cell death.
Dexamethasone acetate
go.drugbank.com/drugs/DB14649ApprovedInvestigationalVet approvedIn a June 16 2020 press release highlighting early results of a clinical trial, Randomized Evaluation of COVID-19 Therapy (RECOVERY), it was reported that dexamethasone reduced COVID-19 deaths by approximately … [A188724] Dexamethasone acetate has largely been replaced by [dexamethasone] phosphate and continues to be administered for a large variety of inflammatory conditions.
Mixtures: DUODECADRON ® SUSPENSIÓN INYECTABLE 1 ML, DUODECADRON ® SUSPENSIÓN INYECTABLE 1 MLCategories: Cytochrome P-450 CYP2A6 Inducers, Cytochrome P-450 Substrates