Dexamethasone acetate

DB14649ApprovedInvestigationalVet approvedSmall moleculeCorticosteroids

Commonly known as decadron, dexamethasone acetate is a glucocorticosteroid previously marketed in the USA for the treatment of inflammatory respiratory, allergic, autoimmune, and other conditions. Developed in 1957, dexamethasone is... Developed in 1957, dexamethasone is structurally similar to other corticosteroids such as hydrocortisone and prednisolone.

Mechanism: Pharmacologically active on Glucocorticoid receptor
Curator reviewed
Formula / weight: C₂₄H₃₁FO₆ · 434.4977 g/mol (avg)
Also known as: Dexamethasone 21-acetate

Resolves to

Compound

UNIIK7V8P532WPCAS1177-87-3ChEMBLCHEMBL1530428ChEBI4463PubChem236702KEGGD07796

Clinical / RWD

RxNorm22690

Structure

InChIKeyAKUJBENLRBOFTD-RPRRAYFGSA-NSMILES[H][C@@]12C[C@@H](C)[C@](O)(C(=O)COC(C)=O)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])CCC2=CC(=O)C=C[C@]12C

Targets

P04150NR3C1P04083ANXA1P35228NOS2P51843NR0B1O75469NR1I2

Transporters

O95342ABCB11P08183ABCB1Q92887ABCC2P46721SLCO1A2Q9UNQ0ABCG2Q8TCC7SLC22A8

What you can answer from here — as of June 04, 2026

5Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

6TransportersSubstrate / inhibitor direction, not just membership

Listed above

1,088Drug interactionsStructured to mechanism, not free text

13Clinical trialsPhase, status and sponsor resolved per trial

4Structured indicationsCondition, population, route and combination as fields, not prose

23Marketed productsAcross 3 countries and 11 labellers

80+ReferencesStructured and connected to the statements they support

Which drugs share a target with Dexamethasone acetate, and which of those have an active Phase 3 trial?

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