Search

Elagolix

It has been determined that endometriosis is one of the most common gynecologic disorders in the United States [A35868, A35869, F801]. … As of 24 July 2018, however, the U.S.

CHGN111

It was under investigation until approximately 2007. … Numerous parameters of mitochondrial function are altered when the activity of CLK-1 is reduced, which results in a decrease of ROS at critical cellular sites, as well as in a decrease of systemic oxidative

Ketobemidone

It also has some NMDA-antagonist properties. This makes it useful for some types of pain that don't respond well to other opioids.

Conestat alfa

It does this through inhibition of several target proteases within these pathways including activated C1s, kallikrein, factor XIIa and factor XIa. … C1 esterase inhibitor has also been shown to inhibit the action of thrombin within the coagulation pathway, and tPA and plasmin within the fibrinolytic pathway.

Bevantolol

Bevantolol is a beta-1 adrenoceptor antagonist that has been shown to be as effective as other beta blockers for the treatment of angina pectoris and hypertension. … Mechanism of Action Animal experiments confirm both agonist and antagonist effects on alpha-receptors, in addition to antagonist activity at beta-1 receptors.

Antipyrine

(From Martindale, The Extra Pharmacopoeia, 30th ed, p29) … An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver.

Lovotibeglogene autotemcel

[L49266] It was approved alongside [exagamglogene autotemcel] (Casgevy), another gene therapy, with the two treatments comprising the first cell-based gene therapies for the treatment of SCD in patients … lovotibeglogene autotemcel provides a functional copy of a modified beta-globin gene (β^A-T87Q-globin) that when combined with α-globin, produces hemoglobins with similar oxygen-binding capacity as

Tripelennamine

It is used to treat asthma; HAY fever; urticaria; and rhinitis; and also in veterinary applications. Tripelennamine is administered by various routes, including topically.

Fennel

Eteplirsen

Eteplirsen was the first treatment for DMD approved by the FDA.[A244925] … It consists of a six-membered morpholino ring replacing the five-membered ribofuranosyl rings found in natural DNA and RNA.