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Atenolol
go.drugbank.com/drugs/DB00335ApprovedInvestigational[A235850,A235855] A Cochrane review of patients being treated for primary hypertension shows that atenolol shows a risk ratio of 0.88 for cardiovascular disease risk and a risk ratio of 0.99 for mortality … Sir James Black, a Scottish pharmacologist, pioneered the use of beta-blockers for the management of angina pectoris in 1958 for which he received the Nobel Prize.
Mixtures: TENORETIC 100 MG/25 MG FILM TABLET, 28 ADET, TENORETIC 50 MG/12.5 MG FILM TABLET, 28 ADETCategories: Adrenergic beta-1 Receptor Antagonists, Antihypertensive Agents Indicated for HypertensionMeloxicam
go.drugbank.com/drugs/DB00814ApprovedInvestigationalVet approved[A190189] With a longer half-life than most other NSAIDS, it is a favorable option for those who require once-daily dosing. Meloxicam is available in oral, transdermal, and intravenous formulations. … It is a preferential COX-2 inhibitor, purportedly reducing the risk of adverse gastrointestinal tract effects, however, this is a topic of controversy.[A190198,A190201]
Mixtures: OCAM PROTECT 15 MG, MELOCAM DUO 7.5/20 MG TABLETAS RECUBIERTASCategories: Heterocyclic Compounds, 1-RingGentamicin
go.drugbank.com/drugs/DB00798ApprovedInvestigationalVet approvedGentamicin is a bactericidal aminoglycoside that was discovered and isolated from _Micromonospora purpurea_ in 1963. … [A234364] This synergistic activity is not only important for the treatment of complex infections, but can also contribute to dose optimization and reduced adverse effects.
International brands: G-MycinMixtures: GENTAMICIN POS, GENTAMICIN POSLeflunomide
go.drugbank.com/drugs/DB01097ApprovedInvestigationalLeflunomide is a pyrimidine synthesis inhibitor belonging to the DMARD (disease-modifying antirheumatic drug) class of drugs, which are chemically and pharmacologically very heterogeneous.
Categories: Heterocyclic Compounds, 1-RingProducts: Pro-leflunomide, ARAVA 10 MG FTAFormoterol
go.drugbank.com/drugs/DB00983ApprovedInvestigationalof action (12 hours) - for this reason, treatment guidelines for asthma recommend its use as both a reliever and maintenance medication. … Formoterol is an inhaled beta<sub>2</sub>-agonist used in the management of COPD and asthma that was first approved for use in the United States in 2001.
Synonyms: N-[2-hydroxy-5-(1-hydroxy-2-{[2-(4-methoxyphenyl)-1-methylethyl]amino}ethyl)phenyl]formamide, 2'-hydroxy-5'-(1-hydroxy-2-((p-methoxy-α-methylphenethyl)amino)ethyl)formanilideMixtures: FLUTIFORM® 250 MCG / 10 MCG, FLUTIFORM® 250 MCG / 10 MCGDabigatran etexilate
go.drugbank.com/drugs/DB06695ApprovedInvestigational[A177463] In contrast to warfarin, because its anticoagulant effects are predictable, lab monitoring is not necessary.[A177463] Dabigatran etexilate was approved by the FDA in 2010.[L6022]
Categories: Heterocyclic Compounds, 1-RingProducts: Dabigatranetexilat 1A Pharma 110 mg - Hartkapseln, Dabigatranetexilat 1A Pharma 150 mg - HartkapselnAmikacin
go.drugbank.com/drugs/DB00479ApprovedInvestigationalVet approved[FDA label] Amikacin is synthesized by acylation with the l-(-)-γ-amino-α-hydroxybutyryl side chain at the C-1 amino group of the deoxystreptamine moiety of kanamycin A. … M. avium-intracellulare (MAC) is a type of nontuberculous mycobacteria (NTM) found in water and soil.
Synonyms: 1-N-(L(−)-γ-amino-α-hydroxybutyryl)kanamycin A, -D-GLUCOPYRANOSYL-(1->4)-O-(6-AMINO-6-DEOXY-.ALPHA.-D-GLUCOPYRANOSYL-(1->6))-N(SUP 3)-(4-AMINO-L-2-HYDROXYBUTYRYL)-2-DEOXY-L-STREPTAMINECategories: Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index, Antibacterials for Systemic UseCefprozil
go.drugbank.com/drugs/DB01150ApprovedInvestigationalCefprozil is a cephalosporin antibiotic that is commonly employed to treat a variety of bacterial infections, including those of the ear and skin, bronchitis, and others.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseProducts: Cefzil Powder for Oral Suspension-250 Mg/ 5 Ml, PREFIX 250 MG FILM TABLET, 10 ADETAmoxicillin
go.drugbank.com/drugs/DB01060ApprovedInvestigationalVet approvedAmoxicillin, or BRL-2333, is a penicillin G derivative first described in the literature in 1972. … [A190648] Amoxicillin was granted FDA approval on 18 January 1974.[L11644]
Synonyms: (2S,5R,6R)-6-{[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acidMixtures: Amoxicillin Clav/pot, Amoxicillin/clav PotCarbocisteine
go.drugbank.com/drugs/DB04339ApprovedInvestigational[A230993] Carbocisteine is currently not FDA or Health Canada approved, but is approved for use in Asia, Europe, and South America. … Individuals with COPD have a greater risk of pulmonary infection due to the growth and accumulation of viruses and bacteria in thick bronchial mucus.
Synonyms: L-carbocysteine, S-carboxymethyl-L-cysteineProducts: PAXJARABE PARA LA TOS 2% NIÑOS, PAX JARABE PARA LA TOS 5% ADULTOS.