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Displaying results 2891 - 2900 of 9670 in total
  1. Drug

    Phenacetin

    go.drugbank.com/drugs/DB03783
    ApprovedWithdrawn

    Phenacetin was withdrawn from the Canadian market in June 1973 due to concerns regarding nephropathy (damage to or disease of the kidney).

  2. Drug

    FX06

    go.drugbank.com/drugs/DB05685
    Investigational

    It prevents leukocyte migration through the gap junctions of endothelial cells. FX06 has proven safe in acute and subchronic toxicological studies and recently entered clinical development. … It is being developed by Fibrex Medical Inc.

  3. Drug

    Ketobemidone

    go.drugbank.com/drugs/DB06738
    Investigational

    It also has some NMDA-antagonist properties. This makes it useful for some types of pain that don't respond well to other opioids.

  4. Drug

    Conestat alfa

    go.drugbank.com/drugs/DB09228
    Approved

    It does this through inhibition of several target proteases within these pathways including activated C1s, kallikrein, factor XIIa and factor XIa. … C1 esterase inhibitor has also been shown to inhibit the action of thrombin within the coagulation pathway, and tPA and plasmin within the fibrinolytic pathway.

  5. Drug

    Bevantolol

    go.drugbank.com/drugs/DB01295
    Investigational

    Bevantolol is a beta-1 adrenoceptor antagonist that has been shown to be as effective as other beta blockers for the treatment of angina pectoris and hypertension. … Mechanism of Action Animal experiments confirm both agonist and antagonist effects on alpha-receptors, in addition to antagonist activity at beta-1 receptors.

  6. Drug

    Artemisia vulgaris root

    go.drugbank.com/drugs/DB14170
    Approved

    Artemisia vulgaris root allergenic extract is used in allergenic testing.

    Mixtures: Slumber Soothe Detox Foot Pads
  7. Drug

    Antipyrine

    go.drugbank.com/drugs/DB01435
    Approved

    (From Martindale, The Extra Pharmacopoeia, 30th ed, p29) … An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver.

  8. Drug

    Lovotibeglogene autotemcel

    go.drugbank.com/drugs/DB18680
    ApprovedInvestigational

    [L49266] It was approved alongside [exagamglogene autotemcel] (Casgevy), another gene therapy, with the two treatments comprising the first cell-based gene therapies for the treatment of SCD in patients … lovotibeglogene autotemcel provides a functional copy of a modified beta-globin gene (β<sup>A-T87Q</sup>-globin) that when combined with α-globin, produces hemoglobins with similar oxygen-binding capacity as

  9. Drug

    Tripelennamine

    go.drugbank.com/drugs/DB00792
    ApprovedVet approved

    It is used to treat asthma; HAY fever; urticaria; and rhinitis; and also in veterinary applications. Tripelennamine is administered by various routes, including topically.

    Categories: Antihistamines, Anesthetics, Etc.Products: Pyribenzamine Tab 50mg
  10. Drug

    Eteplirsen

    go.drugbank.com/drugs/DB06014
    ApprovedInvestigational

    Eteplirsen was the first treatment for DMD approved by the FDA.[A244925] … It consists of a six-membered morpholino ring replacing the five-membered ribofuranosyl rings found in natural DNA and RNA.