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Octyl triazone

Trilostane

Trilostane is an inhibitor of 3 beta-hydroxysteroid dehydrogenase used in the treatment of Cushing's syndrome. It was withdrawn from the United States market in April 1994.

7MW3711

Developed by Mabwell, 7MW3711 is an antibody-drug conjugate targeting B7-H3.[L50918,L50923]

Metrizamide

Metrizamide is a solute for density gradient centrifugation offering higher maximum solution density without the problems of increased viscosity. It is also used as a resorbable, non-ionic contrast medium.

Sipagladenant

KW-6356 is a selective antagonist of adenosine A2A receptors developed by Kyowa Kirin.[L43822]

5-fluorotryptophan

5-fluorotryptophan can be used as substrate analogue to study enzyme mechanisms by NMR spectroscopy.

Cat dander extract

An allergic reaction to cats is induced by the presence of antigen-specific IgE antibodies that are bound to specific receptors on mast cells and basophils.

Lecanemab

[A253962,L44547] On January 6, 2023, lecanemab was granted accelerated approval by the FDA for the treatment of Alzheimer’s Disease.[L44547] It was granted full FDA approval on July 6, 2023.

Dornase alfa

In individuals with cystic fibrosis, extracellular DNA, which is an extremely viscous anion, is released by degenerating leukocytes that accumulate during inflammatory responses to infections.

Reteplase

Retavase is a deletion mutein of human tPA formed by deleting various amino acids present in endogenous human tPA.