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Displaying results 2951 - 2960 of 10000 in total
  1. Drug

    ABT-341

    go.drugbank.com/drugs/DB08044
    Experimental

    ABT-341 is a potent and selective DPP-4 inhibitor with a structure very similar to sitagliptin (in 2D; the 3D structure is significantly different). [A39406]

    Categories: Heterocyclic Compounds, 1-RingSynonyms: (1S,6R)-3-{[3-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRAZIN-7(8H)-YL]CARBONYL}-6-(2,4,5-TRIFLUOROPHENYL)CYCLOHEX-3-EN-1-AMINE
  2. Drug

    TAS-106

    go.drugbank.com/drugs/DB06656
    Investigational

    TAS-106 is a new nucleoside antimetabolite. TAS-106 has demonstrated strong antitumor activity without serious toxicity in nude rat models bearing human tumours [A31693].

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 4-Amino-1-((2R,3R,4R,5R)-4-ethynyl-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl)pyrimidin-2-one, 3'-C-Ethynylcytidine
  3. Drug

    1-(3-fluoro-4-(7-(5-methyl-1H-imidazol-2-yl)-1-oxo-2,3-dihydro-1H-isoindo-1-4-yl)-phenyl)-3-(3-trifluoromethyl-phenyl)-urea

    go.drugbank.com/drugs/DB18632
    Experimental

    Synonyms: 1-(3-fluoro-4-(7-(5-methyl-1H-imidazol-2-yl)-1-oxo-2,3-dihydro-1H-isoindo-1-4-yl)-phenyl)-3-(3-trifluoromethyl-phenyl)-urea, Urea, n-(4-(2,3-dihydro-7-(5-methyl-1h-imidazol-2-yl)-1-oxo-1h-isoindol-4-yl)-3-fluorophenyl)-n'-(3-(trifluoromethyl)phenyl)
  4. Drug

    Tesmilifene

    go.drugbank.com/drugs/DB04905
    Investigational

    Tesmilifene is a novel potentiator of chemotherapy which, when added to doxorubicin, achieved an unexpected and very large survival advantage over doxorubicin alone in a randomized trial in advanced breast

    Categories: P-glycoprotein inducers, P-glycoprotein inhibitorsSynonyms: N,N-diethyl-2-((4-phenylmethyl)phenoxy)ethanamine
  5. Drug

    Farudodstat

    go.drugbank.com/drugs/DB16049
    Investigational

    Farudodstat (ASLAN003) is under investigation in clinical trial NCT03451084 (A Dose Optimisation Study of ASLAN003 in Acute Myeloid Leukemia).

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 2-((3,5-difluoro-3'-methoxy-1,1'-biphenyl-4-yl)amino)nicotinic acid, 2-(3,5-difluoro-3'-methoxybiphenyl-4-ylamino)nicotinic acid
  6. Drug

    Spermidine

    go.drugbank.com/drugs/DB03566
    Investigational

    Spermidine is a polyamine formed from putrescine. It is found in almost all tissues in association with nucleic acids. … It is found as a cation at all pH values, and is thought to help stabilize some membranes and nucleic acid structures. It is a precursor of spermine.

    Synonyms: 4-azaoctane-1,8-diamine, 4-azaoctamethylenediamine
  7. Drug

    Osbond acid

    go.drugbank.com/drugs/DB14088
    Investigational

    Synonyms: Docosapentaenoic acid (22n-6), (All-Z)-4,7,10,13,16-docosapentaenoic acid
  8. Drug

    Tenofovir amibufenamide

    go.drugbank.com/drugs/DB18805
    Investigational

    Synonyms: Alanine, n-((s)-(((1r)-2-(6-amino-9h-purin-9-yl)-1-methylethoxy)methyl)phenoxyphosphinyl)-2-methyl-, 1-methylethyl ester
  9. Drug

    JS-K

    go.drugbank.com/drugs/DB17257
    Experimental

    Synonyms: 1-piperazinecarboxylic acid, 4-(2-(2,4-dinitrophenoxy)-1-oxidodiazenyl)-, ethyl ester, O2-(2,4-dinitrophenyl) 1-((4-ethoxycarbonyl)piperazin-1-yl)diazen-1-ium-1,2-diolate
  10. Drug

    Domatinostat

    go.drugbank.com/drugs/DB17521
    Investigational

    Synonyms: (e)-n-(2-aminophenyl)-3-(1-((4-(1-methyl-1h-pyrazol-4-yl)phenyl)sulfonyl)-1h-pyrrol-3-yl)acrylamide, 2-propenamide, n-(2-aminophenyl)-3-(1-((4-(1-methyl-1h-pyrazol-4-yl)phenyl)sulfonyl)-1h-pyrrol-3-yl)-, (2e)-