Search
Cenobamate
go.drugbank.com/drugs/DB06119ApprovedInvestigational[A188442,L10653] The exact mechanism of action has not been described in the literature, though it positively modulates GABA<sub>A</sub> and inhibits voltage gated sodium channels.
Categories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 SubstratesProducts: XCOPRI TITRATION PACK 50 mg, 100 mg, XCOPRI TITRATION PACK 12.5 mg, 25 mgAtazanavir
go.drugbank.com/drugs/DB01072ApprovedInvestigationalLike other protease inhibitors, it is used only in combination with other HIV medications. The U.S. Food and Drug Administration (FDA) approved atazanavir on June 20, 2003. … Like other antiretrovirals, it is used to treat infection of human immunodeficiency virus (HIV).
Mixtures: ANCEF ® R, ANCEF ® RCategories: Heterocyclic Compounds, 1-Ring, P-glycoprotein inducersMagnesium oxide
go.drugbank.com/drugs/DB01377ApprovedInvestigationalIt is used as an antacid and mild laxative and has many nonmedicinal uses.
Mixtures: PICOPREP 10 MG / 3,5 G /12 G ORAL ÇÖZELTI IÇIN TOZ, 2 SAŞE, DIMAG 365 MG TEK KULLANIMLIK TOZ ICEREN SAŞE, 10 ADETProducts: MAGNEZI KALSINE 100 G TOZ, 100 G, Magnesium 250 mgIcatibant
go.drugbank.com/drugs/DB06196ApprovedInvestigationalIcatibant is a synthetic decapeptide with 5 nonproteinogenic amino acid antagonist targeting the B<sub>2</sub> receptors with a similar affinity to bradykinin. … [L49776,L49781] The FDA approval was based on positive results obtained from 3 double-blind, randomized, controlled clinical trials known as FAST 1, 2, and 3, where a median time to almost complete symptom
Products: ICATIBANT EG, İKTU 30 MG/3 ML ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADETTelmisartan
go.drugbank.com/drugs/DB00966ApprovedInvestigationalGenerally, angiotensin II receptor blockers (ARBs) such as telmisartan bind to the angiotensin II type 1 (AT1) receptors with high affinity, causing inhibition of the action of angiotensin II on vascular … smooth muscle, ultimately leading to a reduction in arterial blood pressure.
Synonyms: 4'-((4-methyl-6-(1-methyl-2-benzimidazolyl)-2-propyl-1-benzimidazolyl)methyl)-2-biphenylcarboxylic acid, 4'-((1,4'-dimethyl-2'-propyl(2,6'-bi-1H-benzimidazol)-1'-yl)methyl)-(1,1'-biphenyl)-2-carboxylic acidMixtures: XIFEN A®80 /10 MG, XIFEN A ®80 /5 MGAbemaciclib
go.drugbank.com/drugs/DB12001ApprovedInvestigationalAbemaciclib is an antitumor agent and dual inhibitor of cyclin-dependent kinases 4 (CDK4) and 6 (CDK6) that are involved in the cell cycle and promotion of cancer cell growth in case of unregulated activity … It is either given alone in patients who has undergone endocrine therapy and chemotherapy after the metastasis of cancer, or in combination with [DB00947].
Categories: MATE 1 Inhibitors, MATE 1 SubstratesProducts: VERZENIO 50 MG, VERZENIO® 100 MGFosaprepitant
go.drugbank.com/drugs/DB06717ApprovedInvestigationalIt is a prodrug of Aprepitant. It aids in the prevention of acute and delayed nausea and vomiting associated with chemotherapy treatment.
Categories: Neurokinin 1 Antagonists, Heterocyclic Compounds, 1-RingProducts: FOSAPRANT 150 MG İ.V. İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ, 1 ADET, APRITANT IV® 150 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLEPropafenone
go.drugbank.com/drugs/DB01182ApprovedInvestigationalIt also has weak beta-blocking activity. The drug is generally well tolerated.
Synonyms: 1-(2-(2-hydroxy-3-(propylamino)propoxy)phenyl)-3-phenyl-1-propanone, 2-(2'-hydroxy-3'-propylaminopropoxy)-ω-phenylpropiophenoneCategories: Antiarrhythmics, Class I, P-glycoprotein inhibitorsPenciclovir
go.drugbank.com/drugs/DB00299ApprovedDisplaying low toxicity and good selectivity, penciclovir is a nucleoside analogue. … Penciclovir is a synthetic acyclic guanine derivative with antiviral activity used for the treatment of various herpes simplex virus (HSV) infections.
Synonyms: 9-(4-hydroxy-3-hydroxymethylbut-1-yl)-guanine, 9-[4-hydroxy-3-(hydroxymethyl)but-1-yl]guanineCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-RingRilpivirine
go.drugbank.com/drugs/DB08864ApprovedInvestigationalRilpivirine is non-nucleoside reverse transcriptase inhibitor (NNRTI) which is used for the treatment of HIV-1 infections in treatment-naive patients.[A31328] It is a diarylpyrimidine derivative. … [A31329] The internal conformational flexibility of rilpivirine and the plasticity of it interacting binding site gives it a very high potency and reduces the chance of resistance compared to other NNRTI's
Synonyms: 4-{[4-({4-[(E)-2-cyanovinyl]-2,6-dimethylphenyl}amino)pyrimidin-2-yl]amino}benzonitrileMixtures: ODEFSEY 200 MG/25 MG/25 MG FİLM KAPLI TABLET, 90 ADET, ODEFSEY 200 MG/25 MG/25 MG FİLM KAPLI TABLET, 30 ADET