Magnesium oxide

Identification

Name
Magnesium oxide
Accession Number
DB01377
Description

Magnesium oxide is an inorganic compound that occurs in nature as the mineral periclase. In aqueous media combines quickly with water to form magnesium hydroxide. It is used as an antacid and mild laxative and has many nonmedicinal uses.

Type
Small Molecule
Groups
Approved
Structure
Thumb
Weight
Average: 40.304
Monoisotopic: 39.97995652
Chemical Formula
MgO
Synonyms
  • Magnesia
External IDs
  • E-530
  • INS NO.530
  • INS-530

Pharmacology

Indication

Indicated for over-the-counter use as a supplement for cardiovascular and neuromuscular health, and as an antacid for relief of acid indigestion and upset stomach.

Associated Conditions
Associated Therapies
Contraindications & Blackbox Warnings
Learn about our commercial Contraindications & Blackbox Warnings data.
Learn More
Pharmacodynamics
Not Available
Mechanism of action

The term "Milk of Magnesia" was first used to describe a white aqueous, mildly alkaline suspension of magnesium hydroxide formulated at about 8%w/v. Milk of magnesia is primarily used to alleviate constipation, but can also be used to relieve indigestion and heartburn. When taken internally by mouth as a laxative, the osmotic force of the magnesia suspension acts to draw fluids from the body and to retain those already within the lumen of the intestine, serving to distend the bowel, thus stimulating nerves within the colon wall, inducing peristalsis and resulting in evacuation of colonic contents. Magnesium supplements have also been shown to reduce platelet aggregation by inhibiting in the influx of calcium, a crucial component of platelet aggregation.

Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half-life
Not Available
Clearance
Not Available
Adverse Effects
Learn about our commercial Adverse Effects data.
Learn More
Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
DrugInteraction
AcetaminophenMagnesium oxide can cause a decrease in the absorption of Acetaminophen resulting in a reduced serum concentration and potentially a decrease in efficacy.
AcetazolamideThe risk or severity of adverse effects can be increased when Acetazolamide is combined with Magnesium oxide.
AcetophenazineMagnesium oxide can cause a decrease in the absorption of Acetophenazine resulting in a reduced serum concentration and potentially a decrease in efficacy.
AclidiniumThe therapeutic efficacy of Magnesium oxide can be decreased when used in combination with Aclidinium.
Alendronic acidThe serum concentration of Alendronic acid can be decreased when it is combined with Magnesium oxide.
AlfacalcidolThe serum concentration of Magnesium oxide can be increased when it is combined with Alfacalcidol.
AlfentanilThe therapeutic efficacy of Magnesium oxide can be decreased when used in combination with Alfentanil.
AlimemazineMagnesium oxide can cause a decrease in the absorption of Alimemazine resulting in a reduced serum concentration and potentially a decrease in efficacy.
AlloinThe risk or severity of adverse effects can be increased when Magnesium oxide is combined with Alloin.
AllopurinolThe therapeutic efficacy of Allopurinol can be decreased when used in combination with Magnesium oxide.
Additional Data Available
  • Extended Description
    Extended Description

    Extended description of the mechanism of action and particular properties of each drug interaction.

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  • Severity
    Severity

    A severity rating for each drug interaction, from minor to major.

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  • Evidence Level
    Evidence Level

    A rating for the strength of the evidence supporting each drug interaction.

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  • Action
    Action

    An effect category for each drug interaction. Know how this interaction affects the subject drug.

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Food Interactions
  • Take with food. When using magnesium to treat calcium oxalate nephrolithiasis, magnesium oxide should be taken with food.
  • Take with or without food. Many different products contain magnesium oxide; refer to the product monograph for more specific instruction. Taking magnesium supplements with food may reduce the risk of diarrhea.

Products

Active Moieties
NameKindUNIICASInChI Key
Magnesium cationionicT6V3LHY83822537-22-0JLVVSXFLKOJNIY-UHFFFAOYSA-N
MagnesiumunknownI38ZP9992A7439-95-4RSHAOIXHUHAZPM-UHFFFAOYSA-N
International/Other Brands
Magmitt
Over the Counter Products
NameDosageStrengthRouteLabellerMarketing StartMarketing EndRegionImage
Magnesium OxideTablet400 mg/1OralH. J. Harkins Company Inc.2017-06-16Not applicableUS flag
Magnesium OxideTablet400 mg/1OralQualitest2003-12-03Not applicableUS flag
Magnesium OxideTablet253 mg/1OralQualitest Pharmaceuticals2003-10-062018-10-01US flag
Magnesium OxideTablet400 mg/1Oralbryant ranch prepack2015-09-082017-12-31US flag
Magnesium OxideTablet420 mg/1OralRichmond Pharmaceuticals, Inc.2016-02-01Not applicableUS flag
Magnesium OxideTablet400 mg/1OralAphena Pharma Solutions - Tennessee, LLC2003-12-03Not applicableUS flag
Magnesium OxideTablet400 mg/1OralVirtus Pharmaceuticals2014-04-092016-10-04US flag
Magnesium OxideTablet400 mg/1OralSafecor Health, LLC2014-09-302019-11-11US flag
Magnesium OxideTablet400 mg/1OralState of Florida DOH Central Pharmacy2013-01-01Not applicableUS flag
Magnesium OxideTablet400 mg/1OralMethod Pharmaceuticals, LLC2018-07-25Not applicableUS flag
Additional Data Available
  • Application Number
    Application Number

    A unique ID assigned by the FDA when a product is submitted for approval by the labeller.

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  • Product Code
    Product Code

    A governmentally-recognized ID which uniquely identifies the product within its regulatory market.

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Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
Anaplex TabMagnesium oxide (50 mg) + Ascorbic acid (40 mg) + Calcium (160 mg) + Iodine (.05 mg) + Nicotinamide (30 mg) + Calcium pantothenate (15 mg) + Phosphorus (75.33 mg) + Potassium chloride (20 mg) + Pyridoxine hydrochloride (40 mg) + Vitamin A palmitate (2000 unit) + Vitamin D (133.33 unit)TabletOralAnabolic Laboratories Inc.1975-12-311996-10-02Canada flag
Aspirin Plus Stomach Guard Ext.stgth.capletMagnesium oxide (96.9 mg) + Acetylsalicylic acid (500 mg) + Calcium carbonate (246.2 mg) + Magnesium carbonate (52.3 mg)TabletOralSterling Winthrop Inc.1994-12-311996-09-10Canada flag
Aspirin Plus Stomach Guard Extra StrengthMagnesium oxide (96.95 mg) + Acetylsalicylic acid (500 mg) + Calcium carbonate (246.22 mg) + Magnesium carbonate (52.32 mg)TabletOralBayer Inc Consumer Care1995-12-311998-09-28Canada flag
Aspirin Plus Stomach Guard TabMagnesium oxide (63 mg) + Acetylsalicylic acid (325 mg) + Calcium carbonate (160 mg) + Magnesium carbonate (34 mg)TabletOralSterling Winthrop Inc.1994-12-311996-09-10Canada flag
Aspirin With Stomach GuardMagnesium oxide (63 mg) + Acetylsalicylic acid (325 mg) + Calcium carbonate (160 mg) + Magnesium carbonate (34 mg)TabletOralBayer Inc Consumer Care1997-10-012012-07-12Canada flag
Aspirin With Stomach Guard Extra Strength - TabMagnesium oxide (96.9 mg) + Acetylsalicylic acid (500 mg) + Calcium carbonate (246.2 mg) + Magnesium carbonate (52.3 mg)TabletOralBayer Inc Consumer Care1997-07-072012-07-12Canada flag
B6 Plus TabMagnesium oxide (50 mg) + Niacin (20 mg) + Potassium citrate (50 mg) + Pyridoxine hydrochloride (50 mg) + Riboflavin (2.4 mg) + Thiamine (10 mg)TabletOralVita Health Products Inc1979-12-312002-08-01Canada flag
C-apnto-B6 Vitamins W Magnesium TabMagnesium oxide (60 mg) + Ascorbic acid (240 mg) + Calcium pantothenate (500 mg) + Pyridoxine (250 mg)TabletOralMetagenics, Inc.1989-12-311996-10-02Canada flag
Calcemin AdvanceMagnesium oxide (40 mg/1) + Calcium carbonate (500 mg/1) + Previtamin D(3) (3 mg/1) + Sodium borate decahydrate (2.45 mg/1) + Zinc oxide (7.5 mg/1)Tablet, film coatedOralBayer Healthcare Llc.2016-04-01Not applicableUS flag
Calcemin SilverMagnesium oxide (40 mg/1) + Boron (2.6 mg/1) + Zinc oxide (7.5 mg/1)Tablet, film coatedOralBayer Healthcare Llc.2016-04-01Not applicableUS flag
Unapproved/Other Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
Active FEMagnesium oxide (30 mg/1) + Ascorbic acid (160 mg/1) + Beta carotene (2100 [iU]/1) + Cholecalciferol (400 [iU]/1) + Cupric oxide (1 mg/1) + Cyanocobalamin (30 ug/1) + DL-alpha tocopheryl acetate (40 [iU]/1) + Folic acid (1250 ug/1) + Iron (75 mg/1) + Nicotinamide (20 mg/1) + Pyridoxine hydrochloride (20 mg/1) + Riboflavin (4 mg/1) + Thiamine hydrochloride (4 mg/1) + Zinc oxide (20 mg/1)TabletOralGm Pharmaceuticals2013-11-11Not applicableUS flag
BacminMagnesium oxide (50 mg/1) + Ascorbic acid (500 mg/1) + Biotin (150 ug/1) + Chromium Cr-51 chloride (0.1 mg/1) + Cupric oxide (3 mg/1) + Cyanocobalamin (50 ug/1) + Ferrous fumarate (27 mg/1) + Flavone (50 mg/1) + Folic acid (1 mg/1) + Manganese gluconate (5 mg/1) + Nicotinamide (100 mg/1) + Calcium pantothenate (25 mg/1) + Pyridoxine hydrochloride (25 mg/1) + Riboflavin (20 mg/1) + Selenomethionine (50 ug/1) + Thiamine mononitrate (20 mg/1) + Vitamin A acetate (2000 [iU]/1) + Zinc oxide (22.5 mg/1) + alpha-Tocopherol acetate (30 [iU]/1)Tablet, coatedOralMarnel Pharmaceuticals, Llc2000-04-01Not applicableUS flag
Bal-Care DHAMagnesium oxide (25 mg/1) + Ascorbic acid (120 mg/1) + Beta carotene (2850 [iU]/1) + Calcium carbonate (219 mg/1) + Cholecalciferol (840 [iU]/1) + Cupric oxide (2 mg/1) + Cyanocobalamin (.012 mg/1) + DL-alpha tocopheryl acetate (3 mg/1) + Folic acid (1 mg/1) + Iodine (.223 mg/1) + Iron sucrose (1.35 mg/1) + Nicotinamide (20 mg/1) + Omega-3 fatty acids (430 mg/1) + Pyridoxine hydrochloride (50 mg/1) + Riboflavin (4 mg/1) + Sodium feredetate (25.65 mg/1) + Thiamine mononitrate (1.8 mg/1) + Zinc oxide (25 mg/1)KitOralPru Gen Pharmaceuticals2012-05-01Not applicableUS flag
Bal-Care DHA EssentialMagnesium oxide (25 mg/1) + Ascorbic acid (120 mg/1) + Beta carotene (2850 [iU]/1) + Calcium carbonate (219 mg/1) + Cholecalciferol (840 [iU]/1) + Cupric oxide (2 mg/1) + Cyanocobalamin (.012 mg/1) + DL-alpha tocopheryl acetate (3 mg/1) + Folic acid (1 mg/1) + Iodine (.223 mg/1) + Iron sucrose (1.35 mg/1) + Nicotinamide (20 mg/1) + Omega-3 fatty acids (374 mg/1) + Pyridoxine hydrochloride (50 mg/1) + Riboflavin (4 mg/1) + Sodium feredetate (25.65 mg/1) + Thiamine mononitrate (1.8 mg/1) + Zinc oxide (25 mg/1)KitOralPru Gen Pharmaceuticals2012-05-01Not applicableUS flag
BumP DHAMagnesium oxide (125 mg/1) + Cobamamide (500 mg/1) + Flavin adenine dinucleotide (1 mg/1) + Flavin mononucleotide (2 mg/1) + Iron (15 mg/1) + Leucovorin (1 mg/1) + Levomefolate magnesium (1 mg/1) + NADH (25 ug/1) + Omega-3 fatty acids (300 mg/1) + Potassium Iodide (250 ug/1) + Pyridoxal phosphate (5 mg/1) + Pyridoxine hydrochloride (20 mg/1) + Zinc glycinate (15 1/1)CapsuleOralCenturion Labs2017-03-242017-04-17US flag
Cavan AlphaMagnesium oxide (25 mg/1) + Ascorbic acid (120 mg/1) + Beta carotene (3000 [iU]/1) + Calcium carbonate (230 mg/1) + Cholecalciferol (800 [iU]/1) + Cupric oxide (2 mg/1) + Cyanocobalamin (12 ug/1) + DL-alpha tocopheryl acetate (3 mg/1) + Folic acid (1 mg/1) + Iodine (220 ug/1) + Iron (27 mg/1) + Nicotinamide (20 mg/1) + Omega-3 fatty acids (300 mg/1) + Pyridoxine hydrochloride (50 mg/1) + Riboflavin (4 mg/1) + Thiamine mononitrate (1.8 mg/1) + Zinc oxide (25 mg/1)KitOralSeton Pharmaceuticals2010-07-012013-09-30US flag
Cavan Folate DHAMagnesium oxide (25 mg/1) + Magnesium oxide (25 mg/1) + Ascorbic acid (70 mg/1) + Ascorbic acid (70 mg/1) + Beta carotene (2700 [iU]/1) + Beta carotene (2700 [iU]/1) + Calcium carbonate (100 mg/1) + Calcium carbonate (100 mg/1) + Cholecalciferol (400 [iU]/1) + Cholecalciferol (400 [iU]/1) + Cupric oxide (2 mg/1) + Cupric oxide (2 mg/1) + Cyanocobalamin (12 ug/1) + Cyanocobalamin (12 ug/1) + DL-alpha tocopheryl acetate (30 [iU]/1) + DL-alpha tocopheryl acetate (30 [iU]/1) + Doconexent (250 mg/1) + Doconexent (250 mg/1) + Ferrous fumarate (65 mg/1) + Ferrous fumarate (65 mg/1) + Folic acid (1 mg/1) + Folic acid (1 mg/1) + Nicotinamide (18 mg/1) + Nicotinamide (18 mg/1) + Pyridoxine hydrochloride (2.5 mg/1) + Pyridoxine hydrochloride (2.5 mg/1) + Riboflavin (1.8 mg/1) + Riboflavin (1.8 mg/1) + Thiamine mononitrate (1.6 mg/1) + Thiamine mononitrate (1.6 mg/1) + Zinc oxide (25 mg/1) + Zinc oxide (25 mg/1)KitOralSeton Pharmaceuticals2010-06-042012-03-31US flag
Cavan Folate DHAMagnesium oxide (25 mg/1) + Magnesium oxide (25 mg/1) + Ascorbic acid (70 mg/1) + Ascorbic acid (70 mg/1) + Beta carotene (2700 [iU]/1) + Beta carotene (2700 [iU]/1) + Calcium carbonate (100 mg/1) + Calcium carbonate (100 mg/1) + Cholecalciferol (400 [iU]/1) + Cholecalciferol (400 [iU]/1) + Cupric oxide (2 mg/1) + Cupric oxide (2 mg/1) + Cyanocobalamin (12 ug/1) + Cyanocobalamin (12 ug/1) + DL-alpha tocopheryl acetate (30 [iU]/1) + DL-alpha tocopheryl acetate (30 [iU]/1) + Doconexent (250 mg/1) + Doconexent (250 mg/1) + Ferrous fumarate (65 mg/1) + Ferrous fumarate (65 mg/1) + Folic acid (1 mg/1) + Folic acid (1 mg/1) + Nicotinamide (18 mg/1) + Nicotinamide (18 mg/1) + Pyridoxine hydrochloride (2.5 mg/1) + Pyridoxine hydrochloride (2.5 mg/1) + Riboflavin (1.8 mg/1) + Riboflavin (1.8 mg/1) + Thiamine mononitrate (1.6 mg/1) + Thiamine mononitrate (1.6 mg/1) + Zinc oxide (25 mg/1) + Zinc oxide (25 mg/1)KitOralSeton Pharmaceuticals2010-06-042012-03-31US flag
Cavan Folate OBMagnesium oxide (25 mg/1) + Ascorbic acid (70 mg/1) + Beta carotene (2700 [iU]/1) + Calcium carbonate (100 mg/1) + Cholecalciferol (400 [iU]/1) + Cupric oxide (2 mg/1) + Cyanocobalamin (12 ug/1) + DL-alpha tocopheryl acetate (30 [iU]/1) + Ferrous fumarate (65 mg/1) + Folic acid (1 mg/1) + Nicotinamide (18 mg/1) + Pyridoxine hydrochloride (2.5 mg/1) + Riboflavin (1.8 mg/1) + Thiamine mononitrate (1.6 mg/1) + Zinc oxide (25 mg/1)TabletOralSeton Pharmaceuticals2010-08-232012-05-31US flag
Cavan-EC SOD DHAMagnesium oxide (25 mg/1) + Ascorbic acid (130 mg/1) + Beta carotene (3000 [iU]/1) + Calcium carbonate (230 mg/1) + Cholecalciferol (410 [iU]/1) + Cyanocobalamin (12 ug/1) + DL-alpha tocopheryl acetate (30 mg/1) + Folic acid (1 mg/1) + Nicotinamide (20 mg/1) + Omega-3 fatty acids (440 mg/1) + Pyridoxine hydrochloride (28 mg/1) + Riboflavin (4 mg/1) + Sodium feredetate (30 mg/1) + Zinc oxide (26 mg/1)KitOralPhysicians Total Care, Inc.2010-08-242013-01-15US flag

Categories

ATC Codes
A02AA02 — Magnesium oxideA12CC10 — Magnesium oxideA06AD02 — Magnesium oxide
Drug Categories
Classification
Not classified

Chemical Identifiers

UNII
3A3U0GI71G
CAS number
1309-48-4
InChI Key
AXZKOIWUVFPNLO-UHFFFAOYSA-N
InChI
InChI=1S/Mg.O/q+2;-2
IUPAC Name
magnesium(2+) oxidandiide
SMILES
[O--].[Mg++]

References

Synthesis Reference

Jajnya D. Panda, Santosh K. Mahapatra, "Process for the production of magnesium oxide from brine or bittern." U.S. Patent US4370422, issued June, 1921.

US4370422
General References
  1. Kh R, Khullar M, Kashyap M, Pandhi P, Uppal R: Effect of oral magnesium supplementation on blood pressure, platelet aggregation and calcium handling in deoxycorticosterone acetate induced hypertension in rats. J Hypertens. 2000 Jul;18(7):919-26. [PubMed:10930190]
  2. Shechter M, Merz CN, Paul-Labrador M, Meisel SR, Rude RK, Molloy MD, Dwyer JH, Shah PK, Kaul S: Oral magnesium supplementation inhibits platelet-dependent thrombosis in patients with coronary artery disease. Am J Cardiol. 1999 Jul 15;84(2):152-6. [PubMed:10426331]
Human Metabolome Database
HMDB0015458
KEGG Drug
D01167
KEGG Compound
C12567
PubChem Compound
14792
PubChem Substance
46504815
ChemSpider
5254017
RxNav
6582
ChEBI
31794
ChEMBL
CHEMBL1200572
PharmGKB
PA450298
Drugs.com
Drugs.com Drug Page
Wikipedia
Magnesia
AHFS Codes
  • 88:29.00* — Minerals

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
4CompletedNot AvailableBowel preparation therapy1
4CompletedDiagnosticColonoscopy1
4CompletedDiagnosticHemodynamics / Hyponatremia1
4CompletedSupportive CareMalignant Neoplasm of Colon1
4CompletedTreatmentBMI >30 kg/m21
4CompletedTreatmentCathartic Colon1
4CompletedTreatmentColonoscopy1
4CompletedTreatmentFunctional Constipation1
4RecruitingDiagnosticBowel Preparation Solutions1
4RecruitingPreventionSurgery--Complications / Wounds and Injuries1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
  • Bayer Healthcare
  • Blaine Pharmaceuticals
  • Gallipot
  • Major Pharmaceuticals
  • Manne Co.
  • Mckesson Corp.
  • Particle Dynamics Co.
  • Qualitest
  • Rising Pharmaceuticals
  • Rugby Laboratories
  • Walgreen Co.
Dosage Forms
FormRouteStrength
TabletOral243 mg
TabletOral950 mg
Tablet, coatedOral1188 mg
Powder, for solutionOral0.01 g
PowderParenteral1 g/50g
KitOral
KitNot applicable
Tablet, film coated8000 IU
PowderOral670 mg
TabletOral
Tablet, coatedOral
GranuleOral670 mg/6.1g
Powder, for solutionOral670 mg
CapsuleOral250 mg
TabletOral253 mg/1
TabletOral400 mg/1
TabletOral420 mg/1
TabletOral
Powder1 kg/1kg
Powder, for solutionOral100 g
CapsuleOral150 mg
Granule, for solutionOral670 mg
CapsuleOral
TabletOral8.3 mg
Powder, for solutionOral
Powder, for solutionOral10 mg
Capsule, gelatin coatedOral
Powder, meteredOral
PillOral
LiquidOral
WaferOral
Granule700 mg
Granule50 gr
Powder, for solutionOral12 g
SolutionIrrigation
LiquidIrrigation
Tablet, chewableOral5000 IU
Tablet, film coatedOral
Tablet, chewableOral
Capsule, liquid filledOral
Prices
Unit descriptionCostUnit
Phillips 500 mg caplet0.18USD caplet
Magnesium oxide 400 mg tablet0.13USD tablet
Magnesium oxide 420 mg tablet0.11USD tablet
Magox 400 tablet0.11USD tablet
Mag-oxide 400 mg tablet0.09USD tablet
Magnesium oxide powder heavy0.05USD g
Magnesium oxide 500 mg tablet0.04USD tablet
Maox 420 mg tablet0.04USD tablet
Magnesium oxide 250 mg tablet0.03USD tablet
DrugBank does not sell nor buy drugs. Pricing information is supplied for informational purposes only.
Patents
Patent NumberPediatric ExtensionApprovedExpires (estimated)Region
US8450338No2013-05-282028-10-10US flag
US8481083No2013-07-092028-10-10US flag
US9827231No2017-11-282034-06-23US flag
US10624879No2014-06-232034-06-23US flag
Additional Data Available
  • Filed On
    Filed On

    The date on which a patent was filed with the relevant government.

    Learn more

Properties

State
Solid
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
logP-0.57ChemAxon
pKa (Strongest Acidic)3.09ChemAxon
Physiological Charge2ChemAxon
Hydrogen Acceptor Count0ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area0 Å2ChemAxon
Rotatable Bond Count0ChemAxon
Refractivity0 m3·mol-1ChemAxon
Polarizability1.78 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET Features
PropertyValueProbability
Human Intestinal Absorption+0.9838
Blood Brain Barrier+0.9837
Caco-2 permeable+0.6708
P-glycoprotein substrateNon-substrate0.8922
P-glycoprotein inhibitor INon-inhibitor0.9725
P-glycoprotein inhibitor IINon-inhibitor0.995
Renal organic cation transporterNon-inhibitor0.9248
CYP450 2C9 substrateNon-substrate0.8638
CYP450 2D6 substrateNon-substrate0.894
CYP450 3A4 substrateNon-substrate0.8026
CYP450 1A2 substrateNon-inhibitor0.8153
CYP450 2C9 inhibitorNon-inhibitor0.9268
CYP450 2D6 inhibitorNon-inhibitor0.9535
CYP450 2C19 inhibitorNon-inhibitor0.9338
CYP450 3A4 inhibitorNon-inhibitor0.9869
CYP450 inhibitory promiscuityLow CYP Inhibitory Promiscuity0.9062
Ames testNon AMES toxic0.7478
CarcinogenicityCarcinogens 0.7198
BiodegradationReady biodegradable0.7705
Rat acute toxicity2.2618 LD50, mol/kg Not applicable
hERG inhibition (predictor I)Weak inhibitor0.9031
hERG inhibition (predictor II)Non-inhibitor0.977
ADMET data is predicted using admetSAR, a free tool for evaluating chemical ADMET properties. (23092397)

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available

Drug created on July 06, 2007 14:30 / Updated on September 25, 2020 18:37

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