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Displaying results 2971 - 2980 of 4288 in total
  1. Drug

    Hyaluronidase

    go.drugbank.com/drugs/DB14740
    ApprovedInvestigational

    [A199026] Early research into hyaluronidase identified it as a "spreading factor" which allowed for increased permeability of the connective tissue.

  2. Drug

    Lumasiran

    go.drugbank.com/drugs/DB15935
    ApprovedInvestigational

    [L23394] Prior to this approval, therapy consisted of symptomatic treatment such as hyperhydration, inhibitors of crystallization, [pyridoxine], and renal transplant.

  3. Drug

    Thalidomide

    go.drugbank.com/drugs/DB01041
    ApprovedInvestigationalWithdrawn

    A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, thalidomide was withdrawn from the market due to teratogenic effects.

  4. Drug

    Dihydroergocornine

    go.drugbank.com/drugs/DB11273
    Approved

    [T190] It is found as one of the components in the ergoloid mesylate mixture. To know more about this mixture please refer to [DB01049]

  5. Drug

    Pyruvaldehyde

    go.drugbank.com/drugs/DB03587
    Experimental

    An organic compound used often as a reagent in organic synthesis, as a flavoring agent, and in tanning. … It has been demonstrated as an intermediate in the metabolism of acetone and its derivatives in isolated cell preparations, in various culture media, and in vivo in certain animals. [PubChem]

  6. Drug

    Fenretinide

    go.drugbank.com/drugs/DB05076
    Investigational

    A synthetic retinoid that is used orally as a chemopreventive against prostate cancer and in women at risk of developing contralateral breast cancer. It is also effective as an antineoplastic agent.

  7. Drug

    Zafirlukast

    go.drugbank.com/drugs/DB00549
    Approved

    It is available as a tablet and is usually dosed twice daily. Another leukotriene receptor antagonist is montelukast (Singulair), which is usually taken just once daily.

  8. Drug

    Dimercaprol

    go.drugbank.com/drugs/DB06782
    Approved

    It was developed as an experimental antidote against the arsenic-based poison gas Lewisite. It has been used clinically since 1949 in arsenic, cadmium and mercury poisoning.

  9. Drug

    Tegoprazan

    go.drugbank.com/drugs/DB16690
    Investigational

    Tegoprazan (also known as CJ-12420) is a novel therapeutic developed by CJ Healthcare Corp for treating acid-related gastrointestinal diseases.

  10. Drug

    Iopentol

    go.drugbank.com/drugs/DB13861
    Experimental

    Iopentol is used as a contrast medium.