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COVID-19 Nucleocapsid-GM-CSF Protein Lactated Ringer's Injection
go.drugbank.com/drugs/DB15845ExperimentalAs of July 2020, Medicine Invention Design, Inc. is sponsoring a small, controlled clinical trial for the COVID-19 AP TP Vaccine for ‘proof of concept.’ … The vaccine utilizes granulocyte macrophage-colony stimulating factor (GM-CSF), a cytokine known to enhance vaccine efficacy through prolongation of humoral and cell immunity.
Synonyms: COVID-19 Therapeutic Vaccine - Nucleocapsid-GM-CSF Protein Lactated Ringer's InjectionBHV-1300
go.drugbank.com/drugs/DB22673InvestigationalBHV-1300 is a IgG<sub>1,2,4</sub> selective degrader being investigated for the treatment of Grave's disease.
Paritaprevir
go.drugbank.com/drugs/DB09297ApprovedInvestigationalBy combining multiple antiretroviral medications into fixed dose products, the viral lifecycle can be targeted at multiple stages while simultaneously reducing the risk of developing resistant viral strains
Mixtures: VIEKIRAX 12.5 MG/75 MG/50 MG FILM KAPLI TABLET ,56 TABLETSynonyms: (2R,6S,12Z,13aR,14aR,16aS)-N-(cyclopropanesulfonyl)-6-[(5-methylpyrazine-2-carbonyl)amino]-5,16-dioxo-2-[(phenanthridin-6-yl)oxy]-1,2,3,6,7,8,9,10,11,13a,14,15,16,16a-tetradecahydrocyclopropa[e]pyrroloSalicylamide
go.drugbank.com/drugs/DB08797ApprovedIt has similar medicinal uses to aspirin. Salicylamide is used in combination with both aspirin and caffeine in the over-the-counter pain remedies
Mixtures: FONGTIT 600 CAPSULE, Be Flex PlusTocopherol
go.drugbank.com/drugs/DB11251ApprovedInvestigationalThey present strong antioxidant activities, and it is determined as the major form of vitamin E. … Tocopherols can be found in the diet as part of vegetable oil such as corn, soybean, sesame, and cottonseed.
Categories: Vitamin E, tocopherol (vit E)Products: VITAMINA E VCAMK-4541
go.drugbank.com/drugs/DB17016ExperimentalMK-4541 is a 4-azasteroid and a selective androgen receptor modulator (SARM). MK-4541 acts as a dual selective SARM and is both a potent androgen receptor antagonist and a 5α-reductase inhibitor.
Ebola Zaire vaccine (live, attenuated)
go.drugbank.com/drugs/DB15595ApprovedInvestigational[A189018] This vaccine was later sold to NewLink Genetics, a biotech company that held the license to the vaccine from 2010 to 2014, although the vaccine was not marketed. … Ervebo, the marketed Ebola virus vaccine by Merck, was first approved by the European Commission in November 2019 after the European Medicines Agency recommended it be licensed.
Synonyms: Ebola Zaire Vaccine (rVSV∆G-ZEBOV-GP, live), EBOLA ZAÏRE VACCINE (rVSV [DELTA] G-ZEBOV-GP, LIVE)Bimekizumab
go.drugbank.com/drugs/DB12917ApprovedInvestigationalBimekizumab is a humanized monoclonal antibody directed towards IL-17, which was approved for use in the EU on August 20, 2021, for the treatment of plaque psoriasis. … [L39665,L39680] It is the first IL-17 inhibitor to target both IL-17A and IL-17F.
Ubrogepant
go.drugbank.com/drugs/DB15328ApprovedInvestigational[A189207] Ubrogepant was approved by Health Canada on November 10, 2022. … [A189207,A189213] Previous agents within this class were efficacious but limited by liver toxicity - this led to the development of ubrogepant, which was designed to be a hepatoxicity-free alternative
Tebapivat
go.drugbank.com/drugs/DB19338InvestigationalTebapivat is under investigation in clinical trial NCT05490446 (A Study of Tebapivat (AG-946) in Participants With Anemia Due to Lower-risk Myelodysplastic Syndromes (LR-MDS)).