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Displaying results 2981 - 2990 of 10000 in total
  1. Drug

    Mecbotamab vedotin

    go.drugbank.com/drugs/DB17442
    Investigational

    Mecbotamab vedotin is an anti-Axl humanized monoclonal antibody conjugated to monomethyl auristatin E using a cleavable linker (CAB-Axl-ADC).[A255212]

    Synonyms: -CHAIN, DIMER, THIOETHER WITH N-(((4-((N-(6-(3-MERCAPTO-2,5-DIOXO, IMMUNOGLOBULIN G1 (DE-450-LYSINE), ANTI-(HUMAN TYROSINE KINASE RECEPTOR AXL) (HUMAN-MUS MUSCULUS MONOCLONAL BA301 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL BA301 .KAPPA.
  2. Drug

    TEL540-548

    go.drugbank.com/drugs/DB17461
    Investigational

    TEL540-548 is a recombinant peptide consisting of the amino acid residues 540 to 548 of the human telomerase reverse transcriptase (hTERT).

  3. Drug

    Disomotide

    go.drugbank.com/drugs/DB17469
    Investigational

    Disomotide is a synthetic peptide cancer vaccine.

    Synonyms: L-valine, l-isoleucyl-l-methionyl-l-.alpha.-aspartyl-l-glutaminyl-l-valyl-l-prolyl-l-phenylalanyl-l-seryl-
  4. Drug

    Red blood cell-encapsulated L-asparaginase

    go.drugbank.com/drugs/DB17477
    Investigational

    It is being investigated in cancers.[L44923] … Red blood cell-encapsulated L-asparaginase is [Asparaginase Escherichia coli] encapsulated inside donor-derived red blood cells, which target cancer cells capable of altering asparagine and glutamine metabolism

    Synonyms: RBC-encapsulated l-asparaginase, Erythrocyte encapsulated l-asparaginase
  5. Drug

    HPV-16 trojan peptide vaccine

    go.drugbank.com/drugs/DB17496
    Investigational

    CD4 and CD8 T cell responses. … HPV-16 trojan peptide vaccine is an investigational cancer immunotherapy consisting of a novel Trojan peptide complex, composed of human papilloma virus 16 (HPV 16) epitopes, to stimulate antigen-specific

  6. Drug

    Vidutolimod

    go.drugbank.com/drugs/DB17500
    Investigational

    Vidutolimod is a Toll-like receptor 9 (TLR9) agonist. It is an investigational cancer vaccine.

    Synonyms: Dna, d(g-g-g-g-g-g-g-g-g-g-g-a-c-g-a-t-c-g-t-c-g-g-g-g-g-g-g-g-g-g), Cmp-001 component cpg-a oligodeoxynucleotide tlr9 agonist
  7. Drug

    6-diazo-5-oxo-L-norleucine

    go.drugbank.com/drugs/DB17537
    Investigational

    6-diazo-5-oxo-L-norleucine is a broad-acting glutamine antagonist.

    Synonyms: 6-Diazo-5-oxo-L-norleucine
  8. Drug

    D2C7 immunotoxin

    go.drugbank.com/drugs/DB17540
    Investigational

    D2C7 immunotoxin (D2C7-IT) is an investigational dual-specific monoclonal antibody targeting EGFRwt and EGFRvIII with a genetically engineered form of the _Pseudomonas exotoxin_, PE38-KDEL. … D2C7-IT is under investigation in clinical trial NCT04160494 (D2C7-IT With Atezolizumab for Recurrent Gliomas).

  9. Drug

    PLX51107

    go.drugbank.com/drugs/DB17543
    Investigational

    PLX51107 is a potent and selective inhibitor of the bromodomain and extraterminal (BET) protein family. … [A257246,A257251] PLX51107 is under investigation in clinical trial NCT04022785 (PLX51107 and Azacitidine in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome).

    Synonyms: Benzoic acid, 4-(6-(3,5-dimethyl-4-isoxazolyl)-1-((1s)-1-(2-pyridinyl)ethyl)-1h-pyrrolo(3,2-b)pyridin-3-yl)-Categories: Heterocyclic Compounds, 1-Ring
  10. Drug

    Timdarpacept

    go.drugbank.com/drugs/DB17544
    Investigational

    IMM01 is a recombinant human signal regulatory protein α (SIRPα) IgG 1 fusion protein. … [A257261] IMM01 is under investigation in clinical trial NCT05140811 (A Study of IMM01 Combined With Azacitidine in Patients With Acute Myeloid Leukemia and Myelodysplastic Syndrome).