6-diazo-5-oxo-L-norleucine

DB17537InvestigationalSmall molecule

6-diazo-5-oxo-L-norleucine is a broad-acting glutamine antagonist.

Chemical structure of 6-diazo-5-oxo-L-norleucine
Mechanism
Curator reviewed
Formula / weight
C6H9N3O3 · 171.156 g/mol (avg)
Code names
DON · NSC-7365

Resolves to

Compound
UNII03J0H273KZCAS157-03-9ChEMBLCHEMBL97485ChEBI183231
Structure
InChIKeyYCWQAMGASJSUIP-YFKPBYRVSA-NSMILESN[C@@H](CCC(=O)C=[N+]=[N-])C(O)=O
Targets
O94925GLSP17812CTPS1P19440GGT1Q06210GFPT1

What you can answer from here — as of September 05, 2026

4Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
1Clinical trialPhase, status and sponsor resolved per trial
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8+ReferencesStructured and connected to the statements they support
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Which drugs share a target with 6-diazo-5-oxo-L-norleucine, and which of those have an active Phase 3 trial?

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