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Displaying results 21 - 30 of 7452 in total
  1. Drug

    RP-72

    go.drugbank.com/drugs/DB17156
    Investigational

    Synonyms: 72 amino acid proprietary recombinant protein antagonist for the CXCR1 and CXCR2 receptors of interleukin-8
  2. Drug

    Onvitrelin ucalontide

    go.drugbank.com/drugs/DB19183
    Investigational

    Onvitrelin ucalontide is under investigation in clinical trial NCT01485848 (EP-100 Plus Paclitaxel Versus Paclitaxel Alone in Patients With Ovarian Cancer).

    Synonyms: -helical peptide for therapy of lhrh-expressing tumors)
  3. Drug

    IFx-Hu2.0

    go.drugbank.com/drugs/DB18396
    Investigational

    IFx-Hu2.0 is an investigational cancer vaccine. It is composed of plasmid DNA encoding the streptococcal membrane protein, Emm55, contained within a cationic polymer.

    Synonyms: Immunotherapeutic vaccine consisting of pAc/emm55, a plasmid DNA (pDNA), which codes for a modified immunogenic, streptococcal Emm55 protein, complexed with in vivo-jetPEI® polymer-based reagent linear
  4. Drug

    AVR-RD-05

    go.drugbank.com/drugs/DB18631
    Experimental

    It is under investigation for the treatment of Hunter Syndrome (Mucopolysaccharidosis Type II, MPSII).

    Synonyms: Ex vivo, lentiviral vector (LV)-mediated, genetically modified autologous cell therapy intended for the stable provision of functional human iduronate-2-sulfatase (IDS) enzyme to subjects with Hunter syndrome
  5. Drug

    Paclitaxel

    go.drugbank.com/drugs/DB01229
    ApprovedInvestigationalVet approved

    It is available as an intravenous solution for injection and the newer formulation contains albumin-bound paclitaxel marketed under the brand name Abraxane. … Used as a treatment for various cancers, paclitaxel is a mitotic inhibitor that was first isolated in 1971 from the bark of the Pacific yew tree which contains endophytic fungi that synthesize paclitaxel

    Synonyms: Paclitaxel protein-bound particles for injection suspensionProducts: Aclipak Concentrate for Solution for Infusion 6mg/ ml, FONKOPAC CONCENTRATE FOR SOLUTION FOR INFUSION 6MG/ML
  6. Drug

    AAV9/MFSD8

    go.drugbank.com/drugs/DB18616
    Experimental

    It was investigated for the treatment of neuronal ceroid lipofuscinosis type 7. … It is an adeno-associated virus serotype 9 (AAV9) vector with an engineered transgene encoding the human CLN7/MFSD8 gene for expression of active human major facilitator superfamily domain containing 8

    Synonyms: An adeno-associated virus serotype 9 (AAV9) vector with engineered transgene encoding the human CLN7/MFSD8 gene for expression of active human major facilitator superfamily domain containing 8
  7. Drug

    Tasadenoturev

    go.drugbank.com/drugs/DB17178
    Investigational

    Synonyms: adenovirus delta 24-RGD, an oncolytic adenovirus genetically modified for treatment of glioma
  8. Drug

    Iltamiocel

    go.drugbank.com/drugs/DB19059
    Investigational

    Synonyms: THE EXPANSION IS CONSISTENT WITH ROUTINE CELL CULTURE PRACTICES FOR ADHERENT CELLS. DURING ADHERENT CELL CULTURE EXPANSION, CELLS REP
  9. Drug

    Tividenofusp alfa

    go.drugbank.com/drugs/DB17628
    ApprovedInvestigational

    Tividenofusp alfa is a first-in-class, brain-penetrant enzyme replacement therapy (ERT) indicated for the treatment of Mucopolysaccharidosis type II (MPS II), also known as Hunter syndrome [L56097, L56099

    Synonyms: ENZYME TRANSPORT VEHICLE SPECIFIC FOR THE TRANSFERRIN RECEPTOR FUSED TO IDURONATE 2-SULFATASE
  10. Drug

    Izokibep

    go.drugbank.com/drugs/DB19081
    Investigational

    Izokibep is under investigation in clinical trial NCT05623345 (Psoriatic Arthritis Study of Izokibep).

    Synonyms: FUSION PROTEIN COMPOSED OF 3 BINDING DOMAINS CONSISTING OF THREE-ALPHA-HELIX MOTIFS, EACH DERIVED FROM THE IMMUNOGLOBULIN (IG)-BINDING Z-DOMAIN OF STAPHYLOCOCCAL PROTEIN A (SPA), ENGINEERED FOR BINDING