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Displaying results 21 - 30 of 10000 in total
  1. Drug

    Methoxy polyethylene glycol-epoetin beta

    go.drugbank.com/drugs/DB09107
    ApprovedInvestigational

    Methoxy polyethylene glycol-epoetin beta is a chemically synthesised Erythropoiesis Stimulating Agent (ESA) with a longer half-life than erythropoietin.

    Categories: Compounds used in a research, industrial, or household settingProducts: Mircera Solution for Injection 100mcg/0.3ml (Pre-filled Syringe), Mircera Solution for Injection 75mcg/0.3ml (Pre-filled Syringe)
  2. Drug

    Senna leaf

    go.drugbank.com/drugs/DB15889
    ApprovedInvestigational

    Synonyms: Cassia senna l.Mixtures: Senna S, Multilax 1 Cap
  3. Drug

    Galcanezumab

    go.drugbank.com/drugs/DB14042
    ApprovedInvestigational

    A pregnancy exposure registry has been established to evaluate the safety of this drug in pregnant women.[L42060] … Galcanezumab is a humanized monoclonal antibody developed by Eli Lilly and Company against human calcitonin gene-related peptide (CGRP).

    Products: EMGALITY SOLUTION FOR INJECTION IN PRE-FILLED PEN 120 MG/ML, Pontevia 120 mg solution for injection in pre-filled pen
  4. Drug

    Benralizumab

    go.drugbank.com/drugs/DB12023
    ApprovedInvestigational

    Benralizumab is a humanized recombinant monoclonal antibody of the isotype IgG1k immunoglobulin that specifically binds to the alpha chain of the interleukin 5 receptor (IL-5R) expressed on eosinophils … [A31294] It inhibits the binding of IL-5 as well as the hetero-oligomerization of the alpha and beta subunits of the IL-5R, thus blocking signal transduction.

    Categories: Interleukin-5 Receptor alpha-directed Cytolytic Antibody, Interleukin 5 Receptor alpha-directed Antibody InteractionsProducts: FASENRA®, Fasenra 30 mg solution for injection in pre-filled syringe
  5. Drug

    Romosozumab

    go.drugbank.com/drugs/DB11866
    ApprovedInvestigational

    In a comparison study of post menopausal women with osteoporosis and a past fracture, romosozumab for 12 months followed by alendronic acid for 12 months was superior to alendronic acid alone for 24 months … Romosozumab is a humanized monoclonal antibody indicated for the treatment of osteoperosis in postmenopausal women at high risk of fracture and patients who have failed in other treatments or are intolerant

    Products: EVENITY SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 105 MG/1.17 ML, EVENITY SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 105MG/1.17ML
  6. Drug

    Erenumab

    go.drugbank.com/drugs/DB14039
    ApprovedInvestigational

    Erenumab (AMG-334) (INN; trade name Aimovig) is a human monoclonal antibody designed specifically to bind and antagonize the calcitonin gene-related peptide receptor (CGRPR) as a means to prevent migraines … CGRP receptor, which is believed to play a critical role in migraine [L2823].

    Products: AIMOVIG SOLUTION FOR INJECTION IN PRE-FILLED PEN 70MG/ML, AIMOVIG SOLUTION FOR INJECTION IN PRE-FILLED PEN 140MG/ML
  7. Drug

    Semaglutide

    go.drugbank.com/drugs/DB13928
    ApprovedInvestigational

    Semaglutide is a glucagon-like peptide 1 (GLP-1) analog used to manage type 2 diabetes along with lifestyle changes, such as dietary restrictions and increased physical activity. … [L8678] The subcutaneous injection is administered once weekly and the tablet is administered once a day.

    Categories: Glucagon-like peptide-1 (GLP-1) analogues, GLP-1 AgonistsProducts: Wegovy® 1 mg/0.5 mL (1 mg/dose) Solution for injection in pre-filled pen, Ozempic® 1.34 mg/ml (1 mg/dose) Solution for injection in pre-filled pen
  8. Drug

    Mepolizumab

    go.drugbank.com/drugs/DB06612
    ApprovedInvestigational

    Eosinophils are involved in inflammatory immune responses, and prolonged hypereosinophilia (typically defined as absolute eosinophil levels of 1500/mm<sup>3</sup> or more) is associated with a spectrum … The pathogenesis of eosinophilia is complex, but IL-5 is recognized as a key cytokine involved in the differentiation, recruitment, activation, and prolonged survival of eosinophils in peripheral tissue

    Categories: Interleukin-5 AntagonistProducts: NUCALA SOLUTION FOR INJECTION IN PRE-FILLED PEN 100MG/ML, NUCALA SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 100MG/ML
  9. Drug

    Liraglutide

    go.drugbank.com/drugs/DB06655
    ApprovedInvestigational

    Victoza contains liraglutide, a synthetic analog of human glucagon-like peptide-1(GLP-1) and acts as a GLP-1 receptor agonist. … [A6932] Liraglutide is made by attaching a C-16 fatty acid (palmitic acid) with a glutamic acid spacer on the remaining lysine residue at position 26 of the peptide precursor.

    Mixtures: Xultophy Pre-filled Pen, XULTOPHY® SOLUCION PARA INYECCIÓNCategories: Glucagon-like peptide-1 (GLP-1) analogues, GLP-1 Agonists
  10. Drug

    Follitropin

    go.drugbank.com/drugs/DB00066
    ApprovedInvestigational

    However, a more recent study showed there is may be a slight clinical difference, with the alpha form tending towards a higher pregnancy rate and the beta form tending towards a lower pregnancy rate, but … The alpha subunit is glycosylated at Asn 51 and Asn 78 while the beta subunit is glycosylated at Asn 7 and Asn 24.

    Synonyms: FSH-a, FSH-bInternational brands: Cinnal-F