Search
Spironolactone
go.drugbank.com/drugs/DB00421ApprovedInvestigational[A178135, A261025] Spironolactone was developed in 1957, marketed in 1959, and approved by the FDA on January 21, 1960.[A178243] … [A178192] It promotes sodium and water excretion and potassium retention.
Mixtures: SPIRO COMP RATIO 50MG/20MG, SPIRO COMP RATIO 50MG/20MGCategories: Hormones, Hormone Substitutes, and Hormone AntagonistsAflibercept
go.drugbank.com/drugs/DB08885ApprovedInvestigational[A261130,L47915] Ziv-aflibercept, under the brand name Zaltrap, was developed as an intravenous injection for the treatment of metastatic colorectal cancer, and it was approved by the FDA and EMA in … [L47915] All five putative N-glycosylation sites on each polypeptide chain predicted by the primary sequence can be occupied with carbohydrates and exhibit some degree of chain heterogeneity, including
Categories: Enzymes and Coenzymes, Amino Acids, Peptides, and ProteinsProducts: EYLEA SOLUTION FOR INJECTION IN VIAL 2MG, EYLEA 40MG/ML SOLUTION FOR INJECTION IN VIALPaclitaxel
go.drugbank.com/drugs/DB01229ApprovedInvestigationalVet approvedIt is available as an intravenous solution for injection and the newer formulation contains albumin-bound paclitaxel marketed under the brand name Abraxane. … Used as a treatment for various cancers, paclitaxel is a mitotic inhibitor that was first isolated in 1971 from the bark of the Pacific yew tree which contains endophytic fungi that synthesize paclitaxel
Categories: paclitaxel and encequidar, Amino Acids, Peptides, and ProteinsSynonyms: 5beta,20-Epoxy-1,2-alpha,4,7beta,10beta,13alpha-hexahydroxytax-11-en-9-one 4,10-diacetate 2-benzoate 13-ester with (2R,3S)-N-benzoyl-3-phenylisoserineEphedra sinica root
go.drugbank.com/drugs/DB01363ApprovedNutraceuticalEphedra is an alkaloid chemical compound traditionally obtained from the plant _Ephedra sinica_. … The sale of ephedra-containing supplements intended to increase muscle weight or promote weight loss was banned in the United States in 2004 due to the risk for adverse effects and a lack of evidence for
Mixtures: Herbal Cold and Flu Formula - TabCategories: Herbs and Natural Products, Alpha-and Beta-adrenergic AgonistsOxycodone
go.drugbank.com/drugs/DB00497ApprovedIllicitInvestigationalfor an extended period. … [A178696] It is currently indicated as an immediate release product for moderate to severe pain and as an extended release product for chronic moderate to severe pain requiring continuous opioid analgesics
Mixtures: TARGIN 10MG/5MG, TARGIN 10MG/5MGCategories: oxycodone and naloxone, oxycodone and ibuprofenTriamcinolone
go.drugbank.com/drugs/DB00620ApprovedInvestigationalVet approved[L8249] Triamcinolone is more commonly seen in the forms triamcinolone hexacetonide, triamcinolone acetonide, and triamcinolone diacetate. … [L8255] Triamcinolone can be used as a one time adjunct treatment of osteoarthritic knee pain,[L8264] or first line as a topical treatment of corticosteroid responsive dermatoses.
Mixtures: ReadySharp-K, Physician EZ Use Joint Tunnel and Trigger Kit IICategories: Corticosteroids, Moderately Potent (Group II), Alimentary Tract and MetabolismCeftazidime
go.drugbank.com/drugs/DB00438ApprovedInvestigational[L32935] Ceftazidime was approved by the FDA on July 19, 1985, and is currently available either alone or in combination with the non-β-lactam β-lactamase inhibitor [avibactam] to treat a variety of … [A232920] β-lactam antibiotics, including cephalosporins, are PBP inhibitors that, through inhibition of essential PBPs, result in impaired cell wall homeostasis, loss of cell integrity, and ultimately
Synonyms: CAZProducts: Fortaz Inj 500mg/vial, Tazidime Inj 500mg/vialLinagliptin
go.drugbank.com/drugs/DB08882ApprovedInvestigationalLinagliptin differs from other DPP-4 inhibitors in that it has a non-linear pharmacokinetic profile, is not primarily eliminated by the renal system, and obeys concentration dependant protein binding[A37050 … Linagliptin is a DPP-4 inhibitor developed by Boehringer Ingelheim for the treatment of type II diabetes [L9557].
Synonyms: (R)-8-(3-aminopiperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(4-methylquinazolin-2-ylmethyl)-3,7-dihydro-purine-2,6-dioneMixtures: Glyxambi Film-Coated Tablets 10mg/5mg, TRAJENTA DUO FILM-COATED TABLETS 2.5MG / 500MGAzathioprine
go.drugbank.com/drugs/DB00993ApprovedInvestigationalAzathioprine is a prodrug of 6-mercaptopurine, first synthesized in 1956 by Gertrude Elion, William Lange, and George Hitchings in an attempt to produce a derivative of 6-mercaptopurine with a better therapeutic … [A189678,A189687,A189690] Azathioprine is used to treat inflammatory conditions like rheumatoid arthritis and as an immunosuppressant in the prevention of renal transplant rejection.
Categories: Antineoplastic and Immunomodulating Agents, Nucleic Acids, Nucleotides, and NucleosidesProducts: Imuran Inj 100mg, AZATHIOPRIN DURA N 25MGRamipril
go.drugbank.com/drugs/DB00178ApprovedInvestigationalRamipril may be used in the treatment of hypertension, congestive heart failure, nephropathy, and to reduce the rate of death, myocardial infarction and stroke in individuals at high risk of cardiovascular … Ramipril is a prodrug belonging to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is metabolized to ramiprilat in the liver and, to a lesser extent, kidneys.
Mixtures: RAMIPRIL COMP HEU 5/25MG N, TRINOMIA HARD CAPSULES 100mg/ 20mg/ 10mgCategories: Agents Acting on the Renin-Angiotensin System, ACE Inhibitors and Diuretics