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Oral Malodor (Halitosis)
go.drugbank.com/conditions/DBCOND0035973Drugs: DequaliniumSynonyms: Bad Breath, Bad breath - halitosisL-arginine
go.drugbank.com/drugs/DB17289ApprovedInvestigationalNutraceuticalMixtures: Aminosyn II 7% M In 10% Dextrose(dual Chamber), Aminosyn II 8.5% M In 20% Dextrose (dual Chamber)Davanat
go.drugbank.com/drugs/DB15311InvestigationalDavanat is under investigation in clinical trial NCT00054977 (Safety of GM-CT-01 With and Without 5-Fluorouracil in Patients With Solid Tumors).
Dicirenone
go.drugbank.com/drugs/DB20938ExperimentalThe usage of the INN stem '-renone' in the name indicates that Dicirenone is a mineralocorticoid receptor (MR, MCR, aldosterone receptor) antagonist. … Dicirenone has a monoisotopic molecular weight of 428.26 Da.
Elismetrep
go.drugbank.com/drugs/DB15287InvestigationalElismetrep is under investigation in clinical trial NCT02429102 (A Study to Investigate the Safety, Tolerability and Pharmacokinetics of MT-8554 in Healthy Subjects).
Patritumab deruxtecan
go.drugbank.com/drugs/DB21996InvestigationalPatritumab deruxtecan is under investigation in clinical trial NCT06596694 (Study of Patritumab Deruxtecan in Participants With Gastrointestinal Cancers (MK-1022-011) (HERTHENA-PanTumor02)).
Tocopherol
go.drugbank.com/drugs/DB11251ApprovedInvestigationalWhen the carbons at position 5- and 7- are not methylated, they can function as electrophilic centers that can trap reactive oxygen and nitrogen species. … The different types of tocopherol can be presented trimethylated, dimethylated or methylated in the positions 5-, 7- and 8-.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesVoxelotor
go.drugbank.com/drugs/DB14975Approvedto 20 million others worldwide. … [L10403] It was developed by Global Blood Therapeutics, Inc.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 SubstratesDarolutamide
go.drugbank.com/drugs/DB12941ApprovedInvestigational[A189054,A189063] Darolutamide was developed by Bayer HealthCare Pharmaceuticals Inc. and approved by the FDA on July 30th, 2019.[L10887] … [A189063] Though prior treatment for prostate cancer has been successful for these patients, the cancer eventually progresses to become resistant to existing therapies.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesMRK-003
go.drugbank.com/drugs/DB17015ExperimentalIt is the preclinical analog of [MK-0752], a drug in clinical development.[A252682]
Synonyms: (1'R,4R)-2-(2,2,2-trifluoroethyl)-5'-[(E)-3-[4-(trifluoromethyl)piperidin-1-yl]prop-1-enyl]spiro[1,2,5-thiadiazolidine-4,13'-tricyclo[8.2.1.03,8]trideca-3(8),4,6-triene] 1,1-dioxide