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Pitavastatin
go.drugbank.com/drugs/DB08860ApprovedInvestigational[A181084] Elevated cholesterol levels, and in particular, elevated low-density lipoprotein (LDL) levels, are an important risk factor for the development of CVD. … [A181090,A181093,A181096,A181427,A181475,A181538] Statins are considered a cost-effective treatment option for CVD due to their evidence of reducing all-cause mortality including fatal and non-fatal CVD
Categories: Cytochrome P-450 Substrates, P-glycoprotein substratesRepotrectinib
go.drugbank.com/drugs/DB16826ApprovedInvestigationalRepotrectinib is a next-generation tyrosine kinase inhibitor (TKI) specifically designed to address resistance in the treatment of non-small cell lung cancer (NSCLC), specifically due to mutations in the
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesDegarelix
go.drugbank.com/drugs/DB06699ApprovedInvestigationalChemically, it is a synthetic linear decapeptide amide with seven unnatural amino acids, five of which are D-amino acids. FDA approved on December 24, 2008.
Caprylic acid
go.drugbank.com/drugs/DB04519ApprovedInvestigationalWithdrawnIt is an oily liquid with a slightly unpleasant rancid-like smell that is minimally soluble in water. … Caprylic acid is an eight-carbon chain fatty acid, also known systematically as octanoic acid. It is found naturally in coconuts and breast milk.
Quercus acutissima whole
go.drugbank.com/drugs/DB14373InvestigationalIt is not an approved drug.
Mixtures: Dr. Forest Hand Sanitizer, Dr. Forest Hand SanitizerGenistein
go.drugbank.com/drugs/DB01645InvestigationalAn isoflavonoid derived from soy products. It inhibits protein-tyrosine kinase and topoisomerase-II (DNA topoisomerases, type II) activity and is used as an antineoplastic and antitumor agent. … It has been investigated in clinical trials as an alternative to classical hormone therapy to help prevent cardiovascular disease in postmenopausal women [A14417].
Mixtures: OSMEGA 600 MG/400 IU/25 MG EFERVESAN TABLET, 30 ADET, CALCIDAY G 1200 MG/800 IU/50 MG EFERVESAN TABLET, 45 ADETCategories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesGlutathione
go.drugbank.com/drugs/DB00143ApprovedInvestigationalNutraceuticalA tripeptide with many roles in cells. It conjugates to drugs to make them more soluble for excretion, is a cofactor for some enzymes, is involved in protein disulfide bond rearrangement and reduces peroxides.
Faricimab
go.drugbank.com/drugs/DB15303ApprovedInvestigational[L43085] On April 9, 2026, the FDA approved an updated label that extended faricimab treatment for macular edema following retinal vein occlusion (RVO) beyond six months.[L40026] … [A225985, A225990, A225995] Faricimab is an IgG<sub>1</sub>-derived bispecific antibody capable of simultaneously binding to and depleting VEGF-A and Ang-2, which has been developed to improve therapeutic
Citrus bioflavonoids
go.drugbank.com/drugs/DB14586ApprovedMixtures: Rose Hips 500plus Nu Life, Bioflavonoids With Rose Hips C Nu Life