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Ilantimod
go.drugbank.com/drugs/DB21742ExperimentalIlantimod is a small molecule drug. The usage of the INN stem '-imod' in the name indicates that Ilantimod is a immunomodulator, both stimulant/suppressive and stimulant.
Droxidopa
go.drugbank.com/drugs/DB06262ApprovedInvestigationalDroxidopa is a precursor of noradrenaline that is used in the treatment of Parkinsonism. It is approved for use in Japan and is currently in trials in the U.S. … Though L-DOPS has been used in Japan and Southeast Asia already for some time, it is also currently in clinical trials at the phase III point in the United States (U.S.), Canada, Australia, and throughout
Ixazomib
go.drugbank.com/drugs/DB09570ApprovedInvestigational[A7948] More than 99% of the drug compound is the R-enantiomer.[A264329] Ixazomib was approved by the FDA on November 20, 2015, making it the first oral proteasome inhibitor approved in the US. … Ixazomib is a reversible proteasome inhibitor. Because it is a modified peptide boronic acid with one chiral center,[A264329] it is considered a boronate proteasome inhibitor.
Albutrepenonacog alfa
go.drugbank.com/drugs/DB13884ApprovedIt is currently marketed in the forms of 250, 500, 1000 and 2000 IU/vial.[L2305] … Albutrepenonacog alfa (rIX-RFP) is a recombinant fusion protein that links a recombinant coagulation factor IX (rFIX) with a recombinant human albumin (rAlbumin).
Alirocumab
go.drugbank.com/drugs/DB09302ApprovedInvestigationalIt is a human monoclonal antibody part of the family of the PCSK9 inhibitors which are a novel class of anticholesterol therapeutics. From this family, it was the first agent to receive FDA approval. … Alirocumab is a biopharmaceutical that obtained FDA approval in July 2015 as a second line treatment for high cholesterol in adults whose LDL-cholesterol (LDL-C) is not controlled by the combination of
Isosorbide mononitrate
go.drugbank.com/drugs/DB01020ApprovedInvestigationalIsosorbide mononitrate is an organic nitrate with vasodilating properties. … [L11698, L11743] Isosorbide mononitrate is an active metabolite of [isosorbide dinitrate].
Synonyms: IS-5MN, IS 5-MNProducts: IS 5 MONO RATIO 20MG TAB, IS 5 MONO RATIO 40MG RETLisuride
go.drugbank.com/drugs/DB00589ApprovedIt may also act as an antagonist at dopamine D1 receptors, and as an agonist at some serotonin receptors (serotonin agonists). … An ergot derivative that acts as an agonist at dopamine D2 receptors (dopamine agonists).
Categories: Genito Urinary System and Sex HormonesSodium zirconium cyclosilicate
go.drugbank.com/drugs/DB14048ApprovedInvestigational[L2933] The treatment effect was maintained for up to 12 months.[L2933] … [L2933] It is administered orally and is odorless, tasteless, and stable at room temperature.
Gadoteric acid
go.drugbank.com/drugs/DB09132ApprovedInvestigationalGadoteric acid, commonly used in the salt form gadoterate meglumine, is a macrocyclic, ionic gadolinium-based contrast agent (GBCA). … [A263131] It is composed of the organic acid DOTA (1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid) used for its chelating properties, and gadolinium (Gd3+).
Anakinra
go.drugbank.com/drugs/DB00026ApprovedInvestigationalA few studies have evaluated the use of anakinra for the treatment of coronavirus disease 2019 (COVID-19). … [L35415] Anakinra is indicated for the management of rheumatoid arthritis (RA) in patients 18 years of age or older who have failed one or more disease-modifying antirheumatic drugs (DMARDs), as well as