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Moxonidine
go.drugbank.com/drugs/DB09242ApprovedInvestigationalWithdrawnMoxonidine is a new-generation centrally acting antihypertensive drug approved for the treatment of mild to moderate essential hypertension. It is suggested to be effective in cases where other agents such as thiazides, beta-blockers, AC...
Delavirdine
go.drugbank.com/drugs/DB00705ApprovedInvestigationalWithdrawnA potent, non-nucleoside reverse transcriptase inhibitor with activity specific for HIV-1.
Glutathione
go.drugbank.com/drugs/DB00143ApprovedInvestigationalNutraceuticalA tripeptide with many roles in cells. It conjugates to drugs to make them more soluble for excretion, is a cofactor for some enzymes, is involved in protein disulfide bond rearrangement and reduces peroxides.
Ixmyelocel-T
go.drugbank.com/drugs/DB17601InvestigationalDeveloped by Vericel Corporation, it is being investigated for cardiomyopathy.
Fluorofuranylnorprogesterone F-18
go.drugbank.com/drugs/DB15282InvestigationalFluorofuranylnorprogesterone F-18 is under investigation in clinical trial NCT02455453 (Assessment of Functional Status of Estrogen Receptors in Breast Cancer by Positron Emission Tomography).
CA-074 methyl ester
go.drugbank.com/drugs/DB07223ExperimentalIt is converted by cellular esterases to CA-074.[A258234,A258239]
Utidelone
go.drugbank.com/drugs/DB17575InvestigationalUtidelone (UTD1), a novel microtubule stabilizing agent, is an epothilone B analogue produced by genetic engineering.[A257544,A257549] It is under investigation in clinical trials for various cancers.
mRNA-3705
go.drugbank.com/drugs/DB17668InvestigationalDeveloped by Moderna TX Inc., it is being investigated for the treatment of methylmalonic academia.[A258843]
RLYB212
go.drugbank.com/drugs/DB17727InvestigationalIt is currently being developed by Rallybio for the prevention of fetal and neonatal alloimmune thrombocytopenia.