CA-074 methyl ester

DB07223ExperimentalSmall molecule

CA-074 methyl ester (CA-074Me) is a cell-permeable cathepsin B inhibitor. It is converted by cellular esterases to CA-074.

Chemical structure of CA-074 methyl ester
Formula / weight
C19H31N3O6 · 397.4659 g/mol (avg)
Also known as
CA 074 Me ester · CA 074 methyl ester · Methyl N-({(2s,3s)-3-[(propylamino)carbonyl]oxiran-2-Yl}carbonyl)-L-isoleucyl-L-prolinate
Code names
CA-074 Me

Resolves to

Compound
CAS147859-80-1ChEMBLCHEMBL262103PubChem6610318
Structure
InChIKeyXGWSRLSPWIEMLQ-YTFOTSKYSA-NSMILES[H][C@](C)(CC)[C@]([H])(NC(=O)[C@@]1([H])O[C@]1([H])C(=O)NCCC)C(=O)N1CCC[C@@]1([H])C(=O)OC
Targets
P07858CTSB

What you can answer from here — as of March 14, 2023

1Protein targetEach mapped to UniProt, with action and pharmacological action
Listed above
3+ReferencesStructured and connected to the statements they support
Sign in

Which drugs share a target with CA-074 methyl ester, and which of those have an active Phase 3 trial?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In