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Bronopol
go.drugbank.com/drugs/DB13960ApprovedThe agent is largely available commercially as an antibacterial for a variety of industrial purposes while it is predominantly available for purchase as a pet animal litter antibacterial at the domestic … L4873] and in other products where it may not primarily be used in the role of a non-medicinal preservative antimicrobial [L4874].
Categories: Compounds used in a research, industrial, or household settingSynonyms: 2-Bromo-2-nitropropane-1,3-diol, 2-Nitro-2-bromo-1,3-propanediolRaloxifene
go.drugbank.com/drugs/DB00481ApprovedInvestigationalHowever, it has a negligible effect on altering the development and progression of breast cancer itself. … [A4979,T28] Exhibiting tissue-specific effects distinct from [estradiol], raloxifene is the first of the benzothiophene group of antiestrogens to be labelled a SERM.
Categories: P-glycoprotein substrates, Cytochrome P-450 CYP2B6 InhibitorsSynonyms: (2-(4-Hydroxyphenyl)-6-hydroxybenzo(b)thien-3-yl)(4-(2-(1-piperidinyl)ethoxy)phenyl)methanoneBenzoin resin
go.drugbank.com/drugs/DB11222Approvedskin abrasions as tincture of benzoin, or benzoin in a solution of alcohol. … While benzoin resin is used as a common ingredient in incense-making and perfumery, it is also used clinically as a mild antiseptic agent in over-the-counter products to clean sores, cuts, wounds, and
Mixtures: Blistex Kank-A, Skin-E-dip OntProducts: Benzoinspray - Aer 25%Tauroursodeoxycholic acid
go.drugbank.com/drugs/DB08834ApprovedInvestigationalWithdrawnTauroursodeoxycholic acid, also known as ursodoxicoltaurine, is a highly hydrophilic tertiary bile acid [A249070] that is produced in humans at a low concentration. … [A249070] It is a taurine conjugate of [ursodeoxycholic acid] [A249065] with comparable therapeutic efficacy and safety,[A249070] but a much higher hydrophilicity.
Tislelizumab
go.drugbank.com/drugs/DB14922ApprovedInvestigationalTislelizumab is a humanized monoclonal IgG4 antibody against programmed death receptor-1 (PD-1). … [A262909] By blocking PD-L1/PD-L2–mediated cell signaling, tislelizumab restores T-cell function through cytokine production, resulting in immune-mediated antitumor responses.
Categories: PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitors, PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1) inhibitorsGallopamil
go.drugbank.com/drugs/DB12923InvestigationalGallopamil has been used in trials studying the treatment of Asthma.
Categories: Verapamil and analogues, P-glycoprotein inhibitorsTaurocholic acid
go.drugbank.com/drugs/DB04348ApprovedIt acts as a detergent to solubilize fats for absorption and is itself absorbed. It is used as a cholagogue and cholerectic.
Mixtures: Lax-BO TabCategories: Compounds used in a research, industrial, or household setting, P-glycoprotein inhibitorsGlecaprevir
go.drugbank.com/drugs/DB13879ApprovedInvestigationalIn clinical trials, this combination therapy achieved SVR12 rate, or undetectable Hepatitis C for twelve or more weeks after the end of treatment, of ≥93% across genotypes 1a, 2a, 3a, 4, 5 and 6 [L41080 … Glecaprevir is a direct acting antiviral agent and Hepatitis C virus (HCV) NS3/4A protease inhibitor that targets the the viral RNA replication.
Mixtures: MAVIRET® 100/40 MG TABLETAS RECUBIERTASCategories: NS3/4A Protease Inhibitors, HCV NS3/4A Protease InhibitorsLutropin alfa
go.drugbank.com/drugs/DB00044ApprovedInvestigationalLutropin alfa is a recombinant human luteinizing hormone produced in yeast with 2 subunits, alpha = 92 residues, beta = 121 residues. It is a heterodimeric glycoprotein made up of monomeric units. … Its pharmacological action mimics the biological activity of endogenous LH; an acute rise of LH, or LH surge, in females triggers ovulation and the development of the corpous luteum.
Mixtures: PERGOVERIS 150 IU/75 IU ENJEKSİYONLUK ÇÖZELTİ İÇİN TOZ VE ÇÖZÜCÜ, 1 ADET, PERGOVERIS 150 IU/75 IU ENJEKSİYONLUK ÇÖZELTİ İÇİN TOZ VE ÇÖZÜCÜ, 3 ADETSynonyms: Recombinant LHVoxilaprevir
go.drugbank.com/drugs/DB12026ApprovedInvestigationalFollowing viral replication of HCV genetic material and translation into a single polypeptide, Nonstructural Protein 3 (NS3) and its activating cofactor Nonstructural Protein 4A (NS4A) are responsible … Voxilaprevir is a Direct-Acting Antiviral (DAA) medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV)
Categories: NS3/4A Protease Inhibitors, HCV NS3/4A Protease Inhibitors