Identification
- Summary
Benzoin resin is a compound used to protect small wounds or canker sores.
- Generic Name
- Benzoin resin
- DrugBank Accession Number
- DB11222
- Background
Benzoin resin is a balsamic resin obtained from the bark of several species of trees in the genus Styrax. There are two common kinds of benzoin, benzoin Siam and benzoin Sumatra, that are obtained from different species of the Styrax tree. While benzoin resin is used as a common ingredient in incense-making and perfumery, it is also used clinically as a mild antiseptic agent in over-the-counter products to clean sores, cuts, wounds, and skin abrasions as tincture of benzoin, or benzoin in a solution of alcohol. Tincture of benzoin solution is a topical adhesive agent used to provide tackiness and enhance the adhesive property of tape.
- Type
- Biotech
- Groups
- Approved
- Synonyms
- Benzoin absolute
- Benzoin resin, unspecified
- Benzoin tincture, compound
- Gum benzoin
- Gum benzoin tincture
- Gum sumatra
- External IDs
- FEMA No. 2133
Pharmacology
- Indication
Indicated for mild antisepsis of skin, cuts, and abrasions.
Reduce drug development failure ratesBuild, train, & validate machine-learning modelswith evidence-based and structured datasets.Build, train, & validate predictive machine-learning models with structured datasets.- Contraindications & Blackbox Warnings
Prevent Adverse Drug Events TodayTap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events with our Clinical API- Pharmacodynamics
Benzoin resin exhibits antiseptic properties.
- Mechanism of action
The full mechanism of action is not yet fully established. Benzoic acid present in tincture of benzoin as well as the strong alcoholic content of the common pharmaceutical preparation are thought to play antiseptic and dehydrating effects on the oedematous tissue 1. Benzoin resin is thought to form a fine coating under the adhesive tapes and over skin, abrasions, wounds, and oral lesions when used as a topical adhesive agent. Antiseptic preparation maintains skin integrity and protects the skin from adhesive ingredients and body fluids.
- Absorption
No pharmacokinetic data available.
- Volume of distribution
No pharmacokinetic data available.
- Protein binding
No pharmacokinetic data available.
- Metabolism
No pharmacokinetic data available.
- Route of elimination
No pharmacokinetic data available.
- Half-life
No pharmacokinetic data available.
- Clearance
No pharmacokinetic data available.
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
No toxicokinetic data available.
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- No interactions found.
Products
Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.- Over the Counter Products
Name Dosage Strength Route Labeller Marketing Start Marketing End Region Image Benz Protect Liquid 100 mg/1mL Topical Geritrex Llc 2015-07-31 Not applicable US 
Benzoin Compound Tincture Liquid 1000 mg/1mL Topical Humco Holding Group, Inc. 2008-01-01 Not applicable US Benzoin Compound Tincture Liquid 100 mg/1mL Topical Geritrex Llc 2015-07-31 Not applicable US Benzoin Compound Tincture Professional Pack Liquid 1000 mg/1mL Topical Humco Holding Group, Inc. 1998-03-25 2020-09-30 US Benzoin Tincture Liquid 1000 mg/1mL Topical Humco Holding Group, Inc. 2008-01-01 Not applicable US - Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image Benzoin Benzoin resin (0.6 g/0.6mL) + Aloe vera leaf (.12 g/0.6mL) + Liquidambar styraciflua resin (.48 g/0.6mL) + Tolu balsam (.24 g/0.6mL) Swab Topical James Alexander Corporation 1976-10-25 2025-02-28 US Blistex Kank-A Benzoin resin (0.5 g/100mL) + Benzocaine (20 g/100mL) Liquid Buccal Blistex Inc. 2011-12-01 Not applicable US Chase Coldsorex Benzoin resin (12.46 %) + Camphor (3 %) + Levomenthol (0.62 %) + Myrrh (5 %) Liquid Topical Stella Pharmaceutical Canada Inc. 1997-09-04 2003-11-20 Canada 
Cold Sore Lotion Benzoin resin (94 %) + Camphor (4 %) + Levomenthol (2 %) Lotion Topical Stanley Pharmaceuticals, A Division Of Vita Health Products Inc. 1982-12-31 2002-07-31 Canada Cold Sore Lotion Benzoin resin (2.505 g / 100 mL) + Benzocaine (2 g / 100 mL) + Camphor (10 g / 100 mL) + Levomenthol (200 mg / 100 mL) + Myrrh (3.84 g / 100 mL) Lotion Topical D.C. Labs Limited 1966-12-31 2003-07-11 Canada - Unapproved/Other Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image Benzoin Benzoin resin (0.6 g/0.6mL) + Aloe vera leaf (.12 g/0.6mL) + Liquidambar styraciflua resin (.48 g/0.6mL) + Tolu balsam (.24 g/0.6mL) Swab Topical James Alexander Corporation 1976-10-25 2025-02-28 US
Categories
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- GK21SBA74R
- CAS number
- 9000-05-9
References
- General References
- PERLMAN HH: Compound benzoin tincture in treatment of vesiculobullous lesions of mucous membranes. Arch Derm Syphilol. 1950 Jan;61(1):119-21. [Article]
- External Links
- PubChem Substance
- 347911157
- 1406
- Wikipedia
- Benzoin_(resin)
- MSDS
- Download (67.2 KB)
Clinical Trials
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Liquid Topical 100 mg/1mL Swab Topical Liquid Topical 1000 mg/1mL Aerosol Topical 25 % Liquid Buccal Lotion Topical Tincture Topical 100 mg/1mL Liquid Topical 10 g/100mL Tincture Topical Tincture Topical 10 % Tincture Respiratory (inhalation); Topical Liquid Nasal; Respiratory (inhalation) Liquid Respiratory (inhalation) Liquid Topical Stick Topical Solution Ointment Topical Aerosol Topical - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Solid
- Experimental Properties
Property Value Source melting point (°C) 60 MSDS water solubility Insoluble MSDS
Drug created at December 03, 2015 16:51 / Updated at April 26, 2024 00:46