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Displaying results 3091 - 3100 of 10000 in total
  1. Drug

    Meticillin

    go.drugbank.com/drugs/DB01603
    ApprovedInvestigational

    One of the penicillins which is resistant to penicillinase but susceptible to a penicillin-binding protein. It is inactivated by gastric acid so administered by injection.

    Synonyms: (2S,5R,6R)-6-[(2,6-dimethoxybenzoyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-(2,6-Dimethoxybenzamido)penicillanic acidCategories: Heterocyclic Compounds, 2-Ring
  2. Drug

    Sulfachlorpyridazine

    go.drugbank.com/drugs/DB11461
    ExperimentalVet approved

    A sulfonamide antimicrobial used for urinary tract infections and in veterinary medicine.

    Synonyms: 4-Amino-N-(6-chloro-3-pyridazinyl)benzenesulfonamide, 4-amino-N-(6-chloropyridazin-3-yl)benzenesulfonamideMixtures: TP-KSM 125/625 mg/g Water Soluble Powder
  3. Drug

    Pucotenlimab

    go.drugbank.com/drugs/DB17552
    ApprovedInvestigational

    Pucotenlimab is a recombinant humanized anti-PD-1 monoclonal antibody. It received its first global approval in China in July 2022 for the treatment of solid tumours. … [A257296] It is being investigated in other cancers.

    Synonyms: Immunoglobulin g4 (252-theronine,306-proline,432-alanine), anti-(human programmed cell death 1) (human-mus musculus monoclonal hx008 .gamma.4-chain), disulfide with human-mus musculus monoclonal hx008, Humanized pd-1 blocking antibody hx-008
  4. Drug

    Orismilast

    go.drugbank.com/drugs/DB19042
    Investigational

    Orismilast is under investigation in clinical trial NCT05190419 (Study to Assess the Efficacy and Safety of Orismilast in Psoriasis).

    Synonyms: 2-(3,5-dichloro-1-oxido-4-pyridinyl)-1-(7-(difluoromethoxy)-2',3',5',6'-tetrahydro-1',1'-dioxidospiro(1,3-benzodioxole-2,4'-(4h)thiopyran)-4-yl)ethanone
  5. Drug

    Seletracetam

    go.drugbank.com/drugs/DB05885
    Investigational

    Seletracetam is a pyrrolidone derivative and with a structural similarity to newer generation antiepileptic drug levetiracetam. … As of 2010, its production was further halted due to the investigation of a newer antiepileptic agent, brivaracetam.

    Synonyms: (2S)-2-((4S)-4-(2,2-Difluoroethenyl)-2-oxopyrrolidin-1-yl)butanamideCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-Ring
  6. Drug

    (R)-warfarin

    go.drugbank.com/drugs/DB08496
    Experimental

    S-warfarin is 2-5 times more potent than the R-isomer in producing an anticoagulant response.[A1038] … Warfarin consists of a racemic mixture of two active enantiomers—R- and S- forms—each of which is cleared by different pathways.

    Synonyms: (R)-4-Hydroxy-3-(3-oxo-1-phenylbutyl)-2-benzopyrone, (R)-4-Hydroxy-3-(3-oxo-1-phenylbutyl)-2H-1-benzopyran-2-oneCategories: Vitamin K Antagonists, Cytochrome P-450 Substrates
  7. Drug

    Cadisegliatin

    go.drugbank.com/drugs/DB18886
    Investigational

    Cadisegliatin is under investigation in clinical trial NCT06334133 (Cadisegliatin as Adjunctive Therapy in Type 1 Diabetes).

    Synonyms: 2-((2-(3-cyclohexyl-3-((1r,4r)-4-propoxycyclohexyl)ureido)thiazol-5-yl)thio)acetic acid, [(2-{[cyclohexyl(trans-4-propoxycyclohexyl)carbamoyl]amino}-1,3-thiazol-5-yl)sulfanyl]acetic acid
  8. Drug

    Hispidulin

    go.drugbank.com/drugs/DB14008
    Experimental

    Hispidulin (4',5,7-trihydroxy-6-methoxyflavone) is a potent benzodiazepine (BZD) receptor ligand with positive allosteric properties [A32513].

    Synonyms: 4',5,7-Trihydroxy-6-methoxyflavone, Scutellarein 6-methyl etherCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  9. Drug

    MPT-0L055

    go.drugbank.com/drugs/DB17136
    Experimental

    Synonyms: 4-(((3-chloro-1,4-dihydro-1,4-dioxo-2-naphthalenyl)amino)methyl)-n-3-pyridinylbenzamide, 4-(((3-chloro-1,4-dioxo-1,4 dihydronaphthalen-2-yl)amino)methyl)-n-(pyridine-3-yl)benzamide
  10. Drug

    4-Nitrophenyl (3S)-3-({N-[(benzyloxy)carbonyl]-L-phenylalanyl}amino)-5-phenyl-1-pentanesulfonate

    go.drugbank.com/drugs/DB02051
    Experimental

    Synonyms: 3-[N-[Benzyloxycarbonyl]-phenylalaninyl-amino]-5-phenyl-pentane-1-sulfonic acid 4-nitro-phenyl ester, 4-Nitrophenyl (3S)-3-({N-[(benzyloxy)carbonyl]-L-phenylalanyl}amino)-5-phenyl-1-pentanesulfonate