Cadisegliatin

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Cadisegliatin
DrugBank Accession Number
DB18886
Background

Cadisegliatin is under investigation in clinical trial NCT06334133 (Cadisegliatin as Adjunctive Therapy in Type 1 Diabetes).

Type
Small Molecule
Groups
Investigational
Structure
Weight
Average: 455.63
Monoisotopic: 455.191248903
Chemical Formula
C21H33N3O4S2
Synonyms
  • [(2-{[cyclohexyl(trans-4-propoxycyclohexyl)carbamoyl]amino}-1,3-thiazol-5-yl)sulfanyl]acetic acid
  • 2-((2-(3-cyclohexyl-3-((1r,4r)-4-propoxycyclohexyl)ureido)thiazol-5-yl)thio)acetic acid
  • Acetic acid, 2-[[2-[[[cyclohexyl(trans-4-propoxycyclohexyl)amino]carbonyl]amino]-5-thiazolyl]thio]-
External IDs
  • NN-9108
  • NN9108
  • NNC 80-3315
  • TTP-00223399
  • TTP-399
  • TTP399

Pharmacology

Indication

Not Available

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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Categories

Drug Categories
Not Available
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
98S8SH8UNF
CAS number
859525-02-3
InChI Key
HPGJSAAUJGAMLV-QAQDUYKDSA-N
InChI
InChI=1S/C21H33N3O4S2/c1-2-12-28-17-10-8-16(9-11-17)24(15-6-4-3-5-7-15)21(27)23-20-22-13-19(30-20)29-14-18(25)26/h13,15-17H,2-12,14H2,1H3,(H,25,26)(H,22,23,27)/t16-,17-
IUPAC Name
SMILES
CCCO[C@H]1CC[C@@H](CC1)N(C1CCCCC1)C(=O)NC1=NC=C(SCC(O)=O)S1

References

General References
Not Available
ChemSpider
123963152
ChEMBL
CHEMBL5095262
ZINC
ZINC000149397570
Wikipedia
Cadisegliatin

Clinical Trials

Clinical Trials
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PhaseStatusPurposeConditionsCountStart DateWhy Stopped100+ additional columns
3Not Yet RecruitingTreatmentType 1 Diabetes Mellitus1somestatusstop reasonjust information to hide
2CompletedTreatmentType 2 Diabetes Mellitus1somestatusstop reasonjust information to hide
1, 2CompletedBasic ScienceType 2 Diabetes Mellitus1somestatusstop reasonjust information to hide
1, 2CompletedTreatmentType 1 Diabetes Mellitus1somestatusstop reasonjust information to hide

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available
Chromatographic Properties
Collision Cross Sections (CCS)
Not Available

Drug created at June 27, 2024 02:44 / Updated at June 28, 2024 04:46