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Hyaluronidase
go.drugbank.com/drugs/DB14740ApprovedInvestigationalHyaluronidase is an enzyme used to improve the absorption and dispersion of parenterally administered fluids, drugs, and contrast agents. … [A199026] Early research into hyaluronidase identified it as a "spreading factor" which allowed for increased permeability of the connective tissue.
Products: POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION PARA ADMINISTRACIÓN OFTALMICAAnifrolumab
go.drugbank.com/drugs/DB11976ApprovedInvestigational[A237054] The design of early clinical trials of anti-interferon treatments such as anifrolumab, rontalizumab, and sifalimumab have come under criticism. … Anifrolumab, or MEDI-546, is a type 1 interferon receptor (IFNAR) inhibiting IgG1κ monoclonal antibody indicated in the treatment of adults with moderate to severe systemic lupus erythematosus.
Products: Saphnelo 300 mg/2 mL İnfüzyonluk Çözelti Hazırlamak İçin Konsantre, 1 ADETCyanocobalamin Co-60
go.drugbank.com/drugs/DB09387ApprovedWithdrawnCyanocobalamin Co-60 is an analog of Vitamin B12 labeled with Co60. … Cyanocobalamin Co-60 was used for the diagnosis of pernicious anemia, but now it is withdrawn from the market in the US for unknown reasons.
Vanillyl butyl ether
go.drugbank.com/drugs/DB11299ApprovedVanillyl butyl ether is an ether of monohydroxybenzoic acid. It is added to food products as a flavoring agent. … It is also present in cosmetics and personal care products as a fragrance ingredient, oral care agent, hair conditioning agent, and warming or cooling agent.
Bitolterol
go.drugbank.com/drugs/DB00901ApprovedWithdrawnIt is a beta-2-adrenergic receptor agonist. Bitolterol was withdrawn from the market by Elan Pharmaceuticals in 2001.
Istisociclib
go.drugbank.com/drugs/DB21703InvestigationalIstisociclib is under investigation in clinical trial NCT04718675 (A Study of KB-0742 in Participants With Relapsed or Refractory Solid Tumors Including Platinum Resistant High Grade Serous Ovarian Cancer … Istisociclib has a monoisotopic molecular weight of 287.21 Da.
TGAAC09
go.drugbank.com/drugs/DB06363InvestigationaltgAAC09 is an investigational vaccine that utilizes an AAV vector to deliver genes that encode HIV proteins. … It was under investigation in clinical trials NCT00482027 and NCT00888446 for the treatment of HIV Infection.
Mefloquine
go.drugbank.com/drugs/DB00358ApprovedMalaria is a protozoan disease that places an enormous burden on human health in endemic areas around the world. … [L30623] Mefloquine, commonly known as Lariam, is an antimalarial drug used for the prevention and treatment of malaria caused by infection with Plasmodium vivax and Plasmodium falciparum.
Tolrestat
go.drugbank.com/drugs/DB02383ApprovedWithdrawnTolrestat (INN) (AY-27773) is an aldose reductase inhibitor which was approved for the control of certain diabetic complications. … It was sold under the tradename Alredase but was discontinued by Wyeth in 1997 because of the risk of severe liver toxicity and death.