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Tranylcypromine
go.drugbank.com/drugs/DB00752ApprovedInvestigationalTranylcypromine is a racemate comprising equal amounts of (1R,2S)- and (1S,2R)-2-phenylcyclopropan-1-amine with the chiral centers both located on the cylopropane ring. … It also is useful in panic and phobic disorders (From AMA Drug Evaluations Annual, 1994, p311).
Synonyms: (1R*,2S*)-2-phenylcyclopropan-1-amine, (±)-trans-2-phenylcyclopropylamineCategories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates, Cytochrome P-450 CYP1A2 InhibitorsTremelimumab
go.drugbank.com/drugs/DB11771ApprovedInvestigationalCTLA-4 is a cell surface receptor expressed on activated T cells to act as a negative regulator for T cells. … Tremelimumab, formerly known as ticilimumab, is a fully human IgG2 monoclonal antibody directed against cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4).
Categories: CTLA-4-directed Blocking AntibodyProducts: Imjudo 300 mg/15 ml İnfüzyonluk Çözelti Hazırlamak İçin Konsantre, 1 adet, Imjudo 25 mg/1.25 mL İnfüzyonluk Çözelti Hazırlamak İçin Konsantre, 1 adetHydroxyprogesterone caproate
go.drugbank.com/drugs/DB06789ApprovedIt is an ester derivative of 17α-hydroxyprogesterone formed from caproic acid (hexanoic acid). … FDA approved Makena from KV Pharmaceutical (previously named as Gestiva) on February 4, 2011 for prevention of preterm delivery in women with a history of preterm delivery, sparking a pricing controversy
Synonyms: 17alpha-Caproyloxypregn-4-ene-3,20-dione, 17 Hydroxyprogesterone CapronateMixtures: GRAVIDINONA 2 MLCertolizumab pegol
go.drugbank.com/drugs/DB08904ApprovedInvestigational[A176585] It is formed with a humanized Fab fragment of 50 kDa, from an IgG 1 isotype, fused to a 40 kDa polyethylene glycol moiety replacing the Fc antibody region. … [A176606] It was developed and manufactured by UCB Pharma, first FDA approved in 2008[L45018] and updated for a new indication on March 28, 2019.[L5819]
Products: CİMZİA 200 MG/ML S.C. ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR (2 ADET), CIMZIA 200 MGTriptorelin
go.drugbank.com/drugs/DB06825ApprovedInvestigationalVet approvedTriptorelin is a synthetic decapeptide agonist analog of luteinizing hormone releasing hormone (LHRH).
Synonyms: (6-D-Tryptophan)luteinizing hormone-releasing hormone, (D-Trp6)-GnRHProducts: GONAPEPTYL 0,1 MG/ML ENJEKSİYONLUK ÇÖZELTİ, 1 ADET, DECAPEPTYL DEPOT 3,75 MG INJEKSIYONLUK SUSPANSIYON ICIN TOZ VE COZUCU, 1 ADETInsulin detemir
go.drugbank.com/drugs/DB01307ApprovedInvestigational[A2358, A2359, A2360, A44] This insulin analogue has a 14-C fatty acid, myristic acid, bound to the lysine amino acid at position B29. … [A2358, A2359, A2360, A44] Marketed as the brand name product Levemir, insulin detemir has a duration of action of 16-24 hours allowing for once-daily dosing, typically at bedtime.
Categories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 Enzyme InducersProducts: LEVEMIR PENFİLL 100 U/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KARTUŞ, 5 ADET, 100 U/MLNirsevimab
go.drugbank.com/drugs/DB16258ApprovedInvestigational[L44146] Nirsevimab was also approved by Health Canada on April 19, 2023 and by the FDA in July 17, 2023 for the same indication.[L46392,L47461] … [L44146] It binds to the prefusion conformation of the RSV F protein, a glycoprotein involved in the membrane fusion step of the viral entry process, and neutralizes several RSV A and B strains.
Synonyms: *01 (90.1%)) (8.8.19) (1-126) -homo sapiens ighg1*03, Immunoglobulin g1-kappa, anti-(human respiratory syncytial virus fusion glycoprotein f0 (protein f))human monoclonal antibody.gamma.1 heavy chain (1-456) (human vh (homo sapiens ighv1-69*01(ighd)-ighj4Categories: Respiratory Syncytial Virus Anti-F Protein Monoclonal AntibodyIsradipine
go.drugbank.com/drugs/DB00270ApprovedIt exhibits greater selectivity towards arterial smooth muscle cells owing to alternative splicing of the alpha-1 subunit of the channel and increased prevalence of inactive channels in smooth muscle cells … It is structurally related to felodipine, nifedipine, and nimodipine and is the most potent calcium-channel blocking agent of the DHP class.
Categories: Heterocyclic Compounds, 1-Ring, P-glycoprotein inhibitorsProducts: DYNACIRC SRO 5 MG, DYNACIRC COMPRIMIDOS 2.5 MGSorafenib
go.drugbank.com/drugs/DB00398ApprovedInvestigationalSorafenib is a bi-aryl urea and an oral multikinase inhibitor. … It targets cell surface tyrosine kinase receptors and downstream intracellular kinases that are implicated in tumour cell proliferation and tumour angiogenesis.
Categories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic IndexSynonyms: N-(4-Chloro-3-(trifluoromethyl)phenyl)-N'-(4-(2-(N-methylcarbamoyl)-4-pyridyloxy)phenyl)urea, 4-(4-((((4-Chloro-3-(trifluoromethyl)phenyl)amino)carbonyl)amino)phenoxy)-N-methyl-2-pyridinecarboxamideDeferasirox
go.drugbank.com/drugs/DB01609ApprovedInvestigationalDeferasirox is an iron chelator and the first oral medication FDA approved for chronic iron overload in patients receiving long term blood transfusions.
Categories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 CYP3A InducersProducts: DEFERASIROX EG, JADENU®180 MG TABLETAS RECUBIERTAS