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Displaying results 3111 - 3120 of 10000 in total
  1. Drug

    LY-2599506

    go.drugbank.com/drugs/DB05970
    Investigational

    LY2599506 was under investigation in clinical trials NCT01024244 and NCT01029795 for the treatment of patients with type 2 diabetes.

    Synonyms: (R)-2-(4-(CYCLOPROPYLSULFONYL)PHENYL)-N-(PYRAZIN-2-YL)-3-(TETRAHYDRO-2H-PYRAN-4-YL)PROPANAMIDE, Gka (R)-1
  2. Drug

    Levacetylleucine

    go.drugbank.com/drugs/DB16956
    ApprovedInvestigational

    [A264439] Observational studies in patients with Niemann-Pick disease type C (NPC) suggested a beneficial symptomatic as well as neuroprotective disease-modifying effect of the DL-form of N-acetylleucine … Levacetylleucine (L-acetylleucine) is a modified acetylated derivative of the amino acid [leucine]. The racemic (i.e. DL-) form has been available in France since 1957 for the treatment of vertigo.

    Categories: P-glycoprotein inhibitorsSynonyms: (s)-2-acetamido-4-methylpentanoic acid, L-leucine, n-acetyl-
  3. Drug

    Edralbrutinib

    go.drugbank.com/drugs/DB18095
    Investigational

    Edralbrutinib is an orally available small molecule inhibitor of Bruton's tyrosine kinase.

    Synonyms: 4-amino-3-(4-(2,6-difluorophenoxy)phenyl)-1,6-dihydro-1-((3r)-1-(1-oxo-2-butyn-1-yl)-3-pyrrolidinyl)-7h-pyrrolo(2,3-d)pyridazin-7-one, 7h-pyrrolo(2,3-d)pyridazin-7-one, 4-amino-3-(4-(2,6-difluorophenoxy)phenyl)-1,6-dihydro-1-((3r)-1-(1-oxo-2-butyn-1-yl)-3-pyrrolidinyl)-
  4. Drug

    Soquelitinib

    go.drugbank.com/drugs/DB18749
    Investigational

    Synonyms: Cyclopropanecarboxamide, N-[5-[[5-[[(3R)-hexahydro-3-methyl-4-(1-oxo-2-propen-1-yl)-1H-1,4-diazepin-1-yl]carbonyl]-4-methoxy-2-methylphenyl]thio]-2-thiazolyl]-, N-{5-[(5-{[(3R)-4-(prop-2-enoyl)-3-methyl-1,4-diazepan-1-yl]carbonyl}-4-methoxy-2-methylphenyl)sulfanyl]-1,3-thiazol-2-yl}cyclopropanecarboxamide
  5. Drug

    Safusidenib

    go.drugbank.com/drugs/DB18745
    Investigational

    Synonyms: (2E)-3-[1-[[5-(1-Fluoro-1-methylethyl)-3-(2,4,6-trichlorophenyl)-4-isoxazolyl]carbonyl]-3-methyl-1H-indol-4-yl]-2-propenoic acid, 2-Propenoic acid, 3-[1-[[5-(1-fluoro-1-methylethyl)-3-(2,4,6-trichlorophenyl)-4-isoxazolyl]carbonyl]-3-methyl-1H-indol-4-yl]-, (2E)-
  6. Drug

    Linafexor

    go.drugbank.com/drugs/DB18031
    Investigational

    Synonyms: 1,2,4-OXADIAZOL-5(2H)-ONE, 3-(4-(3-((5-CYCLOPROPYL-3-(2,6-DICHLOROPHENYL)-4-ISOXAZOLYL)METHOXY)-8-AZABICYCLO(3.2.1)OCT-8-YL)-2-FLUOROPHENYL)-, 3-(4-((3-endo)-3-((5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4- yl)methoxy)-8-azabicyclo[3.2.1]octan-8-yl)-2-fluorophenyl)-1,2,4-oxadiazol-5(4H)-oneCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  7. Drug

    Cannabidivarin

    go.drugbank.com/drugs/DB14050
    Investigational

    CBDV has also been shown to inhibit the activity of diacylglycerol (DAG) lipase-α, the primary enzyme responsible for the synthesis of the endocannabinoid, 2-arachidonoylglycerol (2-AG) [A33296, A33347 … In October 2017 CBDV was given orphan designation by the European Medicines Agency for use in Rett Syndrome [L2952] and again in February 2018 for treatment of Fragile X Syndrome [L2951].

    Synonyms: 2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-propylbenzene-1,3-diol, CBD-V
  8. Drug

    Amiselimod

    go.drugbank.com/drugs/DB17074
    Investigational

    Synonyms: 1,3-propanediol, 2-amino-2-(2-(4-(heptyloxy)-3-(trifluoromethyl)phenyl)ethyl)-, 2-amino-2-(2-(4-heptyloxy-3-trifluoromethylphenyl)ethyl)propane-1,3-diol
  9. Drug

    SPG302

    go.drugbank.com/drugs/DB18103
    Investigational

    Synonyms: 2-(2-(2-(2-(4-benzothiazol-2-y1-phenoxy)-ethoxy)-ethoxy)-ethoxy)-ethanol, Ethanol, 2-(2-(2-(2-(4-(2-benzothiazolyl)phenoxy)ethoxy)ethoxy)ethoxy)-
  10. Drug

    QN-302

    go.drugbank.com/drugs/DB18156
    Investigational

    Synonyms: 2,7-bis(3-morpholinopropyl)-4-((2-(pyrrolidin-1-yl)ethyl)amino)-9-(4-(pyrrolidin-1-ylmethyl)phenyl)benzo[lmn][3,8]phenanthroline-1,3,6,8(2H,7H)-tetraone