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Meningococcal polysaccharide vaccine group A
go.drugbank.com/drugs/DB13889ApprovedInvestigational*N. meningitidis* is a bacteria that causes endemic and epidemic diseases including meningitis and meningococcemia. … It is subcutaneously administered as an active immunization against the invasive meningococcal disease caused by the serogroup A.
Synonyms: Neisseria meningitidis group A polysaccharide antigen, A, Meningococcal group A polysaccharideMixtures: Menomune-A/c/y/w-135, Menomune-A/c/y/w-135Ropivacaine
go.drugbank.com/drugs/DB00296ApprovedInvestigationalRopivacaine is an aminoamide local anesthetic drug marketed by AstraZeneca under the trade name Naropin. … It exists as a racemate of its S- and R-enantiomers, although the marketed form is supplied only as the purified S-enantiomer.[L42140]
Synonyms: L-N-n-propylpipecolic acid-2,6-xylidideProducts: ROVANAEST 2.0 (Ropivacaine Hydrochloride 2mg/mL Solution for Injection or Infusion USP), ROVANAEST 7.5 (Ropivacaine Hydrochloride 7.5mg/mL Solution for Injection or Infusion USP)Gabapentin enacarbil
go.drugbank.com/drugs/DB08872ApprovedIt is a prodrug of gabapentin, and indicated in adults for the treatment of Restless Legs Syndrome (RLS) and postherpetic neuralgia (PHN).
Isosorbide dinitrate
go.drugbank.com/drugs/DB00883ApprovedInvestigationalA vasodilator used in the treatment of angina pectoris. Its actions are similar to nitroglycerin but with a slower onset of action.
Categories: Vasodilators Used in Cardiac Diseases, Agents for Treatment of Hemorrhoids and Anal Fissures for Topical UseProducts: ISDN AL 20 RETARD, ISDN AL 40 RETARDZuranolone
go.drugbank.com/drugs/DB15490ApprovedInvestigational[A260791] Zuranolone was approved by the FDA on August 4th, 2023, and it is currently the only approved treatment for women with postpartum depression. … binding to a non-benzodiazepine site on the receptor.
Categories: Neuroactive Steroid Gamma-Aminobutyric Acid A Receptor Positive ModulatorDihydroergocornine
go.drugbank.com/drugs/DB11273Approved[A32965] Dihydroergocornine presents a formula of 9,10 alpha-dihydro-12'-hydroxy-2',5'alpha-bis(1-methylethyl)-ergotaman-3',6',18-trione. … [A32962] It is an artificial derivative of the crude extract of ergot and later purified, ergocornine.
Categories: Heterocyclic Compounds with 4 or More RingsCarfentanil
go.drugbank.com/drugs/DB01535IllicitInvestigationalVet approvedIt is marketed under the trade name Wildnil as a general anaesthetic agent for large animals. … Carfentanil was first synthesized in 1974 by a team of chemists at Janssen Pharmaceutica which included Paul Janssen.
DG041
go.drugbank.com/drugs/DB05027ExperimentalDG041, an anti-platelet compound, has shown to be a selective and potent antagonist of the EP3 receptor for prostaglandins E2. … DG041 is a novel, first-in-class, orally-administered small molecule developmented for the prevention of arterial thrombosis and its complications.
Tividenofusp alfa
go.drugbank.com/drugs/DB17628ApprovedInvestigationalTividenofusp alfa is a first-in-class, brain-penetrant enzyme replacement therapy (ERT) indicated for the treatment of Mucopolysaccharidosis type II (MPS II), also known as Hunter syndrome [L56097, L56099 … Hunter syndrome is a rare, X-linked lysosomal storage disorder caused by a deficiency in the enzyme iduronate-2-sulfatase (IDS), which leads to the toxic accumulation of glycosaminoglycans (GAGs) throughout
Synonyms: - L-iduronate sulfate sulfatase, EC:3.1.6.13) pro-protein (1-525), fused via the peptide linker 526 GGGGS 530 to a human immunoglobulin G1 C-terminal Fc fragment (531-757) variant (L 544>A, L 545>A, T, 676>S, L 678>A, YHexobendine
go.drugbank.com/drugs/DB13265ApprovedIt has not been approved in the United States or the United Kingdom, but has been used widely in Austria and Germany [T478]. … Hexobendine is a medication used to cause vasodilation, to treat several conditions including angina pectoris.
Categories: Vasodilators Used in Cardiac Diseases