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Displaying results 3141 - 3150 of 10000 in total
  1. Drug

    Amiloride

    go.drugbank.com/drugs/DB00594
    ApprovedInvestigational

    A pyrazine compound inhibiting sodium reabsorption through sodium channels in renal epithelial cells. … This inhibition creates a negative potential in the luminal membranes of principal cells, located in the distal convoluted tubule and collecting duct.

    Mixtures: Nu-amilzide 5/50 Mg Tab, Riva-amilzide 5/50 mgCategories: Decreased Renal K+ Excretion, Heterocyclic Compounds, 1-Ring
  2. Drug

    Dexmethylphenidate

    go.drugbank.com/drugs/DB06701
    ApprovedInvestigational

    The d-isomer is thought to have greater effect with fewer side effects than the l-isomer or the racemic mixture[A177181]. … It is a norepinephrine-dopamine reuptake inhibitor (NDRI) and thus a psychostimulant[A177193]. It is used for treatment of Attention Deficit Hyperactivity Disorder (ADHD)[Label,A177181].

    Synonyms: D-TMP, methyl (R)-phenyl[(R)-piperidin-2-yl]acetateCategories: Heterocyclic Compounds, 1-Ring
  3. Drug

    (1-Hydroxy-2-oxopiperidin-3-yl)phosphonic acid

    go.drugbank.com/drugs/DB17108
    Experimental

    Synonyms: (1-Hydroxy-2-oxopiperidin-3-yl)phosphonic acid, Phosphonic acid, p-(1-hydroxy-2-oxo-3-piperidinyl)-
  4. Drug

    LCL-161

    go.drugbank.com/drugs/DB12085
    Investigational

    LCL161 has been used in trials studying the treatment of Leukemia, Neoplasms, Solid Tumors, Breast Cancer, and Ovarian Cancer, among others.

    Synonyms: (2S)-N-[(1S)-1-cyclohexyl-2-[(2S)-2-[4-(4-fluorobenzoyl)-1,3-thiazol-2-yl]pyrrolidin-1-yl]-2-oxoethyl]-2-(methylamino)propanamideCategories: Proto-Oncogene Proteins c-bcl-2, antagonists & inhibitors, Heterocyclic Compounds, 1-Ring
  5. Drug

    2-(4-hydroxyphenyl)benzo[b]thiophen-6-ol

    go.drugbank.com/drugs/DB08773
    Experimental

    Synonyms: 2-(4-hydroxyphenyl)benzo(b)thiophene-6-ol, 2-(4-hydroxyphenyl)benzo[b]thiophen-6-ol
  6. Drug

    1-[4-(Octahydro-Pyrido[1,2-a]Pyrazin-2-Yl)-Phenyl]-2-Phenyl-1,2,3,4-Tetrahydro-Isoquinolin-6-Ol

    go.drugbank.com/drugs/DB03802
    Experimental

    Synonyms: 1-[4-(Octahydro-Pyrido[1,2-a]Pyrazin-2-Yl)-Phenyl]-2-Phenyl-1,2,3,4-Tetrahydro-Isoquinolin-6-Ol
  7. Drug

    (6R)-2-amino-6-[2-(3'-methoxybiphenyl-3-yl)ethyl]-3,6-dimethyl-5,6-dihydropyrimidin-4(3H)-one

    go.drugbank.com/drugs/DB07519
    Experimental

    Synonyms: (6R)-2-amino-6-[2-(3'-methoxybiphenyl-3-yl)ethyl]-3,6-dimethyl-5,6-dihydropyrimidin-4(3H)-one
  8. Drug

    2-{4-[(4-imidazo[1,2-a]pyridin-3-ylpyrimidin-2-yl)amino]piperidin-1-yl}-N-methylacetamide

    go.drugbank.com/drugs/DB08026
    Experimental

    Synonyms: 2-{4-[(4-imidazo[1,2-a]pyridin-3-ylpyrimidin-2-yl)amino]piperidin-1-yl}-N-methylacetamide
  9. Drug

    4-{[(2-Oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]amino}-N-(1,3-thiazol-2-yl)benzenesulfonamide

    go.drugbank.com/drugs/DB08125
    Experimental

    Synonyms: 4-{[(2-Oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]amino}-N-(1,3-thiazol-2-yl)benzenesulfonamide
  10. Drug

    S-(2-{[N-(2-HYDROXY-4-{[HYDROXY(OXIDO)PHOSPHINO]OXY}-3,3-DIMETHYLBUTANOYL)-BETA-ALANYL]AMINO}ETHYL) HEPTANETHIOATE

    go.drugbank.com/drugs/DB08405
    Experimental

    Synonyms: S-(2-{[N-(2-HYDROXY-4-{[HYDROXY(OXIDO)PHOSPHINO]OXY}-3,3-DIMETHYLBUTANOYL)-BETA-ALANYL]AMINO}ETHYL) HEPTANETHIOATE